Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl-

Product Name: Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl-
CAS No.: 1017606-66-4
Chemical Name: Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl-
Synonyms: CS-1271;LPA2-IN-1;LPA2 antagonist 1;LPA-2 antagonist 1,LPA2 antagonist 1;N-[(2S)-1-[4-(3,4-Dichlorophenyl)sulfonylpiperazin-1-yl]propan-2-yl]-7-methylthieno[3,2-d]pyrimidin-4-amine;(S)-N-(1-(4-((3,4-Dichlorophenyl)sulfonyl)piperazin-1-yl)propan-2-yl)-7-methylthieno[3,2-d]pyrimidin-4-amine;Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl-
CBNumber: CB22668325
Molecular Formula: C20H23Cl2N5O2S2
Formula Weight: 500.46
MOL File: 1017606-66-4.mol

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Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl- Property

Boiling point:: 684.6±65.0 °C(Predicted)
Density: 1.453±0.06 g/cm3(Predicted)
storage temp.: 2-8°C(protect from light)
solubility: DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2)(1:2): 0.33 mg/ml
form: Powder
pka: 6.52±0.10(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 22051
Product name: LPA2 Antagonist 1
Purity: ≥98%
Packaging: 1mg
Price: $236
Updated: 2024/03/01

Cayman Chemical

Product number: 22051
Product name: LPA2 Antagonist 1
Purity: ≥98%
Packaging: 5mg
Price: $395
Updated: 2024/03/01

Cayman Chemical

Product number: 22051
Product name: LPA2 Antagonist 1
Purity: ≥98%
Packaging: 10mg
Price: $656
Updated: 2024/03/01

TRC

Product number: N926243
Product name: N-[(2S)-1-[4-(3,4-Dichlorophenyl)sulfonylpiperazin-1-yl]propan-2-yl]-7-methylthieno[3,2-d]pyrimidin-4-amine
Packaging: 5mg
Price: $350
Updated: 2021/12/16

ChemScene

Product number: CS-3103
Product name: LPA2antagonist1
Purity: 99.12%
Packaging: 5mg
Price: $420
Updated: 2021/12/16

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Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl- Chemical Properties,Usage,Production

Description

LPA₂ antagonist 1 is an antagonist of lysophosphatidic acid receptor 2 (LPA₂; IC₅₀ = 17 nM). It is selective for LPA₂ over LPA₁ and LPA₃ (IC₅₀s = >50 μM). LPA₂ antagonist 1 inhibits HGF-induced phosphorylation of ERK and proliferation of HCT116 colon cancer cells in a concentration-dependent manner.

Uses

N-[(2S)-1-[4-(3,4-Dichlorophenyl)sulfonylpiperazin-1-yl]propan-2-yl]-7-methylthieno[3,2-d]pyrimidin-4-amine is a Lpa2 protein antagonists.

Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl- Preparation Products And Raw materials

Raw materials

Preparation Products

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Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl- Suppliers

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1017606-66-4, Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl-Related Search:

CS-1271

LPA2-IN-1

Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl-

LPA2 antagonist 1

N-[(2S)-1-[4-(3,4-Dichlorophenyl)sulfonylpiperazin-1-yl]propan-2-yl]-7-methylthieno[3,2-d]pyrimidin-4-amine

(S)-N-(1-(4-((3,4-Dichlorophenyl)sulfonyl)piperazin-1-yl)propan-2-yl)-7-methylthieno[3,2-d]pyrimidin-4-amine

LPA-2 antagonist 1,LPA2 antagonist 1

1017606-66-4

C20H23Cl2N5O2S2