ChemicalBook > CAS DataBase List > (alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride

(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride

Product Name
(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride
CAS No.
521284-22-0
Chemical Name
(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride
Synonyms
Mirabegron INT 3;Mirabegron Impurity M;Mirabegron Impurity 3 HCl;DarunavirDiamino(2S,3S)Isomer;Mirabegron Impurity 20 Hydrochloride;(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]m;(R)-alpha-[[[2-(4-AMinophenyl)ethyl]aMino]Methyl];(R)-2-(4-aminophenethylamino)-1- Phenylethanol HCL;(R)-2-[2-(4-Amino-phenyl)-ethylamino]-1-phenyl-ethanol HCl;(R)--[[[2-(4-aminophenyl)ethyl]amino]methyl]-Benzenemethanol
CBNumber
CB22614397
Molecular Formula
C16H21ClN2O
Formula Weight
292.81
MOL File
521284-22-0.mol
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(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride Property

Density 
1145 at 20℃
vapor pressure 
0.015Pa at 25℃
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Powder
Stability:
Hygroscopic
LogP
-1.35 at 20℃ and pH5.79
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
A622675
Product name
(R)-2-((4-Aminophenethyl)amino)-1-phenylethanolHydrochloride
Packaging
50g
Price
$730
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA156821
Product name
(R)-2-((4-Aminophenethyl)amino)-1-phenylethanol hydrochloride
Packaging
10g
Price
$130
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA156821
Product name
(R)-2-((4-Aminophenethyl)amino)-1-phenylethanol hydrochloride
Packaging
5G
Price
$80
Updated
2021/12/16
AK Scientific
Product number
0031AP
Product name
(1R)-2-{[2-(4-Aminophenyl)ethyl]amino}-1-phenylethanolhydrochloride
Packaging
5g
Price
$158
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA156821
Product name
(R)-2-((4-Aminophenethyl)amino)-1-phenylethanol hydrochloride
Packaging
25g
Price
$235
Updated
2021/12/16
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(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride Chemical Properties,Usage,Production

Uses

(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.

Synthesis


A mixture of (100 g) (R)-2-[2?ˉ -(4-nitrophenyl)ethyl]amino] -1 -phenylethanol monohydroch bride (prepared according to example Ib), methanol (2000 mL) and Raney Nickel (20 g, wet) was stirred under hydrogen pressure (60 psi) for 6 hrs. The reaction solution was filtered, and the filtrate was concentrated in vacuo. The residue was mixed with isopropanol (300 mL) and reaction mixture was heated to 78??C (?à2). The mixture was added to toluene (900 mL). The reaction mixture was gradually cooled to 28??C (?à2) and stirred at this temperature for 3 hrs. The solid obtained was filtered, washed with toluene and dried under vacuo at 48??C (?à2) to obtain (R)-2-[[2-(4-aminophenyl)ethyl]-amino]- I -phenylethanol monohydrochioride.Yield: 78.1 g (86.1%); Purity by HPLC: 99.14 %.

(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride Suppliers

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View Lastest Price from (alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride 521284-22-0
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-18
Hebei Yanxi Chemical Co., Ltd.
Product
(1R)-2-{[2-(4-Aminophenyl)ethyl]amino}-1-phenylethanol hydrochlor ide (1:1) 521284-22-0
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
100tons
Release date
2023-09-13
Hebei Kingfiner Technology Development Co.Ltd
Product
(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino] methyl]benzenemethanol hydrochloride 521284-22-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000KG
Release date
2024-04-22

521284-22-0, (alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochlorideRelated Search:

(alphaR)-alpha-Hydroxy-N-[2-(4-nitrophenyl)ethyl]benzeneacetamide Mirabegron (alphaR)-alpha-[[[2-(4-Nitrophenyl)ethyl]amino]methyl]benzenemethanol BenzeneMethanol, -[[[2-(4-nitrophenyl)ethyl]aMino]Methyl]-, (R)-

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  • DarunavirDiamino(2S,3S)Isomer
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  • 521284-22-0
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