ChemicalBook > CAS DataBase List > N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea

N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea

Product Name
N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea
CAS No.
1207360-89-1
Chemical Name
N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea
Synonyms
CS-695;RG-7603;GDC-0349;GDC-0349, RG7603;GDC-0349;GDC0349;GDC0349;GDC 0349;GDC 0349;GDC-0349 RG7603 GDC0349 RG-7603;(S)-1-Ethyl-3-(4-(4-(3-methylmorpholino)-7-(oxetan-3-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimi;(S)-1-ethyl-3-(4-(4-(3-methylmorpholino)-7-(oxetan-3-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)phenyl)urea;N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea
CBNumber
CB22604233
Molecular Formula
C24H32N6O3
Formula Weight
452.55
MOL File
1207360-89-1.mol
More
Less

N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea Property

Boiling point:
571.3±50.0 °C(Predicted)
Density 
1.269
storage temp. 
Store at -20°C
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:9): 0.1 mg/ml; Ethanol: 10 mg/ml
form 
Powder
pka
13.87±0.46(Predicted)
color 
Light yellow to yellow
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
24058
Product name
GDC-0349
Purity
≥98%
Packaging
500μg
Price
$33
Updated
2024/03/01
Cayman Chemical
Product number
24058
Product name
GDC-0349
Purity
≥98%
Packaging
1mg
Price
$62
Updated
2024/03/01
Cayman Chemical
Product number
24058
Product name
GDC-0349
Purity
≥98%
Packaging
5mg
Price
$238
Updated
2024/03/01
Cayman Chemical
Product number
24058
Product name
GDC-0349
Purity
≥98%
Packaging
10mg
Price
$443
Updated
2024/03/01
ApexBio Technology
Product number
A1642
Product name
1-ethyl-3-[4-[4-[(3S)-3-methylmorpholin-4-yl]-7-(oxetan-3-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea
Packaging
5mg
Price
$120
Updated
2021/12/16
More
Less

N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea Chemical Properties,Usage,Production

Uses

N-Ethyl-N''-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea is a potent and selective mTOR inhibitor with dose-dependent efficacy in mouse xenograft cancer models.

Uses

N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea is a potent and selective mTOR inhibitor with dose-dependent efficacy in mouse x enograft cancer models.

target

mTOR

N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea Suppliers

Canada 1 China 68 India 1 United States 15 Global 85
More
Less

View Lastest Price from N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea manufacturers

Career Henan Chemical Co
Product
N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea 1207360-89-1
Price
US $1.00/KG
Min. Order
1KG
Purity
95-99%
Supply Ability
1ton
Release date
2019-12-31

1207360-89-1, N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]ureaRelated Search:

N,N'-Ethylenebis(stearamide) Deionized water 2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride GDC-0084 INK 128 (MLN0128) BX-912 Selumetinib Torin 2 Trametinib AZD2014

  • GDC-0349
  • N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea
  • RG-7603
  • Urea, N-ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]-
  • GDC-0349 N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea
  • (S)-1-ethyl-3-(4-(4-(3-methylmorpholino)-7-(oxetan-3-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)phenyl)urea
  • (S)-1-Ethyl-3-(4-(4-(3-methylmorpholino)-7-(oxetan-3-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimi
  • CS-695
  • GDC-0349, RG7603
  • GDC0349;GDC 0349;GDC 0349
  • GDC-0349;GDC0349
  • N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea USP/EP/BP
  • GDC-0349 RG7603 GDC0349 RG-7603
  • 1207360-89-1
  • Inhibitors
  • PI3K/Akt/mTOR
  • Akt
  • mTOR
  • PI3K