ChemicalBook > CAS DataBase List > L-4,5,6,7-TETRAHYDRO-1H-IMIDAZO[4,5-C]PYRIDINE-6-CARBOXYLIC ACID

L-4,5,6,7-TETRAHYDRO-1H-IMIDAZO[4,5-C]PYRIDINE-6-CARBOXYLIC ACID

Product Name
L-4,5,6,7-TETRAHYDRO-1H-IMIDAZO[4,5-C]PYRIDINE-6-CARBOXYLIC ACID
CAS No.
59981-63-4
Chemical Name
L-4,5,6,7-TETRAHYDRO-1H-IMIDAZO[4,5-C]PYRIDINE-6-CARBOXYLIC ACID
Synonyms
SPINACINE;(6S)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-6-carbox;4,5,6,7-Tetrahydro-3H-imidazo[4,5-c]pyridine-6α-carboxylic acid;4,5,6,7-TETRAHYDRO-1H-IMIDAZOL[4,5-C]PYRIDINE-6-CARBOXYLIC ACID;Inhibitor,(S)-Spinacine,Spinacine,inhibit,Endogenous Metabolite;L-4,5,6,7-TETRAHYDRO-1H-IMIDAZO[4,5-C]PYRIDINE-6-CARBOXYLIC ACID;L-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-6-carboxylic acid;(S)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-6-carboxylic acid;(S)-4,5,6,7-Tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid;(6S)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-6-carboxylic acid
CBNumber
CB2258821
Molecular Formula
C7H9N3O2
Formula Weight
167.17
MOL File
59981-63-4.mol
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L-4,5,6,7-TETRAHYDRO-1H-IMIDAZO[4,5-C]PYRIDINE-6-CARBOXYLIC ACID Property

storage temp. 
2-8°C
solubility 
Soluble in DMSO
pka
pK1:1.649(+2);pK2:4.936(+1);pK3:8.663(0) (25°C)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
T204600
Product name
4,5,6,7-Tetrahydro-1H-imidazol[4,5-c]pyridine-6-carboxylicAcid
Packaging
100mg
Price
$45
Updated
2021/12/16
TRC
Product number
T204600
Product name
4,5,6,7-Tetrahydro-1H-imidazol[4,5-c]pyridine-6-carboxylicAcid
Packaging
500mg
Price
$130
Updated
2021/12/16
TRC
Product number
T204600
Product name
4,5,6,7-Tetrahydro-1H-imidazol[4,5-c]pyridine-6-carboxylicAcid
Packaging
1g
Price
$200
Updated
2021/12/16
ChemScene
Product number
CS-0063803
Product name
Spinacine
Purity
≥97.0%
Packaging
250mg
Price
$65
Updated
2021/12/16
AK Scientific
Product number
7292AH
Product name
L-4,5,6,7-Tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylicacid
Packaging
250mg
Price
$104
Updated
2021/12/16
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L-4,5,6,7-TETRAHYDRO-1H-IMIDAZO[4,5-C]PYRIDINE-6-CARBOXYLIC ACID Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder

Uses

Spinacine is an alkaloid inhibitor of GABA (γ-aminobutyric acid) absorption that can be isolated from spinach leaf extract[1][2].

Definition

ChEBI: Spinacine is an alpha-amino acid.

Synthesis Reference(s)

Journal of Medicinal Chemistry, 27, p. 564, 1984 DOI: 10.1021/jm00371a002

IC 50

Human Endogenous Metabolite

References

[1] Boreisha, et al. Spinacine—an inhibitor of γ-aminobutyric acid uptake. Pharmaceutical Chemistry Journal 22.1 (1988): 15-17.
[2] Dymińska, et al. "Spectroscopic properties of spinacine–an active component of ginseng (Panax ginseng) and spinach (Spinacia oleracea)." Spectroscopy Letters 49.10 (2016): 635-646.

