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L-4-CHLOROPHENYLALANINE METHYL ESTER HCL

Product Name
L-4-CHLOROPHENYLALANINE METHYL ESTER HCL
CAS No.
63024-26-0
Chemical Name
L-4-CHLOROPHENYLALANINE METHYL ESTER HCL
Synonyms
Methyl 4-chloro-L-phenylalaninate;L-4-CHLOROPHENYLALANINE METHYL ESTER HCL;METHYL 4-CHLORO-L-PHENYLALANINATE HYDROCHLORIDE;P-CHLOROPHENYLALANINE METHYLESTER HYDROCHLORIDE;L-3-(2-Naphthyl)alanine methyl ester hydrochloride;β-(2-naphthyl)-L-alanine methyl ester hydrochloride;METHYL (2S)-2-AMINO-3-(4-CHLOROPHENYL)PROPANOATE HCL;(S)-Methyl 2-amino-3-(naphthalen-2-yl)propanoate HCl;beta-(2-Naphthyl)-L-alanine Methyl Ester Hydrochloride;(S)-Methyl 2-amino-3-(naphthalen-2-yl)propanoate hydrochloride
CBNumber
CB2283461
Molecular Formula
C10H13Cl2NO2
Formula Weight
250.12
MOL File
63024-26-0.mol
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L-4-CHLOROPHENYLALANINE METHYL ESTER HCL Property

storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
Appearance
White to off-white Solid
optical activity
18.6°(C=0.01g/ml ETOH)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
N378053
Product name
L-2-Naphthylalaninemethylesterhydrochloride
Packaging
10mg
Price
$45
Updated
2021/12/16
Chem-Impex
Product number
14304
Product name
L-2-Naphthylalaninemethylesterhydrochloride,≥99%(HPLC)
Purity
≥99%(HPLC)
Packaging
1G
Price
$36.22
Updated
2021/12/16
Chem-Impex
Product number
14304
Product name
L-2-Naphthylalaninemethylesterhydrochloride,≥99%(HPLC)
Purity
≥99%(HPLC)
Packaging
5G
Price
$144.44
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
AAA0017211
Product name
METHYL-(2S)-2-AMINO-3-(4-CHLOROPHENYL)PROPANOATE HYDROCHLORIDE
Purity
95.00%
Packaging
5MG
Price
$495.65
Updated
2021/12/16
Chem-Impex
Product number
14304
Product name
L-2-Naphthylalaninemethylesterhydrochloride,≥99%(HPLC)
Purity
≥99%(HPLC)
Packaging
25G
Price
$518.34
Updated
2021/12/16
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L-4-CHLOROPHENYLALANINE METHYL ESTER HCL Chemical Properties,Usage,Production

Synthesis

176896-73-4

63024-26-0

Step B: Methyl (2S)-2-(tert-butoxycarbonylamino)-3-(naphthalen-2-yl)propionate (5.52 g, 15.85 mmol) and 20 mL of ethyl acetate were added to a 500 mL round-bottom flask fitted with a magnetic stirrer. 80 mL of 2.8 M hydrogen chloride in ethyl acetate solution was slowly added under stirring and the reaction was carried out under nitrogen protection for 2.5 hours. Upon completion of the reaction, the reaction mixture was concentrated to dryness under reduced pressure to give the crude product. The crude product was dissolved in an appropriate amount of ethyl acetate, stirred for 10 minutes and filtered to collect the solid. The resulting solid was dried under vacuum at 40 °C to give (2S)-2-amino-3-(naphthalen-2-yl)propanoic acid methyl ester hydrochloride 3.91 g in 93% yield as a white solid.HPLC-MS analysis: retention time (Rt) = 3.70 min, molecular ion peak (M + 1) = 230, % ELS area = 100%.

References

[1] Patent: US2007/185128, 2007, A1. Location in patent: Page/Page column 27

L-4-CHLOROPHENYLALANINE METHYL ESTER HCL Preparation Products And Raw materials

Raw materials

Preparation Products

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L-4-CHLOROPHENYLALANINE METHYL ESTER HCL Suppliers

Shanghai HC Biotech Co., Ltd
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021-20227858
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+86-21-20227857
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sale@hcbiotech.com.cn
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China
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4009209199
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86-021-52271987
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sales@9dingchem.com
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China
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Tel
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021-50323701
Email
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China
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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
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Career Henan Chemica Co
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63024-26-0, L-4-CHLOROPHENYLALANINE METHYL ESTER HCLRelated Search:


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  • METHYL 4-CHLORO-L-PHENYLALANINATE HYDROCHLORIDE
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  • Methyl 4-chloro-L-phenylalaninate
  • METHYL (2S)-2-AMINO-3-(4-CHLOROPHENYL)PROPANOATE HCL
  • L-3-(2-Naphthyl)alanine methyl ester hydrochloride
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  • β-(2-naphthyl)-L-alanine methyl ester hydrochloride
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  • methyl (S)-2-amino-3-(naphthalen-2-yl)propanoate hydrochloride
  • beta-(2-Naphthyl)-L-alanine Methyl Ester Hydrochloride
  • (S)-Methyl 2-amino-3-(naphthalen-2-yl)propanoate HCl
  • 63024-26-0