PD 123319 ditrifluoroacetate

Product Name: PD 123319 ditrifluoroacetate
CAS No.: 130663-39-7
Chemical Name: PD 123319 ditrifluoroacetate
Synonyms: CS-953;PD 123,319;PD123319 TFA;PD123319, >=98%;(S)-(+)-PD 123319;ditrifluoroacetate;PD-123319 TFA salt;PD-123319 free base;PD 123319 ditrifluor;(S)-(+)-PD 123319|||PD123319
CBNumber: CB3669147
Molecular Formula: C31H32N4O3
Formula Weight: 508.61
MOL File: 130663-39-7.mol

More

Less

PD 123319 ditrifluoroacetate Property

Boiling point:: 775.8±60.0 °C(Predicted)
Density: 1.22±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: H₂O: 12 mg/mL
form: powder
pka: 2.80±0.20(Predicted)
Water Solubility: Soluble to 100 mM in water

More

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26
WGK Germany: 3

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Tocris

Product number: 1361
Product name: PD123319ditrifluoroacetate
Purity: ≥99%(HPLC)
Packaging: 10
Price: $231
Updated: 2021/12/16

Tocris

Product number: 1361
Product name: PD123319ditrifluoroacetate
Purity: ≥99%(HPLC)
Packaging: 50
Price: $903
Updated: 2021/12/16

Usbiological

Product number: 462090
Product name: PD 123319
Packaging: 10mg
Price: $439
Updated: 2021/12/16

Usbiological

Product number: 256179
Product name: PD 123319 ditrifluoroacetate
Packaging: 10mg
Price: $480
Updated: 2021/12/16

TRC

Product number: P217705
Product name: PD123319
Packaging: 10mg
Price: $140
Updated: 2021/12/16

More

Less

PD 123319 ditrifluoroacetate Chemical Properties,Usage,Production

Uses

PD 123319 is a selective non-peptide angiotensin AT2 receptor antagonist.

Definition

ChEBI: An imidazopyridine consisting of 4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine having 4-(dimethylamino)-3-methylbenzyl, diphenylacetyl and carboxy and groups at positions 1, 5 and 6 respectively

Biological Activity

Potent, selective, non-peptide angiotensin AT 2 receptor antagonist. IC 50 values are 34 and 210 nM in rat adrenal tissue and brain respectively.

References

[1] blankley c j, hodges j c, klutchko s r, et al. synthesis and structure-activity relationships of a novel series of non-peptide angiotensin ii receptor binding inhibitors specific for the at2 subtype. journal of medicinal chemistry, 1991, 34(11): 3248-3260.
[2] boulay g, servant g, luong t t, et al. modulation of angiotensin ii binding affinity by allosteric interaction of polyvinyl sulfate with an intracellular domain of the dup-753-sensitive angiotensin ii receptor of bovine adrenal glomerulosa. molecular pharmacology, 1992, 41(4): 809-815.
[3] siragy h. angiotensin ii receptor blockers: review of the binding characteristics. the american journal of cardiology, 1999, 84(10): 3-8.

PD 123319 ditrifluoroacetate Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

PD 123319 ditrifluoroacetate Suppliers

China 84 Europe 1 Germany 3 Switzerland 2 The Netherlands 1 United Kingdom 3 United States 16 Global 110

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: meilunui@163.com
Country: China
ProdList: 4727
Advantage: 58

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-400-6206333 18521732826
Fax: 021-50323701
Email: market@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

Shanghai Witofly Chemical Co.,Ltd

Tel
Email: sales@witofly.com
Country: China
ProdList: 2864
Advantage: 52

CEG Chemical Science&Technology Co., Ltd.

Tel: Mobile:13665161512
Fax: +86-510-68873513
Country: China
ProdList: 1785
Advantage: 58

Shanghai JONLN Reagent Co., Ltd.

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: 422131432@qq.com
Country: China
ProdList: 9978
Advantage: 55

Shanghai HuanChuan Industry Co.,Ltd.

