L-4-CHLOROPHENYLALANINE METHYL ESTER HCL
- Product Name
- L-4-CHLOROPHENYLALANINE METHYL ESTER HCL
- CAS No.
- 63024-26-0
- Chemical Name
- L-4-CHLOROPHENYLALANINE METHYL ESTER HCL
- Synonyms
- Methyl 4-chloro-L-phenylalaninate;L-4-CHLOROPHENYLALANINE METHYL ESTER HCL;METHYL 4-CHLORO-L-PHENYLALANINATE HYDROCHLORIDE;P-CHLOROPHENYLALANINE METHYLESTER HYDROCHLORIDE;L-3-(2-Naphthyl)alanine methyl ester hydrochloride;β-(2-naphthyl)-L-alanine methyl ester hydrochloride;METHYL (2S)-2-AMINO-3-(4-CHLOROPHENYL)PROPANOATE HCL;(S)-Methyl 2-amino-3-(naphthalen-2-yl)propanoate HCl;beta-(2-Naphthyl)-L-alanine Methyl Ester Hydrochloride;(S)-Methyl 2-amino-3-(naphthalen-2-yl)propanoate hydrochloride
- CBNumber
- CB2283461
- Molecular Formula
- C10H13Cl2NO2
- Formula Weight
- 250.12
- MOL File
- 63024-26-0.mol
L-4-CHLOROPHENYLALANINE METHYL ESTER HCL Property
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- Appearance
- White to off-white Solid
- optical activity
- 18.6°(C=0.01g/ml ETOH)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- N378053
- Product name
- L-2-Naphthylalaninemethylesterhydrochloride
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 14304
- Product name
- L-2-Naphthylalaninemethylesterhydrochloride,≥99%(HPLC)
- Purity
- ≥99%(HPLC)
- Packaging
- 1G
- Price
- $36.22
- Updated
- 2021/12/16
- Product number
- 14304
- Product name
- L-2-Naphthylalaninemethylesterhydrochloride,≥99%(HPLC)
- Purity
- ≥99%(HPLC)
- Packaging
- 5G
- Price
- $144.44
- Updated
- 2021/12/16
- Product number
- AAA0017211
- Product name
- METHYL-(2S)-2-AMINO-3-(4-CHLOROPHENYL)PROPANOATE HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495.65
- Updated
- 2021/12/16
- Product number
- 14304
- Product name
- L-2-Naphthylalaninemethylesterhydrochloride,≥99%(HPLC)
- Purity
- ≥99%(HPLC)
- Packaging
- 25G
- Price
- $518.34
- Updated
- 2021/12/16
L-4-CHLOROPHENYLALANINE METHYL ESTER HCL Chemical Properties,Usage,Production
Synthesis
176896-73-4
63024-26-0
Step B: Methyl (2S)-2-(tert-butoxycarbonylamino)-3-(naphthalen-2-yl)propionate (5.52 g, 15.85 mmol) and 20 mL of ethyl acetate were added to a 500 mL round-bottom flask fitted with a magnetic stirrer. 80 mL of 2.8 M hydrogen chloride in ethyl acetate solution was slowly added under stirring and the reaction was carried out under nitrogen protection for 2.5 hours. Upon completion of the reaction, the reaction mixture was concentrated to dryness under reduced pressure to give the crude product. The crude product was dissolved in an appropriate amount of ethyl acetate, stirred for 10 minutes and filtered to collect the solid. The resulting solid was dried under vacuum at 40 °C to give (2S)-2-amino-3-(naphthalen-2-yl)propanoic acid methyl ester hydrochloride 3.91 g in 93% yield as a white solid.HPLC-MS analysis: retention time (Rt) = 3.70 min, molecular ion peak (M + 1) = 230, % ELS area = 100%.
References
[1] Patent: US2007/185128, 2007, A1. Location in patent: Page/Page column 27
L-4-CHLOROPHENYLALANINE METHYL ESTER HCL Preparation Products And Raw materials
Raw materials
Preparation Products
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