ChemicalBook > CAS DataBase List > IRL-2500

IRL-2500

Product Name
IRL-2500
CAS No.
169545-27-1
Chemical Name
IRL-2500
Synonyms
IRL-2500;L-Tryptophan, 3-[1,1'-biphenyl]-4-yl-N-(3,5-dimethylbenzoyl)-N-methyl-D-alanyl-;N-3-[1,1'-BIPHENYL]-4-YL-N-(3,5-DIMETHYLBENZOYL)-N-METHYL-D-ALANYL-L-TRYPTOPHAN;((R)-3-([1,1'-Biphenyl]-4-yl)-2-(N,3,5-trimethylbenzamido)propanoyl)-L-tryptophan;((R)-3-([1,1'-Biphenyl]-4-yl)-2-(N,3,5-trimethylbenzamido)propanoyl)-L-tryptophan
CBNumber
CB2281962
Molecular Formula
C36H35N3O4
Formula Weight
573.68
MOL File
169545-27-1.mol
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IRL-2500 Property

Boiling point:
893.7±65.0 °C(Predicted)
Density 
1.246±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility 
Soluble to 100 mM in 1eq. NaOH
form 
Powder
pka
3.34±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Tocris
Product number
1838
Product name
IRL-2500
Purity
≥99%(HPLC)
Packaging
10
Price
$280
Updated
2021/12/16
TRC
Product number
I749008
Product name
IRL-2500
Packaging
10mg
Price
$255
Updated
2021/12/16
Usbiological
Product number
255524
Product name
IRL-2500
Packaging
10mg
Price
$545
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0008078
Product name
IRL-2500
Purity
95.00%
Packaging
1G
Price
$754.95
Updated
2021/12/16
ChemScene
Product number
CS-0027938
Product name
IRL2500
Purity
>99.0%
Packaging
10mg
Price
$795
Updated
2021/12/16
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IRL-2500 Chemical Properties,Usage,Production

Uses

IRL 2500 is a potent endothelin ETB selective antagonist.

Biological Activity

Potent endothelin receptor antagonist; shows some selectivity for ET B receptors (IC 50 values are 1.3 and 94 nM for ET B and ET A receptors respectively). Inhibits ET B receptor-mediated blood pressure increase and renal vascular resistance in rats in vivo .

storage

Desiccate at RT

IRL-2500 Preparation Products And Raw materials

Raw materials

Preparation Products

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IRL-2500 Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
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3bsc@sina.com
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Shanghai Chaolan Chemical Technology Center
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QQ:65489617 15618227136
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21-5161 9052
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Aikon International Limited
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jnyaoyan@163.com
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Nanjing Meihao Pharmaceutical Technology Co., Ltd.
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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169545-27-1, IRL-2500Related Search:


  • IRL-2500
  • N-3-[1,1'-BIPHENYL]-4-YL-N-(3,5-DIMETHYLBENZOYL)-N-METHYL-D-ALANYL-L-TRYPTOPHAN
  • L-Tryptophan, 3-[1,1'-biphenyl]-4-yl-N-(3,5-dimethylbenzoyl)-N-methyl-D-alanyl-
  • ((R)-3-([1,1'-Biphenyl]-4-yl)-2-(N,3,5-trimethylbenzamido)propanoyl)-L-tryptophan
  • ((R)-3-([1,1'-Biphenyl]-4-yl)-2-(N,3,5-trimethylbenzamido)propanoyl)-L-tryptophan
  • 169545-27-1
  • C36H35N3O4
  • Endothelin receptor