ChemicalBook > CAS DataBase List > H-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-OH

H-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-OH

Product Name
H-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-OH
CAS No.
144189-71-9
Chemical Name
H-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-OH
Synonyms
Aβ22-35;EDVGSNKGAIIGLM;β-Amyloid 22-35;BETA-AMYLOID (22-35);H-EDVLGSNKGAIIGLM-OH;Bate-Amyloid (22-35);Amyloid Peptide (22-35);AMyloid b-Protein (22-35);Amyloid β-Protein (22-35);Amyloid β-Protein (22-35)
CBNumber
CB2279677
Molecular Formula
C59H102N16O21S
Formula Weight
1403.6
MOL File
144189-71-9.mol
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H-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-OH Property

Boiling point:
1805.7±65.0 °C(Predicted)
Density 
1.289±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
Soluble in DMSO
pka
3.24±0.10(Predicted)
form 
Solid
Sequence
H-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-OH
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A5080
Product name
Amyloid β-Protein Fragment 22-35
Purity
≥95% (HPLC)
Packaging
1mg
Price
$363
Updated
2025/07/31
ChemScene
Product number
CS-0044411
Product name
β-Amyloid(22-35)
Packaging
1mg
Price
$70
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA108571
Product name
Amyloid beta-Protein (22-35)
Packaging
1mg
Price
$98
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA108571
Product name
Amyloid beta-Protein (22-35)
Packaging
2mg
Price
$171
Updated
2021/12/16
ChemScene
Product number
CS-0044411
Product name
β-Amyloid(22-35)
Packaging
5mg
Price
$280
Updated
2021/12/16
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H-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-OH Chemical Properties,Usage,Production

Uses

β-Amyloid 22-35 (Amyloid β-Protein 22-35), the residues 22-35 fragment ofβ-amyloid protein, has a cytotoxic effect on cultured neurons from the rat hippocampus in serum-free medium. β-Amyloid 22-35 forms aggregates and typical amyloid fibrils resembling those of the β-amyloid protein in neutral buffer solution)[1].

Biological Activity

Has cytotoxic effect on cultured neurons from r at hippocampus in serum free medium. Also forms aggregates and fibrils similar to those of β-amyloid protein in senile plaque cores.

References

[1] Takadera T, et al. Toxic effect of a beta-amyloid peptide (beta 22-35) on the hippocampal neuron and its prevention. Neurosci Lett. 1993 Oct 14;161(1):41-4. DOI:10.1016/0304-3940(93)90135-8
[2] Zhou WW, et al. Decreasing oxidative stress and neuroinflammation with a multifunctional peptide rescues memory deficits in mice with Alzheimer disease. Free Radic Biol Med. 2014;74:50-63. DOI:10.1016/j.freeradbiomed.2014.06.013

H-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from H-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-OH manufacturers

Zibo Hangyu Biotechnology Development Co., Ltd
Product
Bate-Amyloid (22-35) 144189-71-9
Price
US $0.10-0.30/kg
Min. Order
1kg
Purity
>98%
Supply Ability
20 tons
Release date
2024-01-09
Zibo Hangyu Biotechnology Development Co., Ltd
Product
Amyloid Bate-Protein (22-35)/Bate-Amyloid (22-35) 144189-71-9
Price
US $0.10-0.30/kg
Min. Order
1kg
Purity
>98%
Supply Ability
20 tons
Release date
2024-01-10

144189-71-9, H-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-OHRelated Search:


  • EDVGSNKGAIIGLM
  • H-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-OH
  • GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET
  • BETA-AMYLOID (22-35)
  • AMYLOID B-PROTEIN FRAGMENT 22-35
  • amyloid β-protein fragment 22-35
  • AMYLOID BETA-PROTEIN FRAGMENT 22-35
  • AMYLOID BETA-PROTEIN (22-35)
  • Amyloid beta-protein fragment
  • Amyloid β-Protein (22-35)
  • H-EDVLGSNKGAIIGLM-OH
  • AMyloid b-Protein (22-35)
  • L-Methionine, L-α-glutamyl-L-α-aspartyl-L-valylglycyl-L-seryl-L-asparaginyl-L-lysylglycyl-L-alanyl-L-isoleucyl-L-isoleucylglycyl-L-leucyl-
  • β-Amyloid 22-35
  • Amyloid beta-Protein Fragment 22-35 >=95% (HPLC)
  • Amyloid β-Protein (22-35)/β-Amyloid (22-35)
  • Aβ22-35
  • H-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-OH USP/EP/BP
  • Amyloid β-Protein (22-35)
  • Bate-Amyloid (22-35)
  • Amyloid Bate-Protein (22-35)/Bate-Amyloid (22-35)
  • Amyloid Peptide (22-35)
  • Beta-Amyloid (22-35) - 1 mg
  • 144189-71-9
  • C59H102N16O21S
  • Biochemicals and Reagents
  • Amyloid beta Protein Fragments
  • Peptides
  • Neurodegenerative Disease Peptides
  • BioChemical
  • Amino Acids and Peptides
  • peptide
  • Alzheimers and Neurodegenerative Disease Research
  • Amyloid beta Protein Fragments
  • Amyloid β Protein FragmentsNeuropeptides
  • Neurodegenerative Disease Peptides
  • β Amyloid Peptides