ChemicalBook > CAS DataBase List > (alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride

(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride

Product Name
(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride
CAS No.
521284-22-0
Chemical Name
(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride
Synonyms
Mirabegron INT 3;Mirabegron Impurity M;Mirabegron Impurity 3 HCl;DarunavirDiamino(2S,3S)Isomer;Mirabegron Impurity 20 Hydrochloride;(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]m;(R)-alpha-[[[2-(4-AMinophenyl)ethyl]aMino]Methyl];(R)-2-(4-aminophenethylamino)-1- Phenylethanol HCL;(R)-2-[2-(4-Amino-phenyl)-ethylamino]-1-phenyl-ethanol HCl;(R)--[[[2-(4-aminophenyl)ethyl]amino]methyl]-Benzenemethanol
CBNumber
CB22614397
Molecular Formula
C16H21ClN2O
Formula Weight
292.81
MOL File
521284-22-0.mol
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(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride Property

Density 
1145 at 20℃
vapor pressure 
0.015Pa at 25℃
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Powder
Stability:
Hygroscopic
LogP
-1.35 at 20℃ and pH5.79
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
A622675
Product name
(R)-2-((4-Aminophenethyl)amino)-1-phenylethanolHydrochloride
Packaging
50g
Price
$730
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA156821
Product name
(R)-2-((4-Aminophenethyl)amino)-1-phenylethanol hydrochloride
Packaging
10g
Price
$130
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA156821
Product name
(R)-2-((4-Aminophenethyl)amino)-1-phenylethanol hydrochloride
Packaging
5G
Price
$80
Updated
2021/12/16
AK Scientific
Product number
0031AP
Product name
(1R)-2-{[2-(4-Aminophenyl)ethyl]amino}-1-phenylethanolhydrochloride
Packaging
5g
Price
$158
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA156821
Product name
(R)-2-((4-Aminophenethyl)amino)-1-phenylethanol hydrochloride
Packaging
25g
Price
$235
Updated
2021/12/16
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(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride Chemical Properties,Usage,Production

Uses

(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.

Synthesis


A mixture of (100 g) (R)-2-[2?ˉ -(4-nitrophenyl)ethyl]amino] -1 -phenylethanol monohydroch bride (prepared according to example Ib), methanol (2000 mL) and Raney Nickel (20 g, wet) was stirred under hydrogen pressure (60 psi) for 6 hrs. The reaction solution was filtered, and the filtrate was concentrated in vacuo. The residue was mixed with isopropanol (300 mL) and reaction mixture was heated to 78??C (?à2). The mixture was added to toluene (900 mL). The reaction mixture was gradually cooled to 28??C (?à2) and stirred at this temperature for 3 hrs. The solid obtained was filtered, washed with toluene and dried under vacuo at 48??C (?à2) to obtain (R)-2-[[2-(4-aminophenyl)ethyl]-amino]- I -phenylethanol monohydrochioride.Yield: 78.1 g (86.1%); Purity by HPLC: 99.14 %.

(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride Suppliers

Anhui Dexinjia Biopharm Co., Ltd
Tel
0531-82375878 15269101859
Email
2710825968@qq.com
Country
China
ProdList
303
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Suzhou Uugene Biopharma Co., Ltd.
Tel
0512-69561956 18015581618
Email
sales@uugene.com
Country
China
ProdList
87
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55
Nanjing Zhiyan Pharmaceutical Technology Co. Ltd.
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18602559219
Email
sales@zhiyanchem.com
Country
China
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108
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58
Henan Dongyao Pharmaceutical Technology Co., Ltd
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18519331287
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1751713684@qq.com
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China
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ZHIWE CHEMTECH CO LTD
Tel
021-20221225 13917446399
Fax
QQ:115820162
Email
sales@zhiwe.net
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China
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Hunan Hui Bai Shi Biotechnology Co., Ltd.
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0731-85526065 13308475853
Email
ivy@hnhbsj.com
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China
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Shanghai T&W Pharmaceutical Co., Ltd.
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+86 21 61551611
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+86 21 50676805
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China
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China Nobel Chem Co., Limited
Tel
+86(0)21 60484900
Fax
+86(0)21 60484900
Country
China
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764
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TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
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Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
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View Lastest Price from (alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride 521284-22-0
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-18
Hebei Yanxi Chemical Co., Ltd.
Product
(1R)-2-{[2-(4-Aminophenyl)ethyl]amino}-1-phenylethanol hydrochlor ide (1:1) 521284-22-0
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
100tons
Release date
2023-09-13
Hebei Kingfiner Technology Development Co.Ltd
Product
(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino] methyl]benzenemethanol hydrochloride 521284-22-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000KG
Release date
2024-04-22

521284-22-0, (alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochlorideRelated Search:


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