ChemicalBook > CAS DataBase List > IRL-2500

IRL-2500

Product Name
IRL-2500
CAS No.
169545-27-1
Chemical Name
IRL-2500
Synonyms
IRL-2500;L-Tryptophan, 3-[1,1'-biphenyl]-4-yl-N-(3,5-dimethylbenzoyl)-N-methyl-D-alanyl-;N-3-[1,1'-BIPHENYL]-4-YL-N-(3,5-DIMETHYLBENZOYL)-N-METHYL-D-ALANYL-L-TRYPTOPHAN;((R)-3-([1,1'-Biphenyl]-4-yl)-2-(N,3,5-trimethylbenzamido)propanoyl)-L-tryptophan;((R)-3-([1,1'-Biphenyl]-4-yl)-2-(N,3,5-trimethylbenzamido)propanoyl)-L-tryptophan
CBNumber
CB2281962
Molecular Formula
C36H35N3O4
Formula Weight
573.68
MOL File
169545-27-1.mol
More
Less

IRL-2500 Property

Boiling point:
893.7±65.0 °C(Predicted)
Density 
1.246±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility 
Soluble to 100 mM in 1eq. NaOH
form 
Powder
pka
3.34±0.10(Predicted)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Tocris
Product number
1838
Product name
IRL-2500
Purity
≥99%(HPLC)
Packaging
10
Price
$280
Updated
2021/12/16
TRC
Product number
I749008
Product name
IRL-2500
Packaging
10mg
Price
$255
Updated
2021/12/16
Usbiological
Product number
255524
Product name
IRL-2500
Packaging
10mg
Price
$545
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0008078
Product name
IRL-2500
Purity
95.00%
Packaging
1G
Price
$754.95
Updated
2021/12/16
ChemScene
Product number
CS-0027938
Product name
IRL2500
Purity
>99.0%
Packaging
10mg
Price
$795
Updated
2021/12/16
More
Less

IRL-2500 Chemical Properties,Usage,Production

Uses

IRL 2500 is a potent endothelin ETB selective antagonist.

Biological Activity

Potent endothelin receptor antagonist; shows some selectivity for ET B receptors (IC 50 values are 1.3 and 94 nM for ET B and ET A receptors respectively). Inhibits ET B receptor-mediated blood pressure increase and renal vascular resistance in rats in vivo .

storage

Desiccate at RT

IRL-2500 Preparation Products And Raw materials

Raw materials

Preparation Products

169545-27-1, IRL-2500Related Search:


  • IRL-2500
  • N-3-[1,1'-BIPHENYL]-4-YL-N-(3,5-DIMETHYLBENZOYL)-N-METHYL-D-ALANYL-L-TRYPTOPHAN
  • L-Tryptophan, 3-[1,1'-biphenyl]-4-yl-N-(3,5-dimethylbenzoyl)-N-methyl-D-alanyl-
  • ((R)-3-([1,1'-Biphenyl]-4-yl)-2-(N,3,5-trimethylbenzamido)propanoyl)-L-tryptophan
  • ((R)-3-([1,1'-Biphenyl]-4-yl)-2-(N,3,5-trimethylbenzamido)propanoyl)-L-tryptophan
  • 169545-27-1
  • C36H35N3O4
  • Endothelin receptor