Tel: 021-61478794
Fax: 021-61478794
Email: sales@hcshhai.com
Country: China
ProdList: 9793
Advantage: 50

AdooQ Bioscience CHINA

Tel: 025-58849295 18951903616;
Fax: 025-68650336
Email: info@adooq.cn
Country: China
ProdList: 2990
Advantage: 60

LETOPHARM LIMITED

Tel: +86-21-5821 5861
Fax: +86-21-5106 2861
Email: sales@letopharm.com
Country: China
ProdList: 2384
Advantage: 58

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

More

Less

View Lastest Price from PD 123319 ditrifluoroacetate manufacturers

Career Henan Chemical Co

Product: PD 123,319 DITRIFLUOROACETATE 130663-39-7
Price: US $2.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2018-12-23

130663-39-7, PD 123319 ditrifluoroacetateRelated Search:

PD 173074 PD 166285 PD 166866 PD 0325901 xav-939 Cabozantinib 2-METHOXYESTRADIOL Vismodegib (GDC-0449) S3I-201 Rapamycin L-4,5,6,7-TETRAHYDRO-1H-IMIDAZO[4,5-C]PYRIDINE-6-CARBOXYLIC ACID 4,5,6,7-TETRAHYDRO-1H-IMIDAZO[4,5-C]PYRIDINE-6-CARBOXYLIC ACID PD 123319 ditrifluoroacetate

1-[[4-(DIMETHYLAMINO)-3-METHYLPHENYL]METHYL]-5-(DIPHENYLACETYL)-4,5,6,7-TETRAHYDRO-1H-IMIDAZO[4,5-C]PYRIDINE-6-CARBOXYLIC ACID DITRIFLUOROACETATE

(3S)-9-[(4-DIMETHYLAMINO-3-METHYL-PHENYL)METHYL]-4-(2,2-DIPHENYLACETYL)-4,7,9-TRIAZABICYCLO[4.3.0]NONA-7,10-DIENE-3-CARBOXYLIC ACID

PD 123,319

PD 123,319 DITRIFLUOROACETATE

S(+)-1-[[4-(DIMETHYLAMINO)-3-METHYLPHENYL]METHYL]-5-(DIPHENYLACETYL)-4,5,6,7-TETRAHYDRO-1H-IMIDAZOL[4,5-C]PYRIDINE-6-CARBOXYLIC ACID DITRIFLUOROACETATE

PD 123,319 DITRIFLUOROACETATE POTENT AND SELECTIVE

1-((4-(Dimethylamino)-3-methylphenyl)methyl)-5-(diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4.5-c]pyridine-6-carboxyli

CS-953

pd 123,319 di(trifluoroacetate) salt

s-(+)-1-[(4-(dimethylamino)-3-methylphenyl)methyl]-5-(diphenylacetyl)-4,5,6,7-tetrahydro-1h-imidazo[4,5-c]pyridine-6-carboxylic acid ditrifluoroacetate

(6S)-1-[[4-(Dimethylamino)-3-methylphenyl]methyl]-5-(diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6α-carboxylic acid

(6S)-1-[4-(Dimethylamino)-3-methylbenzyl]-5-(diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid

(6S)-1-[4-Dimethylamino-3-methylbenzyl]-5-diphenylacetyl-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6α-carboxylic acid

1H-Imidazo(4,5-C)pyridine-6-carboxylic acid, 1-((4-(dimethylamino)-3-methylphenyl)methyl)-5-(diphenylacetyl)-4,5,6,7-tetrahydro-, (S)-

1H-IMidazo[4,5-c]pyridine-6-carboxylic acid, 1-[[4-(diMethylaMino)-3-Methylphenyl]Methyl]-5-(2,2-diphenylacetyl)-4,5,6,7-tetrahydro-, (6S)-

ditrifluoroacetate

(S)-(+)-PD 123319

(6S)-1-[[4-(Dimethylamino)-3-methylphenyl]methyl]-5-(2,2-diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid

PD123319 TFA

1-[[4-(dimethylamino)-3-methylphenyl]methyl]-5-(2,2-diphenylacetyl)-6,7-dihydro-4H-imidazo[4,5-c]pyridine-6-carboxylic acid

PD123319, >=98%

PD-123319 TFA salt

PD 123319 ditrifluoroacetate USP/EP/BP

PD 123319 ditrifluor

PD-123319 free base

(S)-(+)-PD 123319|||PD123319

130663-39-7

C31H32N4O32CF3CO2H

Inhibitors

Angiotensin