ChemicalBook > CAS DataBase List > N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester

N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester

Product Name
N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester
CAS No.
1256490-31-9
Chemical Name
N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester
Synonyms
EOS-61207;Redesivir Impurity 26;2. N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine;isopropyl((S)-(4-nitrophenoxy)(phenoxy)phosphoryl)-L-alaninate;N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-methyl...;N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-methylethyl este;N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester;(S)-Isopropyl 2-(((S)-(4-nitrophenoxy)(phenoxy)phosphoryl)amino)propanoate;L-Alanine, N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-, 1-Methylethyl ester
CBNumber
CB22604354
Molecular Formula
C18H21N2O7P
Formula Weight
408.34
MOL File
1256490-31-9.mol
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N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester Property

Melting point:
62-66℃
Boiling point:
514.3±60.0 °C(Predicted)
Density 
1.302
storage temp. 
2-8°C
solubility 
Dichloromethane, Ethyl Acetate, Methanol
pka
-5.78±0.70(Predicted)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
N497030
Product name
N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine1-MethylethylEster
Packaging
5mg
Price
$220
Updated
2021/12/16
TRC
Product number
N497030
Product name
N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine1-MethylethylEster
Packaging
10mg
Price
$385
Updated
2021/12/16
TRC
Product number
N497030
Product name
N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine1-MethylethylEster
Packaging
25mg
Price
$870
Updated
2021/12/16
ChemScene
Product number
CS-0011516
Product name
L-Alanine,N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-,1-methylethylester
Packaging
25mg
Price
$750
Updated
2021/12/16
ChemScene
Product number
CS-0011516
Product name
L-Alanine,N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-,1-methylethylester
Packaging
100mg
Price
$2250
Updated
2021/12/16
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N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester Chemical Properties,Usage,Production

Uses

N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl Ester is an intermediate in the synthesis of Sofosbuvir (R)-Phosphate (S675615), which is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester manufacturers

Career Henan Chemical Co
Product
N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester 1256490-31-9
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
150KG
Release date
2019-07-09

1256490-31-9, N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl esterRelated Search:

(2S,3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-ol Remdesivir impurity-1 2-ethylbutyl ((R)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate Remdesivir R-18 Remdesivir Impurity 44 R-20 impurity 5 (2R,3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-ol R-19-impurity 4 Remdesivir impurity Remdesivir Impurity 39 (2S)-2-ethylbutyl 2-(((((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate

  • N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester
  • L-Alanine, N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-, 1-Methylethyl ester
  • 2. N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine
  • N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-methylethyl este
  • isopropyl((S)-(4-nitrophenoxy)(phenoxy)phosphoryl)-L-alaninate
  • (S)-Isopropyl 2-(((S)-(4-nitrophenoxy)(phenoxy)phosphoryl)amino)propanoate
  • EOS-61207
  • N-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 1-methyl...
  • Redesivir Impurity 26
  • 1256490-31-9
  • C18H21N2O7P