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Sitagliptin DeaMino IMpurity 1

Product Name
Sitagliptin DeaMino IMpurity 1
CAS No.
1253056-18-6
Chemical Name
Sitagliptin DeaMino IMpurity 1
Synonyms
Sitagliptin FP Impurity D;Impurity FP-D;Sitagliptin iMpurity S;Sitagliptin Impurity 01;Sitagliptin Impurity 05;Sitagliptin Impurity FP-D;Sitagliptin EP Impurity 13;Sitagliptin EP Impurity FP-D;Sitagliptin DeaMino IMpurity 1;Sitagliptin Steryl acetyl Analog
CBNumber
CB22675695
Molecular Formula
C16H12F6N4O
Formula Weight
390.28
MOL File
1253056-18-6.mol
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Sitagliptin DeaMino IMpurity 1 Property

Boiling point:
517.5±60.0 °C(Predicted)
Density 
1.52±0.1 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol
pka
-0.06±0.20(Predicted)
form 
Solid
color 
Colourless to Pale Yellow Gel to Waxy
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
D281985
Product name
3-Desamino-2,3-dehydroSitagliptin
Packaging
50mg
Price
$1210
Updated
2021/12/16
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Sitagliptin DeaMino IMpurity 1 Chemical Properties,Usage,Production

Uses

3-Desamino-2,3-dehydro Sitagliptin is an impurity of Sitagliptin (S491000); a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.

Sitagliptin DeaMino IMpurity 1 Preparation Products And Raw materials

Raw materials

Preparation Products

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1253056-18-6, Sitagliptin DeaMino IMpurity 1Related Search:

BOC-(S)-3-AMINO-4-(2,4,5-TRIFLUORO-PHENYL)-BUTYRIC ACID Sitagliptin Sitagliptin Defuoro IMpurity 3 tert-Butyl ((R)-4-Oxo-4-(((R)-4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)amino)-1-(2,4,5-trifluorophenyl)butan-2-yl)carbamate 1,2,4-Triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione, 6,7,10,11-tetrahydro-3-(trifluoromethyl)-10-[(2,4,5-trifluorophenyl)methyl]- Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate 1,2,4-Triazolo[4,3-a]pyrazine, 7-[3-amino-1-oxo-4-(2,4,5-trifluorophenyl)-2-butenyl]-5,6,7,8-tetrahydro- 3-(trifluoromethyl)- (2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one Methyl 3-aMino-4-(2,4,5-trifluorophenyl)butanoate Sitagliptin IMpurity 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride Sitagliptin Impurity 34 Sitagliptin N-Phoshate IMpurity Sitagliptin impurity H HCl Sitagliptin Impurity 31 Sitagliptin phosphate Benzenebutanoicacid,b-aMino-2,4,5-trifluoro-,Methylester,(bR)- (R)-3-Amino-4-(2,4,5-trifluorophenyl)butyric acid

  • Sitagliptin DeaMino IMpurity 1
  • (E)-1-(3-(trifluoromethyl)-5,6-dihydro
  • Sitagliptin impurity 8/Sitagliptin FP Impurity D/3-Desamino-2,3-Dehydro Sitagliptin/(2E)-1-[3-(Trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)but-2-en-1-one
  • (2E)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one
  • 3-Desamino-2,3-dehydro Sitagliptin
  • Sitagliptin Impurity FP-D
  • (E)-1-(3-(trifluoroMethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)but-2-en-1-one
  • Sitagliptin iMpurity S
  • Sitagliptin phenyl crotonyl analog
  • Sitagliptin FP Impurity D
  • Impurity FP-D
  • Sitagliptin EP Impurity FP-D
  • Sitagliptin USPPhenylcrotonyl Analog
  • 2-Buten-1-one, 1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-, (2E)-
  • Sitagliptin EP Impurity 13
  • Sitagliptin Impurity 01
  • (E)-1-(3-(Trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)but-2-en-1-one (Sitagliptin Impurity)
  • Sitagliptin Phenylcrotonyl Analog/Sitagliptin FP Impurity D
  • Sitagliptin Phenylcrotonyl Analog (Sitagliptin FP Impurity D/ 3-Desamino-2,3-Dehydro Sitagliptin)
  • Sitagliptin Steryl acetyl Analog
  • SITAGLIPTIN STYRYLACETYL IMPURITY
  • Sitagliptin Tablets EP Impurity FP-D
  • Sitagliptin Impurity 17 (Sitagliptin Tablets EP Impurity FP-D)
  • Sitagliptin Impurity 05
  • (2E)-1-[3-(Trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)but-2-en-1-one
  • Sitagliptin FP Impurity D / Sitagliptin Phenylcrotonyl Analog (USP)
  • 1253056-18-6