ChemicalBook > CAS DataBase List > CID 797718

CID 797718

Product Name
CID 797718
CAS No.
370586-05-3
Chemical Name
CID 797718
Synonyms
CS-1341;CID 797718;CID 797718, >=98%;CID-797718;CID797718;CID 797718, 370586-05-3;CID-797718, 10 mM in DMSO;CID797718,inhibit,CID-797718,Inhibitor;9-Hydroxy-1H,2H,3H,4H-chromeno[3,4-b]pyridin-5-one;9-HYDROXY-1,2,3,4-TETRAHYDROCHROMENO[3,4-B]PYRIDIN-5-ONE;9-HYDROXY-3,4-DIHYDRO-1H-CHROMENO[3,4-B]PYRIDIN-5(2H)-ONE
CBNumber
CB22716547
Molecular Formula
C12H11NO3
Formula Weight
217.22
MOL File
370586-05-3.mol
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CID 797718 Property

Melting point:
213-216 °C(Solv: isopropanol (67-63-0))
Boiling point:
517.6±50.0 °C(Predicted)
Density 
1.43±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 1 mg/ml
form 
A crystalline solid
pka
9.39±0.20(Predicted)
color 
Light brown to brown
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
23428
Product name
CID797718
Purity
≥98%
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
23428
Product name
CID797718
Purity
≥98%
Packaging
5mg
Price
$139
Updated
2024/03/01
Cayman Chemical
Product number
23428
Product name
CID797718
Purity
≥98%
Packaging
10mg
Price
$243
Updated
2024/03/01
Cayman Chemical
Product number
23428
Product name
CID797718
Purity
≥98%
Packaging
25mg
Price
$533
Updated
2024/03/01
AK Scientific
Product number
7082CD
Product name
9-Hydroxy-1,2,3,4-tetrahydrochromeno[3,4-b]pyridin-5-one
Packaging
5mg
Price
$252
Updated
2021/12/16
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CID 797718 Chemical Properties,Usage,Production

Description

CID797718 is a protein kinase D1 (PKD1) inhibitor (IC50 = 7 μM). It also inhibits CDK activating kinase (CAK) and polo-like kinase 1 (PLK1) but has no activity at AKT (IC50s = 8.4, 21.9, and >50 μM, respectively). CID797718 inhibits PKD1 activity in LNCaP cells with an IC50 value of 0.21 μM. CID797718 is a byproduct in the synthesis of CID755673 .

Uses

CID-797718 is a compound with ambiguous properties.

References

[1] ELIZABETH R SHARLOW. Potent and selective disruption of protein kinase D functionality by a benzoxoloazepinolone.[J]. The Journal of Biological Chemistry, 2008, 283 48: 33516-33526. DOI: 10.1074/jbc.m805358200
[2] COURTNEY R LAVALLE. Novel protein kinase D inhibitors cause potent arrest in prostate cancer cell growth and motility.[J]. BMC chemical biology, 2010, 10: 5. DOI: 10.1186/1472-6769-10-5

CID 797718 Preparation Products And Raw materials

Raw materials

Preparation Products

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CID 797718 Suppliers

A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58

370586-05-3, CID 797718Related Search:


  • 9-HYDROXY-3,4-DIHYDRO-1H-CHROMENO[3,4-B]PYRIDIN-5(2H)-ONE
  • CID 797718
  • CID 797718, >=98%
  • CID-797718;CID797718
  • CS-1341
  • CID 797718, 370586-05-3
  • 9-HYDROXY-1,2,3,4-TETRAHYDROCHROMENO[3,4-B]PYRIDIN-5-ONE
  • 9-Hydroxy-1H,2H,3H,4H-chromeno[3,4-b]pyridin-5-one
  • CID797718,inhibit,CID-797718,Inhibitor
  • 9-Hydroxy-1,2,3,4-tetrahydro-5H-chromeno[3,4-b]pyridin-5-one
  • 5H-[1]Benzopyrano[3,4-b]pyridin-5-one, 1,2,3,4-tetrahydro-9-hydroxy-
  • CID-797718, 10 mM in DMSO
  • 370586-05-3
  • Inhibitors