ChemicalBook > CAS DataBase List > BenzaMide, N-[4-chloro-3-(trifluoroMethyl)phenyl]-2-[2-(diMethylaMino)ethoxy]-6-ethoxy-
BenzaMide, N-[4-chloro-3-(trifluoroMethyl)phenyl]-2-[2-(diMethylaMino)ethoxy]-6-ethoxy-
- Product Name
- BenzaMide, N-[4-chloro-3-(trifluoroMethyl)phenyl]-2-[2-(diMethylaMino)ethoxy]-6-ethoxy-
- CAS No.
- 1311423-89-8
- Chemical Name
- BenzaMide, N-[4-chloro-3-(trifluoroMethyl)phenyl]-2-[2-(diMethylaMino)ethoxy]-6-ethoxy-
- Synonyms
- YF-2;YF 2;YF-2, 10 mM in DMSO;YF 2,HATs,inhibit,HAT,Histone Acetyltransferase,Inhibitor,YF2,YF-2;N-[4-chloro-3-(trifluoromethyl)phenyl]-2-[2-(dimethylamino)ethoxy]-6-ethoxybenzamide;BenzaMide, N-[4-chloro-3-(trifluoroMethyl)phenyl]-2-[2-(diMethylaMino)ethoxy]-6-ethoxy-
- CBNumber
- CB22668406
- Molecular Formula
- C20H22ClF3N2O3
- Formula Weight
- 430.85
- MOL File
- 1311423-89-8.mol
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BenzaMide, N-[4-chloro-3-(trifluoroMethyl)phenyl]-2-[2-(diMethylaMino)ethoxy]-6-ethoxy- Property
- Boiling point:
- 460.8±45.0 °C(Predicted)
- Density
- 1.285±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml
- form
- A crystalline solid
- pka
- 11.75±0.70(Predicted)
- color
- Light yellow to yellow
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0006379
- Product name
- YF-2
- Purity
- 99.36%
- Packaging
- 5mg
- Price
- $350
- Updated
- 2021/12/16
Apolloscientific
- Product number
- BISN0078
- Product name
- YF-2
- Purity
- 99%
- Packaging
- 5mg
- Price
- $464
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0006379
- Product name
- YF-2
- Purity
- 99.36%
- Packaging
- 10mg
- Price
- $550
- Updated
- 2021/12/16
Apolloscientific
- Product number
- BISN0078
- Product name
- YF-2
- Purity
- 99%
- Packaging
- 10mg
- Price
- $704
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0006379
- Product name
- YF-2
- Purity
- 99.36%
- Packaging
- 50mg
- Price
- $1650
- Updated
- 2021/12/16
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BenzaMide, N-[4-chloro-3-(trifluoroMethyl)phenyl]-2-[2-(diMethylaMino)ethoxy]-6-ethoxy- Chemical Properties,Usage,Production
Uses
YF-2 is an activator of histone acetyltransferase (HAT).
in vivo
YF-2 (20 mg/kg, 2 hours befor electric shock or 5 mg/kg, 30 min before the electric shock, i.p.) rescues the defect in contextual memory in mice, and shows no effect on contextual memory alone at 20 mg/kg in mice[1].
IC 50
GCN5/PCAF: 29.04 μM (EC50); GCN5: 49.31 μM (EC50); CBP: 2.75 μM (EC50)
BenzaMide, N-[4-chloro-3-(trifluoroMethyl)phenyl]-2-[2-(diMethylaMino)ethoxy]-6-ethoxy- Preparation Products And Raw materials
Raw materials
Preparation Products
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