5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine

Product Name: 5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine
CAS No.: 1363380-51-1
Chemical Name: 5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine
Synonyms: arotrectinib CNPP Impurity;Larotrectinib CNPP Impurity;5-Chloro-3-nitropyrazolo[...;Chloro-3-nitropyrazolo[1,5-a]pyrimidine;5-Chloro-3-nitropyrazolo[1,5-a]pyriMidin;5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine;5-chloro-3-nitropyrazole [1,5-a] pyrimidine;Pyrazolo[1,5-a]pyrimidine, 5-chloro-3-nitro-;5-chloro-3-nitropyrazolo[1,5-a]pyrimidine (Nitro );Larotrectinib Impurity 1（Larotrectinib CNPP Impurity）
CBNumber: CB22582618
Molecular Formula: C6H3ClN4O2
Formula Weight: 198.57
MOL File: 1363380-51-1.mol

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5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine Property

Melting point:: 163 - 165°C
Density: 1.85±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: Chloroform (Slightly, Heated), DMSO (Slightly)
form: Solid
pka: -3.59±0.40(Predicted)
color: Purple

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: C371555
Product name: 5-Chloro-3-nitro-pyrazolo[1,5-a]pyrimidine
Packaging: 250mg
Price: $130
Updated: 2021/12/16

ChemScene

Product number: CS-M3730
Product name: Pyrazolo[1,5-a]pyrimidine,5-chloro-3-nitro-
Purity: 97.75%
Packaging: 5g
Price: $141
Updated: 2021/12/16

ChemScene

Product number: CS-M3730
Product name: Pyrazolo[1,5-a]pyrimidine,5-chloro-3-nitro-
Purity: 97.75%
Packaging: 1g
Price: $33
Updated: 2021/12/16

Apolloscientific

Product number: OR52568
Product name: 5-Chloro-3-nitropyrazolo[1,5-a]pyrimidine
Purity: 97%
Packaging: 5g
Price: $219
Updated: 2021/12/16

AK Scientific

Product number: 0771DW
Product name: 5-Chloro-3-nitropyrazolo[1,5-A]pyrimidine
Packaging: 5g
Price: $228
Updated: 2021/12/16

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5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine Chemical Properties,Usage,Production

Uses

5-Chloro-3-nitro-pyrazolo[1,5-a]pyrimidine is used in the preparation of (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide, a tyrosine kinase (TRK) inhibitor for treating cancer.

5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine Suppliers

China 145 India 7 United Kingdom 1 United States 8 Global 161

Shandong Zhonghan Pharmaceutical Co.,Ltd.

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ProdList: 205
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Shanghai Boyle Chemical Co., Ltd.

Tel
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Energy Chemical

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Wuhan Sunrise Technology Development Co., Ltd.

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Shanghai Hope Chem Co., Ltd.，

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Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
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View Lastest Price from 5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: 5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine 1363380-51-1
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 ton
Release date: 2024-12-16

Nanjing Fred Technology Co., Ltd

Product: 5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine 1363380-51-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1 ton
Release date: 2023-12-26

Hebei Yanxi Chemical Co., Ltd.

Product: 5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine 1363380-51-1
Price: US $40.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 10 tons
Release date: 2023-09-07

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1363380-51-1