ChemicalBook > CAS DataBase List > CZC-54252

CZC-54252

Product Name
CZC-54252
CAS No.
1191911-27-9
Chemical Name
CZC-54252
Synonyms
CS-1730;CZC-54252;CZC-54252, >98%;CZC 54252;CZC54252;CZC 54252 hydrochloride;N-(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)pyrimidin-4-ylamino)phenyl)methanesulfonamide;LRRK2,LRRK2-G2019S,inhibit,neuronal,CZC-54252,injury,neuroprotective,Leucine-rich repeat kinase 2,Inhibitor;N-{2-[(5-chloro-2-{[2-methoxy-4-(morpholin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}methanesulfonamide;Methanesulfonamide, N-[2-[[5-chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]-;N-[2-[[5-Chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]methanesulfonamide hydrochloride
CBNumber
CB22738769
Molecular Formula
C22H25ClN6O4S
Formula Weight
504.99
MOL File
1191911-27-9.mol
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CZC-54252 Property

Boiling point:
718.1±70.0 °C(Predicted)
Density 
1.452±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 
DMF: 20 mg/mL; DMF:PBS(pH 7.2)(1:1): 0.5 mg/mL; DMSO: 10 mg/mL
form 
Powder
pka
8.50±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
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N-Bromosuccinimide Price

Cayman Chemical
Product number
17998
Product name
CZC 54252
Purity
≥98%
Packaging
1mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
17998
Product name
CZC 54252
Purity
≥98%
Packaging
5mg
Price
$130
Updated
2024/03/01
Cayman Chemical
Product number
17998
Product name
CZC 54252
Purity
≥98%
Packaging
10mg
Price
$235
Updated
2024/03/01
Cayman Chemical
Product number
17998
Product name
CZC 54252
Purity
≥98%
Packaging
25mg
Price
$533
Updated
2024/03/01
Tocris
Product number
4534
Product name
CZC54252hydrochloride
Purity
≥98%(HPLC)
Packaging
50
Price
$906
Updated
2021/12/16
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CZC-54252 Chemical Properties,Usage,Production

Uses

CZC 54252 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2). LRRK2 mutations are associated with familial Parkinson''s disease and a potential therapeutic target.

Definition

ChEBI: CZC-25146 is a member of the class of aminopyrimidines that is 2,6-diamino-5-chloropyrimidine in which the amino groups at positions 2 and 6 are respectively carrying 2-methoxy-4-(morpholin-4-yl)phenyl and 2-(methanesulfonylamino)phenyl substituents. It is an inhibitor of the Parkinson's disease kinase LRRK2. It has a role as an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor. It is an aminopyrimidine, a member of morpholines, an aromatic ether, an organochlorine compound, a sulfonamide and a secondary amino compound.

CZC-54252 Preparation Products And Raw materials

Raw materials

Preparation Products

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CZC-54252 Suppliers

Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7553
Advantage
61
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4863
Advantage
58
AdooQ Bioscience CHINA
Tel
025-58849295 18951903616;
Fax
025-68650336
Email
info@adooq.cn
Country
China
ProdList
2989
Advantage
60
Shanghai JiYi Biotechnology Co. Ltd.
Tel
13621943973
Fax
-
Email
sales@shjiyipharmatech.com
Country
China
ProdList
1166
Advantage
55
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4121
Advantage
55
D&C Chemicals
Tel
+86-21-58447131
Fax
+86-21-61642470
Email
1724405207@qq.com
Country
China
ProdList
472
Advantage
55
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8449
Advantage
60
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9926
Advantage
65
ShangHai Siyan Biological Technology Co., Ltd.
Tel
021-50908862,442785678,326799392 18721037013
Fax
021-50908862
Email
siyansales@126.com
Country
China
ProdList
9638
Advantage
58
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9709
Advantage
58
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View Lastest Price from CZC-54252 manufacturers

Career Henan Chemica Co
Product
CZC-54252 1191911-27-9
Price
US $1.00/KG
Min. Order
1KG
Purity
MIn98%HPLC/LC
Supply Ability
100KGS
Release date
2020-10-29

1191911-27-9, CZC-54252Related Search:


  • N-(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)pyrimidin-4-ylamino)phenyl)methanesulfonamide
  • CZC 54252 hydrochloride
  • CZC-54252
  • CS-1730
  • N-[2-[[5-Chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]methanesulfonamide hydrochloride
  • CZC 54252;CZC54252
  • CZC-54252, >98%
  • Methanesulfonamide, N-[2-[[5-chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]-
  • N-{2-[(5-chloro-2-{[2-methoxy-4-(morpholin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}methanesulfonamide
  • LRRK2,LRRK2-G2019S,inhibit,neuronal,CZC-54252,injury,neuroprotective,Leucine-rich repeat kinase 2,Inhibitor
  • 1191911-27-9
  • C22H25ClN6O4S
  • C22H25ClN6O4SHCl
  • Inhibitors