ChemicalBook > CAS DataBase List > CID 797718

CID 797718

Product Name: CID 797718
CAS No.: 370586-05-3
Chemical Name: CID 797718
Synonyms: CS-1341;CID 797718;CID 797718, >=98%;CID-797718;CID797718;CID 797718, 370586-05-3;CID-797718, 10 mM in DMSO;CID797718,inhibit,CID-797718,Inhibitor;9-Hydroxy-1H,2H,3H,4H-chromeno[3,4-b]pyridin-5-one;9-HYDROXY-1,2,3,4-TETRAHYDROCHROMENO[3,4-B]PYRIDIN-5-ONE;9-HYDROXY-3,4-DIHYDRO-1H-CHROMENO[3,4-B]PYRIDIN-5(2H)-ONE
CBNumber: CB22716547
Molecular Formula: C12H11NO3
Formula Weight: 217.22
MOL File: 370586-05-3.mol

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CID 797718 Property

Melting point:: 213-216 °C(Solv: isopropanol (67-63-0))
Boiling point:: 517.6±50.0 °C(Predicted)
Density: 1.43±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 1 mg/ml
form: A crystalline solid
pka: 9.39±0.20(Predicted)
color: Light brown to brown

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 23428
Product name: CID797718
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 23428
Product name: CID797718
Purity: ≥98%
Packaging: 5mg
Price: $139
Updated: 2024/03/01

Cayman Chemical

Product number: 23428
Product name: CID797718
Purity: ≥98%
Packaging: 10mg
Price: $243
Updated: 2024/03/01

Cayman Chemical

Product number: 23428
Product name: CID797718
Purity: ≥98%
Packaging: 25mg
Price: $533
Updated: 2024/03/01

AK Scientific

Product number: 7082CD
Product name: 9-Hydroxy-1,2,3,4-tetrahydrochromeno[3,4-b]pyridin-5-one
Packaging: 1mg
Price: $133
Updated: 2021/12/16

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CID 797718 Chemical Properties,Usage,Production

Description

CID797718 is a protein kinase D1 (PKD1) inhibitor (IC₅₀ = 7 μM). It also inhibits CDK activating kinase (CAK) and polo-like kinase 1 (PLK1) but has no activity at AKT (IC₅₀s = 8.4, 21.9, and >50 μM, respectively). CID797718 inhibits PKD1 activity in LNCaP cells with an IC₅₀ value of 0.21 μM. CID797718 is a byproduct in the synthesis of CID755673 .

Uses

CID-797718 is a compound with ambiguous properties.

References

[1] ELIZABETH R SHARLOW. Potent and selective disruption of protein kinase D functionality by a benzoxoloazepinolone.[J]. The Journal of Biological Chemistry, 2008, 283 48: 33516-33526. DOI: 10.1074/jbc.m805358200
[2] COURTNEY R LAVALLE. Novel protein kinase D inhibitors cause potent arrest in prostate cancer cell growth and motility.[J]. BMC chemical biology, 2010, 10: 5. DOI: 10.1186/1472-6769-10-5

CID 797718 Preparation Products And Raw materials

Raw materials

Preparation Products

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CID 797718 Suppliers

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370586-05-3, CID 797718Related Search:

9-HYDROXY-3,4-DIHYDRO-1H-CHROMENO[3,4-B]PYRIDIN-5(2H)-ONE

CID 797718

CID 797718, >=98%

CID-797718;CID797718

CS-1341

CID 797718, 370586-05-3

9-HYDROXY-1,2,3,4-TETRAHYDROCHROMENO[3,4-B]PYRIDIN-5-ONE

9-Hydroxy-1H,2H,3H,4H-chromeno[3,4-b]pyridin-5-one

CID797718,inhibit,CID-797718,Inhibitor

9-Hydroxy-1,2,3,4-tetrahydro-5H-chromeno[3,4-b]pyridin-5-one

5H-[1]Benzopyrano[3,4-b]pyridin-5-one, 1,2,3,4-tetrahydro-9-hydroxy-

CID-797718, 10 mM in DMSO

370586-05-3

Inhibitors