FluoroMethyl 2-pyridyl sulfone
- Product Name
- FluoroMethyl 2-pyridyl sulfone
- CAS No.
- 1365765-53-2
- Chemical Name
- FluoroMethyl 2-pyridyl sulfone
- Synonyms
- FM-2-pyridyl sulfone;2-Pyridyl fluoromethyl sulfone;FluoroMethyl 2-pyridyl sulfone;2-[(Fluoromethyl)sulfonyl]-pyridine;Pyridine, 2-[(fluoromethyl)sulfonyl]-;Pyridine, 2-[(fluoromethyl)sulfonyl]-2-fluoromethanesulfonylpyridine
- CBNumber
- CB22709646
- Molecular Formula
- C6H6FNO2S
- Formula Weight
- 175.18
- MOL File
- 1365765-53-2.mol
FluoroMethyl 2-pyridyl sulfone Property
- Boiling point:
- 353.2±35.0 °C(Predicted)
- Density
- 1.348±0.06 g/cm3(Predicted)
- pka
- -3.04±0.19(Predicted)
Safety
- Safety Statements
- 24/25
- HS Code
- 29309090
N-Bromosuccinimide Price
- Product number
- JK1711631
- Product name
- Fluoromethyl2-pyridylsulfone
- Purity
- 98%
- Packaging
- 250mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- PC10695
- Product name
- Fluoromethyl2-pyridylsulfone
- Purity
- 95%
- Packaging
- 250mg
- Price
- $104
- Updated
- 2021/12/16
- Product number
- JK1711631
- Product name
- Fluoromethyl2-pyridylsulfone
- Purity
- 98%
- Packaging
- 1g
- Price
- $178
- Updated
- 2021/12/16
- Product number
- PC10695
- Product name
- Fluoromethyl2-pyridylsulfone
- Purity
- 95%
- Packaging
- 1g
- Price
- $320
- Updated
- 2021/12/16
FluoroMethyl 2-pyridyl sulfone Chemical Properties,Usage,Production
Description
Fluoromethyl 2-pyridyl sulfone and its derivatives can be used as novel monofluoromethylation reagents. The monofluorinated sulfinate intermediates during the monofluoroolefination of aldehydes and ketones can be halogenated in situ to afford mono- and dihalofluoroalkyl compounds. The coupling reaction between iodofluoromethyl 2-pyridyl sulfone and aryl iodides mediated by copper can be used to prepare monofluoromethyl arenes and heteroarenes.
Chemical Properties
white solid
Reactions
(1) Dihalofluoromethylation of aldehydes and ketones.
(3) Monofluoromethylation of arenes and heteroarenes.
References
[1] YANCHUAN ZHAO Jinbo H Bing Gao. From Olefination to Alkylation: In-Situ Halogenation of Julia–Kocienski Intermediates Leading to Formal Nucleophilic Iodo- and Bromodifluoromethylation of Carbonyl Compounds[J]. Journal of the American Chemical Society, 2012, 134 13: 5790-5793. DOI:10.1021/ja301601b.
[2] YANCHUAN ZHAO. Copper-Mediated Fluoroalkylation of Aryl Iodides Enables Facile Access to Diverse Fluorinated Compounds: The Important Role of the (2-Pyridyl)sulfonyl Group[J]. Organic Letters, 2012, 14 23: 6080-6083. DOI:10.1021/ol3029737.
FluoroMethyl 2-pyridyl sulfone Preparation Products And Raw materials
Raw materials
Preparation Products
FluoroMethyl 2-pyridyl sulfone Suppliers
- Tel
- +1-858-6993322
- Fax
- (+1)-858-876-1948
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- United States
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View Lastest Price from FluoroMethyl 2-pyridyl sulfone manufacturers
- Product
- FluoroMethyl 2-pyridyl sulfone 1365765-53-2
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-09