CB 30865

Product Name: CB 30865
CAS No.: 206275-15-2
Chemical Name: CB 30865
Synonyms: ZM242421;CB 30865;ZM-242421;ZM 242421;4-[[(7-Bromo-1,4-dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl]-2-propynylamino]-N-(3-pyridinylmethyl)benzamide;4-(((7-bromo-2-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)methyl)(prop-2-yn-1-yl)amino)-n-(pyridin-3-ylmethyl)benzamide;Benzamide, 4-[[(7-bromo-3,4-dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl]-2-propyn-1-ylamino]-N-(3-pyridinylmethyl)-
CBNumber: CB22627674
Molecular Formula: C26H22BrN5O2
Formula Weight: 516.38918
MOL File: 206275-15-2.mol

More

Less

CB 30865 Property

Density: 1.38±0.1 g/cm3(Predicted)
storage temp.: Store at 0-8 °C
solubility: DMSO : 33.33 mg/mL (64.54 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form: Powder
pka: 14.31±0.46(Predicted)
color: White to off-white

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

ChemScene

Product number: CS-1152
Product name: CB30865
Purity: 98.05%
Packaging: 5mg
Price: $343
Updated: 2021/12/16

ApexBio Technology

Product number: A3286
Product name: CB30865
Packaging: 5mg
Price: $419
Updated: 2021/12/16

ChemScene

Product number: CS-1152
Product name: CB30865
Purity: 98.05%
Packaging: 10mg
Price: $443
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0132427
Product name: 4-[[(7-BROMO-1,4-DIHYDRO-2-METHYL-4-OXO-6-QUINAZOLINYL)METHYL]-2-PROPYNYLAMINO]-N-(3-PYRIDINYLMETHYLBENZAMIDE
Purity: 95.00%
Packaging: 5MG
Price: $503.92
Updated: 2021/12/16

ApexBio Technology

Product number: A3286
Product name: CB30865
Packaging: 10mg
Price: $541
Updated: 2021/12/16

More

Less

CB 30865 Chemical Properties,Usage,Production

Uses

CB30865 (ZM 242421) is a nicotinamide phosphoribosyltransferase (Nampt) inhibitor, with potent cytotoxicity. CB30865 is highly potent against a variety of human tumour cell lines (IC50 values in the 1-10 nM range)[1][2]. CB30865 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

References

[1] Fleischer TC, et al. Chemical proteomics identifies Nampt as the target of CB30865, an orphan cytotoxic compound. Chem Biol. 2010 Jun 25;17(6):659-664. DOI:10.1016/j.chembiol.2010.05.008
[2] Skelton LA, et al. Cell cycle effects of CB30865, a lipophilic quinazoline-based analogue of the antifolate thymidylate synthase inhibitor ICI 198583 with an undefined mechanism of action. Cytometry. 1998 Sep 1;33(1):56-66. DOI:10.1002/(sici)1097-0320(19980901)33:13.0.co;2-9

CB 30865 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

CB 30865 Suppliers

China 38 United States 10 Global 48

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 12952
Advantage: 65

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

SPIRO PHARMA

Tel
Fax: -
Email: eric_feng1954@126.com
Country: China
ProdList: 9248
Advantage: 55

Codow Chemical Co.,Ltd.

Tel: 18620099427
Fax: +86-20-62619665
Email: amy@howeipharm.com
Country: China
ProdList: 6687
Advantage: 55

Guangzhou QiYun Biotechnology Co., Ltd.

Tel: 020-61288194 61288195
Fax: 020-61288700
Email: 505721671@qq.com
Country: China
ProdList: 3866
Advantage: 58

Chengdu Huachun Technology Co., Ltd

Tel: 400-1166-196 15982826727
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 14603
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4660
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

206275-15-2, CB 30865Related Search:

CB 30865

ZM 242421

ZM242421

ZM-242421

4-[[(7-Bromo-1,4-dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl]-2-propynylamino]-N-(3-pyridinylmethyl)benzamide

Benzamide, 4-[[(7-bromo-3,4-dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl]-2-propyn-1-ylamino]-N-(3-pyridinylmethyl)-

4-(((7-bromo-2-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)methyl)(prop-2-yn-1-yl)amino)-n-(pyridin-3-ylmethyl)benzamide

206275-15-2

C26H22BrN5O2