ChemicalBook > CAS DataBase List > 4-[(AMinocarbonyl)aMino]-N-[(9H-fluoren-9-ylMethoxy)carbonyl]-D-phenylalanine

4-[(AMinocarbonyl)aMino]-N-[(9H-fluoren-9-ylMethoxy)carbonyl]-D-phenylalanine

Product Name
4-[(AMinocarbonyl)aMino]-N-[(9H-fluoren-9-ylMethoxy)carbonyl]-D-phenylalanine
CAS No.
324017-22-3
Chemical Name
4-[(AMinocarbonyl)aMino]-N-[(9H-fluoren-9-ylMethoxy)carbonyl]-D-phenylalanine
Synonyms
Fmoc-D-Aph(Cbm)-OH;FMoc-D-4-Aph(CbM)-OH;(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-ureidophenyl)propanoic acid;Fmoc-D-Aph(Cbm);Fmoc-D-4-Aph(cbm);Fmoc-4-Aph(Trt)-OH;Fmoc-D-Phe(4-[(NH2CO)NH2])-OH;(9H-Fluoren-9-yl)MethOxy]Carbonyl D-Aph(Cbm)-OH;4-[(Aminocarbonyl)amino]-N-Fmoc-D-phenylalanine;4-[(AMinocarbonyl)aMino]-N-[(9H-fluoren-9-ylMethoxy)carbonyl]-D-phenylalanine
CBNumber
CB22705259
Molecular Formula
C25H23N3O5
Formula Weight
445.47
MOL File
324017-22-3.mol
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4-[(AMinocarbonyl)aMino]-N-[(9H-fluoren-9-ylMethoxy)carbonyl]-D-phenylalanine Property

Melting point:
163℃ (decomposition)
Boiling point:
699.1±55.0 °C(Predicted)
Density 
1.376±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
pka
3.82±0.10(Predicted)
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic
InChIKey
HFPDOFBZCSQAEJ-JOCHJYFZSA-N
SMILES
C(O)(=O)[C@@H](CC1=CC=C(NC(N)=O)C=C1)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
A602868
Product name
(2R)-3-[4-(carbamoylamino)phenyl]-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoicAcid
Packaging
50mg
Price
$45
Updated
2021/12/16
ChemPep
Product number
180197
Product name
Fmoc-D-Aph(Cbm)-OH
Packaging
1g
Price
$200
Updated
2021/12/16
ChemScene
Product number
CS-0037288
Product name
(2R)-3-[4-(carbamoylamino)phenyl]-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoicacid
Packaging
100mg
Price
$514
Updated
2021/12/16
ChemPep
Product number
180197
Product name
Fmoc-D-Aph(Cbm)-OH
Packaging
5g
Price
$600
Updated
2021/12/16
ChemScene
Product number
CS-0037288
Product name
(2R)-3-[4-(carbamoylamino)phenyl]-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoicacid
Packaging
250mg
Price
$856
Updated
2021/12/16
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4-[(AMinocarbonyl)aMino]-N-[(9H-fluoren-9-ylMethoxy)carbonyl]-D-phenylalanine Chemical Properties,Usage,Production

Uses

Fmoc-D-4-Aph(cBm)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize biologically active peptide mimetics, such as Ac-D2Nal-D4Cpa-D3Pal-Ser-4Aph/4Amf(P)-D4Aph/D4Amf(Q)-Leu-ILys-Pro-DAla-NH2 with gonadotropin-releasing hormone (GnRH) antagonist activity[1].

References

[1] Guangcheng Jiang, et al. "GnRH antagonists: a new generation of long acting analogues incorporating p-ureido-phenylalanines at positions 5 and 6." Journal of medicinal chemistry 44.3 (2001): 453-467. DOI:10.1021/jm0003900

4-[(AMinocarbonyl)aMino]-N-[(9H-fluoren-9-ylMethoxy)carbonyl]-D-phenylalanine Preparation Products And Raw materials

Raw materials

Preparation Products

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4-[(AMinocarbonyl)aMino]-N-[(9H-fluoren-9-ylMethoxy)carbonyl]-D-phenylalanine Suppliers

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View Lastest Price from 4-[(AMinocarbonyl)aMino]-N-[(9H-fluoren-9-ylMethoxy)carbonyl]-D-phenylalanine manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
4-[(AMinocarbonyl)aMino]-N-[(9H-fluoren-9-ylMethoxy)carbonyl]-D-phenylalanine 324017-22-3
Price
US $0.10/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
1000 tons
Release date
2020-04-24
Hebei Mingeng Biotechnology Co., Ltd
Product
Fmoc-D-Aph(Cbm)-OH 324017-22-3
Price
US $150.00/ASSAYS
Min. Order
10g
Purity
more than 99.6%
Supply Ability
500kg/month
Release date
2021-11-30
Career Henan Chemical Co
Product
4-[(AMinocarbonyl)aMino]-N-[(9H-fluoren-9-ylMethoxy)carbonyl]-D-phenylalanine 324017-22-3
Price
US $1.00/ASSAYS
Min. Order
1ASSAYS
Purity
99.99%
Supply Ability
200kg
Release date
2019-12-20

324017-22-3, 4-[(AMinocarbonyl)aMino]-N-[(9H-fluoren-9-ylMethoxy)carbonyl]-D-phenylalanineRelated Search:


  • Fmoc-D-Aph(Cbm)-OH
  • 4-[(AMinocarbonyl)aMino]-N-[(9H-fluoren-9-ylMethoxy)carbonyl]-D-phenylalanine
  • FMoc-D-4-Aph(CbM)-OH
  • (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-ureidophenyl)propanoic acid
  • Fmoc-4-Aph(Trt)-OH
  • (9H-Fluoren-9-yl)MethOxy]Carbonyl D-Aph(Cbm)-OH
  • Fmoc-D-4-Aph(cbm)
  • (2R)-3-[4-(carbamoylamino)phenyl]-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
  • D-Phenylalanine, 4-[(aminocarbonyl)amino]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
  • 4-[(Aminocarbonyl)amino]-N-Fmoc-D-phenylalanine
  • Fmoc-D-Aph(Cbm)
  • Fmoc-D-Phe(4-[(NH2CO)NH2])-OH
  • 324017-22-3