DSPE-PEG-NH2
- Product Name
- DSPE-PEG-NH2
- CAS No.
- 474922-26-4
- Chemical Name
- DSPE-PEG-NH2
- Synonyms
- DSPE-PEG2000-NH2;DSPE-PEG(2000) Amine;DSPE-PEG-2K-Amine;NH2-PEG-DSPE;DSPE-PEG-NH2;DSPE-PEG2k-NH2;DSPE-PEG1000-SH;DSPE-PEG-NH2 ammonium Salt;DSPE-PEG-SH/ DSPE-PEG-Thiol;DSPE-PEG-SH,CAS:474922-26-4
- CBNumber
- CB22720614
- Molecular Formula
- (C2H4O)nC44H87N2O10P.H3N
- Formula Weight
- 0
- MOL File
- 474922-26-4.mol
DSPE-PEG-NH2 Property
- storage temp.
- Store at -20°C
- solubility
- DMF: 11 mg/ml,Ethanol: 20 mg/ml
- form
- Solid
- color
- White to off-white
- InChIKey
- AXHRCGLQEUQOIS-UHFFFAOYSA-N
- SMILES
- C(COC(=O)CCCCCCCCCCCCCCCCC)(OC(=O)CCCCCCCCCCCCCCCCC)COP(O)(=O)OCCNC(=O)O{-}CC{+n}OCCN.N
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H331Toxic if inhaled
H336May cause drowsiness or dizziness
H351Suspected of causing cancer
H372Causes damage to organs through prolonged or repeated exposure
H412Harmful to aquatic life with long lasting effects
- Precautionary statements
-
P201Obtain special instructions before use.
P273Avoid release to the environment.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P308+P313IF exposed or concerned: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- D6011
- Product name
- DSPE-PEG(2000)-Amine Ammonium Salt
- Packaging
- 10MG
- Price
- $181
- Updated
- 2025/07/31
- Product number
- 26000
- Product name
- DSPE-PEG(2000)-amine
- Packaging
- 10mg
- Price
- $72
- Updated
- 2021/12/16
- Product number
- 26000
- Product name
- DSPE-PEG(2000)-amine
- Packaging
- 100mg
- Price
- $396
- Updated
- 2021/12/16
- Product number
- 26000
- Product name
- DSPE-PEG(2000)-amine
- Packaging
- 50mg
- Price
- $234
- Updated
- 2021/12/16
- Product number
- FD157101
- Product name
- 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol) 2000] (ammonium salt)
- Packaging
- 10mg
- Price
- $250
- Updated
- 2021/12/16
DSPE-PEG-NH2 Chemical Properties,Usage,Production
Description
DSPE-PEG-Amine, MW 2,000 is a PEG polymer containing DSPE and amine end groups. The DSPE-PEGs have been FDA approved for medical applications. The hydrophobic properties of the DSPE allow for the encapsulation and congregation of other hydrophobic drugs. The hydrophilic PEG increases the water solubility of the overall compound allowing for the delivery of the drug. The amine group can react with activated NHS ester to form a stable amide bond.
Uses
DSPE-PEG-Amine, MW 1000 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG-Amine, MW 1000 (ammonium) can be converted to an aromatic aldehyde, which reacts with an acetone-protected aromatic hydrazine on the surface of the bovine carbonic anhydrase (BCA) molecule. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.
References
[1] Nagata H, et al. Preparation and Catalytic Properties of Carbonic Anhydrase Conjugated to Liposomes through a Bis-Aryl Hydrazone Bond. ACS Omega. 2023 May 16;8(21):18637-18652. DOI:10.1021/acsomega.3c00551
DSPE-PEG-NH2 Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from DSPE-PEG-NH2 manufacturers
- Product
- DSPE-PEG-NH2 474922-26-4
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2025-03-01