(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride
- Product Name
- (alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride
- CAS No.
- 521284-22-0
- Chemical Name
- (alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride
- Synonyms
- Mirabegron INT 3;Mirabegron Impurity M;Mirabegron Impurity 3 HCl;DarunavirDiamino(2S,3S)Isomer;Mirabegron Impurity 20 Hydrochloride;(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]m;(R)-alpha-[[[2-(4-AMinophenyl)ethyl]aMino]Methyl];(R)-2-(4-aminophenethylamino)-1- Phenylethanol HCL;(R)-2-[2-(4-Amino-phenyl)-ethylamino]-1-phenyl-ethanol HCl;(R)--[[[2-(4-aminophenyl)ethyl]amino]methyl]-Benzenemethanol
- CBNumber
- CB22614397
- Molecular Formula
- C16H21ClN2O
- Formula Weight
- 292.81
- MOL File
- 521284-22-0.mol
(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride Property
- Density
- 1145 at 20℃
- vapor pressure
- 0.015Pa at 25℃
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Powder
- Stability:
- Hygroscopic
- LogP
- -1.35 at 20℃ and pH5.79
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A622675
- Product name
- (R)-2-((4-Aminophenethyl)amino)-1-phenylethanolHydrochloride
- Packaging
- 50g
- Price
- $730
- Updated
- 2021/12/16
- Product number
- FA156821
- Product name
- (R)-2-((4-Aminophenethyl)amino)-1-phenylethanol hydrochloride
- Packaging
- 10g
- Price
- $130
- Updated
- 2021/12/16
- Product number
- FA156821
- Product name
- (R)-2-((4-Aminophenethyl)amino)-1-phenylethanol hydrochloride
- Packaging
- 5G
- Price
- $80
- Updated
- 2021/12/16
- Product number
- 0031AP
- Product name
- (1R)-2-{[2-(4-Aminophenyl)ethyl]amino}-1-phenylethanolhydrochloride
- Packaging
- 5g
- Price
- $158
- Updated
- 2021/12/16
- Product number
- FA156821
- Product name
- (R)-2-((4-Aminophenethyl)amino)-1-phenylethanol hydrochloride
- Packaging
- 25g
- Price
- $235
- Updated
- 2021/12/16
(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride Chemical Properties,Usage,Production
Uses
(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.
Synthesis
A mixture of (100 g) (R)-2-[2?ˉ -(4-nitrophenyl)ethyl]amino] -1 -phenylethanol monohydroch bride (prepared according to example Ib), methanol (2000 mL) and Raney Nickel (20 g, wet) was stirred under hydrogen pressure (60 psi) for 6 hrs. The reaction solution was filtered, and the filtrate was concentrated in vacuo. The residue was mixed with isopropanol (300 mL) and reaction mixture was heated to 78??C (?à2). The mixture was added to toluene (900 mL). The reaction mixture was gradually cooled to 28??C (?à2) and stirred at this temperature for 3 hrs. The solid obtained was filtered, washed with toluene and dried under vacuo at 48??C (?à2) to obtain (R)-2-[[2-(4-aminophenyl)ethyl]-amino]- I -phenylethanol monohydrochioride.Yield: 78.1 g (86.1%); Purity by HPLC: 99.14 %.
(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride Suppliers
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View Lastest Price from (alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride manufacturers
- Product
- (alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride 521284-22-0
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-18
- Product
- (1R)-2-{[2-(4-Aminophenyl)ethyl]amino}-1-phenylethanol hydrochlor ide (1:1) 521284-22-0
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 100tons
- Release date
- 2023-09-13
- Product
- (alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino] methyl]benzenemethanol hydrochloride 521284-22-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000KG
- Release date
- 2024-04-22