ChemicalBook > CAS DataBase List > SB408124 Hydrochloride

SB408124 Hydrochloride

Product Name
SB408124 Hydrochloride
CAS No.
1431697-90-3
Chemical Name
SB408124 Hydrochloride
Synonyms
SB-408124 HCl;SB408124 Hydrochloride;SB 408124 Hydrochloride;SB-408124 (Hydrochloride);SB 408124 HYDROCHLORIDE;SB408124 HYDROCHLORIDE;N-(6,8-Difluoro-2-methyl-4-quinolinyl)-N'-[4-(dimethylamino)phenyl]urea hydrochloride (1:1)
CBNumber
CB22666684
Molecular Formula
C19H19ClF2N4O
Formula Weight
392.8301664
MOL File
1431697-90-3.mol
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SB408124 Hydrochloride Property

storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
Powder
color 
White to gray
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-1073
Product name
SB-408124(Hydrochloride)
Purity
98.09%
Packaging
5mg
Price
$72
Updated
2021/12/16
ApexBio Technology
Product number
A3798
Product name
SB-408124Hydrochloride
Packaging
5mg
Price
$87
Updated
2021/12/16
Biosynth Carbosynth
Product number
FS159311
Product name
SB 408124 hydrochloride
Packaging
10mg
Price
$125
Updated
2021/12/16
ApexBio Technology
Product number
A3798
Product name
SB-408124Hydrochloride
Packaging
10mg
Price
$142
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611826
Product name
SB-408124 hydrochloride
Packaging
10mg
Price
$210.8
Updated
2021/12/16
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SB408124 Hydrochloride Chemical Properties,Usage,Production

Uses

SB 408124 Hydrochloride is a salt form of SB 40812 (S155088), which 4 is a novel OX-1 antagonist.

in vivo

SB-408124 reduces anxiety after psychotraumatic exposure. Predator induces acute psychotraumatic exposure decrease corticoliberin level in the rat's amygdala. Intranasal administration of SB-408124 restores it closely to normal and has an anxiolytic effect on animal behaviour[2].
Bilateral paraventricular nucleus microinjection of SB-408124 (30 pmol/50 nL per side) results in a greater reduction in mean arterial pressure (MAP) in high-salt intake (-16?mmHg) compared with NS-fed (-4?mmHg) anesthetized Dahl salt-sensitive rats[3].

IC 50

OX1 Receptor: 57 nM (Ki, in whole cell ); OX1 Receptor: 27 nM (Ki, in cell membrane)

SB408124 Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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SB408124 Hydrochloride Suppliers

China 29 United States 6 Global 35
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
SPIRO PHARMA
Tel
Fax
-
Email
eric_feng1954@126.com
Country
China
ProdList
9248
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Guangzhou QiYun Biotechnology Co., Ltd.
Tel
020-61288194 61288195
Fax
020-61288700
Email
505721671@qq.com
Country
China
ProdList
3866
Advantage
58
Shanghai SuperLan Chemcial Technique Centre
Tel
0-2022843681 15618226720
Fax
+86-21-51601218
Email
chaolaichem@foxmail.com
Country
China
ProdList
12476
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Musechem
Tel
+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
Country
United States
ProdList
4660
Advantage
60
Angel Pharmatech, Ltd.
Tel
17317130613
Fax
QQ3358272972
Email
3358272972@qq.com
Country
China
ProdList
3276
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58

1431697-90-3, SB408124 HydrochlorideRelated Search:


  • SB 408124 Hydrochloride
  • SB-408124 (Hydrochloride)
  • SB408124 Hydrochloride
  • N-(6,8-Difluoro-2-methyl-4-quinolinyl)-N'-[4-(dimethylamino)phenyl]urea hydrochloride (1:1)
  • SB-408124 HCl
  • SB 408124 HYDROCHLORIDE;SB408124 HYDROCHLORIDE
  • 1431697-90-3
  • C19H18F2N4OHCl