L-4,5,6,7-TETRAHYDRO-1H-IMIDAZO[4,5-C]PYRIDINE-6-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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L-4,5,6,7-TETRAHYDRO-1H-IMIDAZO[4,5-C]PYRIDINE-6-CARBOXYLIC ACID Suppliers

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59981-63-4, L-4,5,6,7-TETRAHYDRO-1H-IMIDAZO[4,5-C]PYRIDINE-6-CARBOXYLIC ACIDRelated Search:

(S)-4,5,6,7-Tetrahydro-3-phenylmethyl-3H-imidazo[4,5-c]pyridine-6-carboxylic acid (S)-4,5,6,7-Tetrahydro-3-phenylmethyl-3H-imidazo[4,5-c]pyridine-6-carboxylic acid dihydrochloride 4,5,6,7-TETRAHYDRO-1H-IMIDAZO[4,5-C]PYRIDINE 4,5,6,7-TETRAHYDRO-1H-IMIDAZO[4,5-C]PYRIDINE-6-CARBOXYLIC ACID L-4,5,6,7-TETRAHYDRO-1H-IMIDAZO[4,5-C]PYRIDINE-6-CARBOXYLIC ACID PD 123319 ditrifluoroacetate 4-PHENYL-4,5,6,7-TETRAHYDRO-1H-IMIDAZO [4,5-C]PYRIDINE-6-CARBOXYLIC ACID 5-(ANILINOCARBONOTHIOYL)-4,5,6,7-TETRAHYDRO-3H-IMIDAZO[4,5-C]PYRIDINE-6-CARBOXYLIC ACID HYDROCHLORIDE 4-(2-HYDROXY-PHENYL)-4,5,6,7-TETRAHYDRO-1H-IMIDAZO[4,5-C]PYRIDINE-6-CARBOXYLIC ACID 5-BOC -4,5,6,7-TETRAHYDRO-3H-IMIDAZO[4,5-C]PYRIDINE-6-CARBOXYLIC ACID 4-(4-FLUORO-PHENYL)-4,5,6,7-TETRAHYDRO-3H-IMIDAZO[4,5-C]PYRIDINE-6-CARBOXYLIC ACID 4,5,6,7-TETRAHYDRO-3H-IMIDAZO[4,5-C]PYRIDINE-6-CARBOXYLIC ACID HYDROCHLORIDE 4-(4-CHLORO-PHENYL)-4,5,6,7-TETRAHYDRO-3H-IMIDAZO[4,5-C]PYRIDINE-6-CARBOXYLIC ACID 4-(2-TRIFLUOROMETHYL-PHENYL)-4,5,6,7-TETRAHYDRO-3H-IMIDAZO[4,5-C]PYRIDINE-6-CARBOXYLIC ACID 4-PYRIDIN-4-YL-4,5,6,7-TETRAHYDRO-3H-IMIDAZO[4,5-C]PYRIDINE-6-CARBOXYLIC ACID 4-(5-METHYL-FURAN-2-YL)-4,5,6,7-TETRAHYDRO-3H-IMIDAZO[4,5-C]PYRIDINE-6-CARBOXYLIC ACID 4-(4-TERT-BUTYL-PHENYL)-4,5,6,7-TETRAHYDRO-3H-IMIDAZO[4,5-C]PYRIDINE-6-CARBOXYLIC ACID 4-(3-FLUORO-PHENYL)-4,5,6,7-TETRAHYDRO-3H-IMIDAZO[4,5-C]PYRIDINE-6-CARBOXYLIC ACID

  • L-4,5,6,7-TETRAHYDRO-1H-IMIDAZO[4,5-C]PYRIDINE-6-CARBOXYLIC ACID
  • (S)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-6-carboxylic acid
  • L-4,5,6,7-Tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid≥ 99% (Assay by titration)
  • 4,5,6,7-TETRAHYDRO-1H-IMIDAZOL[4,5-C]PYRIDINE-6-CARBOXYLIC ACID
  • SPINACINE
  • (S)-4,5,6,7-Tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid
  • 4,5,6,7-Tetrahydro-3H-imidazo[4,5-c]pyridine-6α-carboxylic acid
  • 3H-Imidazo[4,5-c]pyridine-6-carboxylic acid, 4,5,6,7-tetrahydro-, (6S)-
  • (6S)-4,5,6,7-Tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid
  • (6S)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-6-carboxylic acid
  • (6S)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-6-carboxylic acid dihydrate
  • (6S)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-6-carbox
  • Inhibitor,(S)-Spinacine,Spinacine,inhibit,Endogenous Metabolite
  • L-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-6-carboxylic acid
  • 59981-63-4
  • Miscellaneous Natural Products
  • 1