ChemicalBook > CAS DataBase List > Flupyradifurone

Flupyradifurone

Product Name
Flupyradifurone
CAS No.
951659-40-8
Chemical Name
Flupyradifurone
Synonyms
lupyradifurone;Flupyradifurone;Flupyradifurone Solution;Flupyradifurone in Acetonitrile;Flupyradifurone 100 μg/ml Acetonitrile;4-[(6-Chloro-3-pyridylmethyl)(2,2-difluoroethyl)amino]furan-2(5H)-one;4-(((6-Chloropyridin-3-yl)methyl)(2,2-difluoroethyl)amino)furan-2(5H)-one;2(5H)-Furanone, 4-[[(6-chloro-3-pyridinyl)methyl](2,2-difluoroethyl)amino]-;4-{[(6-chloropyridin-3-yl)methyl](2,2-difluoroethyl) amino}-2,5-dihydrofuran-2-one
CBNumber
CB22695888
Molecular Formula
C12H11ClF2N2O2
Formula Weight
288.68
MOL File
951659-40-8.mol
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Flupyradifurone Property

Melting point:
69 - 71°C
Boiling point:
457.7±45.0 °C(Predicted)
Density 
1.41±0.1 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
DMSO (Slightly, Sonicated), Methanol (Slightly)
pka
0.22±0.10(Predicted)
form 
Solid
color 
White to Pale Brown
BRN 
19518067
LogP
1.110 (est)
EPA Substance Registry System
2(5H)-Furanone, 4-[[(6-chloro-3-pyridinyl)methyl](2,2-difluoroethyl)amino]- (951659-40-8)
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Safety

Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
2
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H373May cause damage to organs through prolonged or repeated exposure

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P314Get medical advice/attention if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
37050
Product name
Flupyradifurone
Purity
PESTANAL
Packaging
100mg
Price
$500
Updated
2024/03/01
TRC
Product number
F598615
Product name
Flupyradifurone
Packaging
1mg
Price
$120
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
46297
Product name
Flupyradifurone
Packaging
10mg
Price
$650
Updated
2021/12/16
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Flupyradifurone Chemical Properties,Usage,Production

Description

Flupyradifurone(FPF) is a novel butenolide insecticide developed for foliar, soil and seed treatment applications (Nauen et al., 2015). FPF was commercially introduced to the market in 2014 as an integrated pest management (IPM)-friendly tool (Bordini et al., 2021), and is registered for use in a wide variety of fruit and vegetable crops and defined broad acre crops. It targets some of the world′s most destructive sucking pests including aphids, psyllids, scales, leafhoppers, mealy bugs, and is particularly important for the control of whiteflies such as Bemisia tabaci, a vector of serious phytopathogenic viruses such as tomato yellow leaf curl virus and cucurbit yellow stunting disorder virus (Castle et al., 2017; Roditakis et al., 2017).

Uses

Flupyradifurone is the first member of butenolide class of insecticides. Its mode of action is similar to neonicotinoid insecticides that act on the central nervous system of target insect pests as an agonist of the nicotinic acetylcholine receptor (nAChR). However, its chemical structure differs from the nitroguanidine neonicotinoids and thus it is a separate sub-class of IRAC Group 4. Flupyradifurone is a systemic insecticide and targets piercing, sucking insects such as aphids and whiteflies. The EPA has registered flupyradifurone on berries (except cranberry), cereal grains (except rice), alfalfa, clover, and vegetables (except sugar beet), fruits, and ornamental plants. On soybean flupyradifuron is registered for foliar and seed treatment use only. Flupyradifurone is formulated as soluble liquid (SL) and flowable concentrate (FS). Application to soybean seeds is approved via commercial seed treatment application only.

Definition

ChEBI: Flupyradifurone is a tertiary amino compound that is ammonia in which the nitrogens have been replaced by (6-chloropyridin-3-yl)methyl, 2,2-difluoroethyl, and 5-oxo-2,5-dihydrofuran-3-yl groups, respectively. A nicotinic acetylcholine receptor (AChR) agonist, it is used as an insecticide to control sucking pests in a variety of crops. It has a role as a nicotinic acetylcholine receptor agonist and an insecticide. It is a butenolide, a monochloropyridine, an organofluorine insecticide, an enamine and a tertiary amino compound.

Preparation

Two different pathways for the synthesis of flupyradifurone
Starting from tetronic acid, one approach consists in two consecutive reactions. Where the tetronic acid reacts firstly with a difluoroethane-1-amine and secondly with 2-Chloro-5- (chloromethyl)pyridine.

And the other approach, where the tetronic acid reacts with difluoroethane-1-amine derivative in the presence of 4-toluenesulfonic acid in a “one pot” approach to yield flupyradifurone.

Flupyradifurone Preparation Products And Raw materials

Raw materials

Preparation Products

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Flupyradifurone Suppliers

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View Lastest Price from Flupyradifurone manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Flupyradifurone 951659-40-8
Price
US $0.00-0.00/Kg
Min. Order
1KG
Purity
99.0%
Supply Ability
500 tons
Release date
2020-04-26

951659-40-8, FlupyradifuroneRelated Search:


  • Flupyradifurone
  • 4-[(6-Chloro-3-pyridylmethyl)(2,2-difluoroethyl)amino]furan-2(5H)-one
  • Flupyradifurone Solution
  • 2(5H)-Furanone, 4-[[(6-chloro-3-pyridinyl)methyl](2,2-difluoroethyl)amino]-
  • 4-{[(6-chloropyridin-3-yl)methyl](2,2-difluoroethyl) amino}-2,5-dihydrofuran-2-one
  • 4-(((6-Chloropyridin-3-yl)methyl)(2,2-difluoroethyl)amino)furan-2(5H)-one
  • lupyradifurone
  • Flupyradifurone 100 μg/ml Acetonitrile
  • Flupyradifurone in Acetonitrile
  • 951659-40-8
  • C12H11ClF2N2O2
  • Amines, Aromatics, Heterocycles
  • chem