ChemicalBook > CAS DataBase List > BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl-

BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl-

Product Name
BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl-
CAS No.
300586-90-7
Chemical Name
BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl-
Synonyms
OAC1;CS-2147;OAC1, >98%;OAC1;OAC-1;BAS 00287861;OAC1;OAC-1;OAC 1;OAC1 (BAS 00287861);OAC1;OAC-1;OAC 1;BAS 00287861;iPSC Induction Enhancer II, OAC1;N-1H-Pyrrolo[2,3-c]pyridin-5-ylbenzamide
CBNumber
CB22608044
Molecular Formula
C14H11N3O
Formula Weight
237.26
MOL File
300586-90-7.mol
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BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl- Property

Boiling point:
386.6±22.0 °C(Predicted)
Density 
1.363±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: soluble20mg/mL, clear
pka
11.76±0.43(Predicted)
form 
powder
color 
white to beige
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Safety

WGK Germany 
3
HS Code 
2933.99.8290
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0651
Product name
OAC1
Purity
≥98% (HPLC)
Packaging
5mg
Price
$98.4
Updated
2024/03/01
Sigma-Aldrich
Product number
5.00501
Product name
iPSC Induction Enhancer II, OAC1 - CAS 300586-90-7 - Calbiochem
Packaging
25MG
Price
$246
Updated
2023/01/07
Sigma-Aldrich
Product number
SML0651
Product name
OAC1
Purity
≥98% (HPLC)
Packaging
25mg
Price
$428
Updated
2022/05/15
TCI Chemical
Product number
O0490
Product name
OAC1
Purity
>98.0%(GC)
Packaging
10mg
Price
$149
Updated
2024/03/01
TCI Chemical
Product number
O0490
Product name
OAC1
Purity
>98.0%(GC)
Packaging
50mg
Price
$447
Updated
2024/03/01
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BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl- Chemical Properties,Usage,Production

Uses

OAC1 enhances iPSC reprogramming efficiency.

General Description

A cell-permeable pyrrolopyridinyl-benzamide compound that is reported to enhance the efficiency of 4F/4TF-induced iPSC generation from MEFs cultured in either feeder cell-containing ESC media or in feeder-/serum-free iSF1 media (1 μM OAC1 treatment starts 48 h after viral transduction). OCA1 is shown to increase cellular Oct4, Nanog, Sox2, and Tet1 mRNA levels via a yet unidentified mechanism, although OAC1 is reported not affect Oct4 promoter methylation, cellular Wnt signaling, or p53 and p21 mRNA levels. Six other iPSC reprogramming improving reagents, AM580, AzaC, BIX-01294 (Cat. No. 382190), Tranylcypromine (Cat. No. 616431), VPA (Cat. No. 676380), and Vitamin C (Cat. No. 1813), in comparison, do not exhibit Oct4 and Nanog promoters enhancing activity, while BIO (Cat. No. 361550) is demonstrated to be 3.8- and 6-fold less potent than OAC1, respectively, in inducing Oct4 and Nanog transcription.

Please note that the molecular weight for this compound is batch-specific due to variable water content. Please refer to the vial label or the certificate of analysis for the batch-specific molecular weight. The molecular weight provided represents the baseline molecular weight without water.

Biochem/physiol Actions

Cell permeable: yes

storage

+4°C

BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl- Preparation Products And Raw materials

Raw materials

Preparation Products

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BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl- Suppliers

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View Lastest Price from BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl- manufacturers

Career Henan Chemical Co
Product
BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl- 300586-90-7
Price
US $1.00/KG
Min. Order
1KG
Purity
95%~99%
Supply Ability
per week 100kg
Release date
2019-09-05

300586-90-7, BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl-Related Search:

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  • BAS 00287861
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  • iPSC Induction Enhancer II, OAC1 - CAS 300586-90-7 - Calbiochem
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  • 300586-90-7
  • Inhibitors