TiMolol IMpurity E

Product Name: TiMolol IMpurity E
CAS No.: 1026075-53-5
Chemical Name: TiMolol IMpurity E
Synonyms: TiMolol IMpurity E;Timolol EP Impurity E;Timolol Maleate EP Impurity E;Timolol EP Impurity E/ Timolol Related Compound E;Timolol EP Impurity E (Timolol USP Related Compound E (Free Form));(S)-3-(tert-Butylamino)-1-(4-morpholino-1,2,5-thiadiazol-3-yloxy)propan-2-yl hydrogen maleate;(2Z)-4-[(1S)-1-[[(1,1-Dimethylethyl)-amino]methyl]-2-[[4-(morpholin-4-yl)-1,2,5-thia-diazol-3-yl]oxy;(S,Z)-4-((1-(tert-Butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid;(Z)-4-[(2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-yl]oxy-4-oxobut-2-enoic acid;(2Z)-4-[(1S)-1-[[(1,1-Dimethylethyl)amino]methyl]-2-[[4-(morpholin-4-yl)-1,2,5- thiadiazol-3-yl]oxy]ethoxy]-4-oxobut-2-enoic Acid
CBNumber: CB22675882
Molecular Formula: C17H26N4O6S
Formula Weight: 414.48
MOL File: 1026075-53-5.mol

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TiMolol IMpurity E Property

Boiling point:: 618.1±55.0 °C(Predicted)
Density: 1.300±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
pka: 2.31±0.25(Predicted)
Appearance: White to off-white Solid
Major Application: pharmaceutical (small molecule)
InChI: 1S/C17H26N4O6S/c1-17(2,3)18-10-12(27-14(24)5-4-13(22)23)11-26-16-15(19-28-20-16)21-6-8-25-9-7-21/h4-5,12,18H,6-11H2,1-3H3,(H,22,23)/b5-4-/t12-/m0/s1
InChIKey: MGIAXRFZDNBKRF-RXNFCKPNSA-N
SMILES: [s]1nc(c(n1)OC[C@@H](OC(=O)\C=C/C(=O)O)CNC(C)(C)C)N2CCOCC2

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Safety

WGK Germany: WGK 3
Storage Class: 11 - Combustible Solids
Hazard Classifications: Acute Tox. 4 Oral

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H302Harmful if swallowed

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0027958
Product name: TIMOLOL IMPURITY E
Purity: 95.00%
Packaging: 5MG
Price: $452.02
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 74784
Product name: TimololimpurityE
Packaging: 10mg
Price: $1190
Updated: 2021/12/16

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TiMolol IMpurity E Chemical Properties,Usage,Production

Uses

1-[(1S)-1-[[(1,1-Dimethylethyl)amino]methyl]-2-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]ethyl] Ester (2Z)-2-Butenedioic Acid (Timolol EP Impurity E; Timolol BP Impurity E; Timolol USP Related Compound E) is an impurity of Timolol (T4437005), an adrenergic blocking agent (1); antiarrhythmic (class II); antianginal; antiglaucoma (2) and antihypertensive (3) agent.

TiMolol IMpurity E Preparation Products And Raw materials

Raw materials

Preparation Products

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TiMolol IMpurity E Suppliers

China 40 India 4 United States 2 Global 46

S.Z. PhyStandard Bio-Tech. Co., Ltd.

Tel: 0755-83725681-603
Fax: +86 755 28094224
Country: China
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Quality Control Solutions Ltd.

Tel: 0755-66853366 13670046396
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Country: China
ProdList: 18421
Advantage: 56

Shenzhen SUNGENING Bio-Medical Co., Ltd.

Tel: 0755-28967200 13631290199
Fax: 0755-28967200
Email: wxf@sungening.com
Country: China
ProdList: 9629
Advantage: 60

Beijing Ditai Pharmaceutical Technology Co., Ltd.

Tel: 010-13810111756 13810111756
Fax: 13810111756
Email: 1601345388@qq.com
Country: China
ProdList: 302
Advantage: 58

CR Corporation Limited

Tel: +8613062833949
Email: fred.wen@crcorporation.cn
Country: China
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Advantage: 58

sgtlifesciences pvt ltd

Tel: +8617013299288
Email: dj@sgtlifesciences.com
Country: China
ProdList: 12373
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Guangzhou Dreampharm Biotechnology Co., Ltd.

Tel: 18689416704
Fax: QQ 3008233717
Email: angelng@dmstandards.com
Country: China
ProdList: 9927
Advantage: 12

Standardpharm Co. Ltd.

Tel: 86-714-3992388
Email: overseasales1@yongstandards.com
Country: United States
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Hefei fuya biotechnology co. LTD

Tel: 18096409024
Email: sales02@foreversyn.com
Country: China
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Cato Research Chemicals Inc.

Tel: +86-020-81960175-877 4000-868-328
Email: tianwen.zhan@cato-chem.com
Country: United States
ProdList: 10404
Advantage: 58

1026075-53-5, TiMolol IMpurity ERelated Search:

Bicyclo[3.2.0]hept-3-ene-6-acetic acid, 6-(aminomethyl)-3-ethyl-, 1,1-dimethylethyl ester, (1R,5S,6S)- ((1S,5R,6R)-6-Aminomethyl-3-ethylbicyclo[3.2.0]hept-3-en-6-yl)acetic acid tert-butyl ester Timolol EP Impurity G Timolol EP Impurity H 3-Chloro-4-morpholino-1,2,5-thiadiazole (+)-1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol (S)-Timolol maleate 4-MORPHOLIN-4-YL-1,2,5-THIADIAZOL-3-OL 1-Propanol,3-[(1,1-dimethylethyl)amino]-2-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]-oxy]- Timolol

TiMolol IMpurity E

Timolol EP Impurity E

(Z)-4-[(2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-yl]oxy-4-oxobut-2-enoic acid

Timolol Maleate EP Impurity E

(S)-3-(tert-Butylamino)-1-(4-morpholino-1,2,5-thiadiazol-3-yloxy)propan-2-yl hydrogen maleate

2-Butenedioic acid (2Z)-, 1-[(1S)-1-[[(1,1-dimethylethyl)amino]methyl]-2-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]ethyl] ester

1-?[(1S)?-?1-?[[(1,?1-?Dimethylethyl)?amino]?methyl]?-?2-?[[4-?(4-?morpholinyl)?-?1,?2,?5-?thiadiazol-?3-?yl]?oxy]?ethyl] Ester (2Z)?-?2-?Butenedioic Acid DISCONTINUED

Timolol EP Impurity E/ Timolol Related Compound E

(2Z)-4-[(1S)-1-[[(1,1-Dimethylethyl)amino]methyl]-2-[[4-(morpholin-4-yl)-1,2,5- thiadiazol-3-yl]oxy]ethoxy]-4-oxobut-2-enoic Acid

(S,Z)-4-((1-(tert-Butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid (Timolol Impurity)

(S,Z)-4-((1-(tert-Butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid

(2Z)-4-[(1S)-1-[[(1,1-Dimethylethyl)-amino]methyl]-2-[[4-(morpholin-4-yl)-1,2,5-thia-diazol-3-yl]oxy

Timolol EP Impurity E (Timolol USP Related Compound E (Free Form))

1026075-53-5

C17H26N4O6S