4-chloro-N-ethyl-5-(trifluoroMethyl)pyriMidin-2-aMine

Product Name: 4-chloro-N-ethyl-5-(trifluoroMethyl)pyriMidin-2-aMine
CAS No.: 1374829-47-6
Chemical Name: 4-chloro-N-ethyl-5-(trifluoroMethyl)pyriMidin-2-aMine
Synonyms: 2-chloro-N-ethyl-5-(trifluoromethyl)pyrimidin-4-amine;2-chloro-N-ethyl-5-(trifluoromethyl)-4-Pyrimidinamine;4-chloro-N-ethyl-5-(trifluoroMethyl)pyriMidin-2-aMine;2-chloro-4-(ethylamino)-5-(trifluoromethyl)pyrimidine;(2-Chloro-5-trifluoromethyl-pyrimidin-4-yl)-ethyl-amine;4-Pyrimidinamine, 2-chloro-N-ethyl-5-(trifluoromethyl)-
CBNumber: CB22721116
Molecular Formula: C7H7ClF3N3
Formula Weight: 225.6
MOL File: 1374829-47-6.mol

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4-chloro-N-ethyl-5-(trifluoroMethyl)pyriMidin-2-aMine Property

Boiling point:: 319.1±42.0 °C(Predicted)
Density: 1.434±0.06 g/cm3(Predicted)
pka: 0.63±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Crysdot

Product number: CD11269704
Product name: 4-Chloro-N-ethyl-5-(trifluoromethyl)pyrimidin-2-amine
Purity: 95+%
Packaging: 250mg
Price: $262
Updated: 2021/12/16

Chemenu

Product number: CM166180
Product name: 4-Chloro-N-ethyl-5-(trifluoromethyl)pyrimidin-2-amine
Purity: 95%
Packaging: 1g
Price: $611
Updated: 2021/12/16

Crysdot

Product number: CD11269704
Product name: 4-Chloro-N-ethyl-5-(trifluoromethyl)pyrimidin-2-amine
Purity: 95+%
Packaging: 1g
Price: $654
Updated: 2021/12/16

Chemenu

Product number: CM166180
Product name: 4-Chloro-N-ethyl-5-(trifluoromethyl)pyrimidin-2-amine
Purity: 95%
Packaging: 5g
Price: $1834
Updated: 2021/12/16

Crysdot

Product number: CD11269704
Product name: 4-Chloro-N-ethyl-5-(trifluoromethyl)pyrimidin-2-amine
Purity: 95+%
Packaging: 5g
Price: $1961
Updated: 2021/12/16

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4-chloro-N-ethyl-5-(trifluoroMethyl)pyriMidin-2-aMine Chemical Properties,Usage,Production

Synthesis

A solution of 2,4-dichloro-5-(trifluoromethyl)pyrimidine (70 g, 322.61 mmol) in THF (1.4 L) was treated with a solution of ethanolamine (32 g, 709.74 mmol, 46.37 mL) in THF (100 mL) at 0°C, dropwise under N2, over 1 hour. Once the addition was complete, the mixture was stirred at 25°C for 1 hour. The mixture was then filtered and concentrated under reduced pressure to obtain a residue. The residue was subsequently triturated with DCM (200 mL) and filtered. The filtrate was recrystallized with a mixture of n-heptane (600 mL) and MTBE (400 mL). The resulting phase was syrup-like in consistency, and the liquid phase was discarded. The syrup residue was further purified by silica gel column chromatography (PE: EtOAc=20:1) to yield 4-chloro-N-ethyl-5-(trifluoromethyl) pyrimidine-2-amine as a white solid.

4-chloro-N-ethyl-5-(trifluoroMethyl)pyriMidin-2-aMine Preparation Products And Raw materials

Raw materials

Preparation Products

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4-chloro-N-ethyl-5-(trifluoroMethyl)pyriMidin-2-aMine Suppliers

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1374829-47-6, 4-chloro-N-ethyl-5-(trifluoroMethyl)pyriMidin-2-aMineRelated Search:

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4-chloro-N-ethyl-5-(trifluoroMethyl)pyriMidin-2-aMine

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1374829-47-6