ChemicalBook > CAS DataBase List > 5-FORMYL-2-METHOXY-4-PICOLINE

5-FORMYL-2-METHOXY-4-PICOLINE

Product Name: 5-FORMYL-2-METHOXY-4-PICOLINE
CAS No.: 123506-66-1
Chemical Name: 5-FORMYL-2-METHOXY-4-PICOLINE
Synonyms: CML-015;5-FORMYL-2-METHOXY-4-PICOLINE;2-Fluoro-37-(methylthio)pyridine;6-methoxy-4-methylnicotinaldehyde;6-Methoxy-4-methyl-3-pyridinecarboxaldehyde;3-Pyridinecarboxaldehyde, 6-methoxy-4-methyl-;3-Pyridinecarboxaldehyde, 6-methoxy-4-methyl- (9CI)
CBNumber: CB2284615
Molecular Formula: C8H9NO2
Formula Weight: 151.16
MOL File: 123506-66-1.mol

Less

5-FORMYL-2-METHOXY-4-PICOLINE Property

Melting point:: 91-92 °C(Solv: hexane (110-54-3))
Boiling point:: 274.2±35.0 °C(Predicted)
Density: 1.123±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 2.25±0.18(Predicted)
Appearance: White to off-white Solid

Less

Hazard and Precautionary Statements (GHS)

Less

N-Bromosuccinimide Price

AK Scientific

Product number: Y3924
Product name: 5-Formyl-2-methoxy-4-picoline
Packaging: 250mg
Price: $118
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0166308
Product name: 5-FORMYL-2-METHOXY-4-PICOLINE
Purity: 98.00%
Packaging: 5MG
Price: $501.08
Updated: 2021/12/16

Crysdot

Product number: CD11319793
Product name: 6-Methoxy-4-methylnicotinaldehyde
Purity: 95%
Packaging: 5g
Price: $594
Updated: 2021/12/16

Abosyn

Product number: 61-2808
Product name: 6-Methoxy-4-methylnicotinaldehyde
Purity: 95%-98%
Packaging: 0.25g
Price: $810
Updated: 2021/12/16

Chemenu

Product number: CM125922
Product name: 6-methoxy-4-methylnicotinaldehyde
Purity: 95%
Packaging: 5g
Price: $832
Updated: 2021/12/16

Less

5-FORMYL-2-METHOXY-4-PICOLINE Chemical Properties,Usage,Production

Synthesis

68-12-2

164513-39-7

123506-66-1

General procedure for the synthesis of 5-formyl-2-methoxy-4-methyl-4-methylpyridine from 2-methoxy-4-methyl-5-bromopyridine and N,N-dimethylformamide: 5-bromo-2-methoxy-4-methylpyridine (2.6 g, 13 mmol) was dissolved in anhydrous THF (40 mL) and cooled to -70 °C under argon protection. A hexane solution of 1.6 M n-butyllithium (8.1 mL, 14 mmol) was slowly added over 10 min with stirring. The reaction temperature was maintained at -70 °C and stirring was continued for 30 min. Subsequently, anhydrous DMF (1.2 mL, 15 mmol) was added in batches, keeping the temperature constant. After addition, stirring was continued at -70 °C for 30 min, then brought to room temperature and stirred overnight. Upon completion of the reaction, the reaction was quenched with 1 M hydrochloric acid (40 mL) and subsequently extracted three times with tert-butyl methyl ether (TBME). The organic phases were combined, washed with brine, dried over anhydrous sodium sulfate, filtered and concentrated. Purification by column chromatography using tert-butyl methyl ether-light petroleum ether (1:1) as eluent afforded 1.8 g (91% yield) of 5-formyl-2-methoxy-4-methylpyridine as a light yellow solid.LC-MS m/z 152 (M + 1); 1H NMR (CDCl3) δ 10.1 (s, 1H), 8.55 (s, 1H), 6.61 ( s, 1H), 4.05 (s, 3H), 2.60 (s, 3H) ppm.

References

[1] Patent: WO2006/65215, 2006, A1. Location in patent: Page/Page column 19; 35
[2] Synthetic Communications, 2009, vol. 39, # 17, p. 3060 - 3068
[3] Patent: WO2015/158427, 2015, A1. Location in patent: Page/Page column 84; 85

5-FORMYL-2-METHOXY-4-PICOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

Less

5-FORMYL-2-METHOXY-4-PICOLINE Suppliers

China 63 Europe 1 India 1 United States 6 Global 71

Tetranov Biopharm

Tel: 13526569071
Email: sales@leadmedpharm.com
Country: China
ProdList: 7892
Advantage: 64

SynAsst Chemical.

Tel: 021-60343070
Fax: 021-35122006
Country: China
ProdList: 12740
Advantage: 55

Anichem Inc.

Tel: 0512-69369885
Fax: 0512-69369880
Email: sales@anichem.com.cn
Country: China
ProdList: 495
Advantage: 55

Shanghai Hong-chuang Pharma Tech Co., Ltd.

Tel: 18151128828
Fax: -
Email: hc-sales@foxmail.com
Country: China
ProdList: 2647
Advantage: 55

Porse Fine Chemical Co.,LTD

Tel: 20-66003216 18666003216
Fax: +86-20-28069063
Email: info@porsefinechemical.com
Country: China
ProdList: 1941
Advantage: 62

Hangzhou Milestone Pharmtech Co., Ltd.

Tel: 0571-82896630 18969958410
Email: sales_hz@milestonepharmtech.com
Country: China
ProdList: 4895
Advantage: 55

ShangHai Angti Biotechnology Co., Ltd.

Tel: 13764913901
Fax: -
Email: info@angtibio.com
Country: China
ProdList: 4984
Advantage: 55

Hubei Chuangliankangcheng Pharmaceutical Co., Ltd.

Tel: 027-65388397 18164111589
Fax: 027-65388397
Email: 3321478047@qq.com
Country: China
ProdList: 2007
Advantage: 55

ShangHai Siyan Biological Technology Co., Ltd.

Tel: 021-50908862，442785678，326799392 18721037013
Fax: 021-50908862
Email: siyansales@126.com
Country: China
ProdList: 9627
Advantage: 58

Zhengzhou AiXi Technology Co., Ltd.

Tel: 0371-56787280 13137706083
Fax: -
Email: m18539565376@163.com
Country: China
ProdList: 970
Advantage: 55

Shanghai QianYan Bio-technology Co., Ltd

Tel: 02781293128
Email: orders@biochemsafebuy.com
Country: China
ProdList: 9923
Advantage: 55

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Nanjing YakeLun Pharmaceutical Co., Ltd.

Tel: 025-66096098 3165145969
Fax: QQ3165145969
Email: sales@accoronpharm.com
Country: China
ProdList: 3924
Advantage: 55

Shanghai Kangman Biological Technology Co., Ltd.

Tel: 18800375331
Fax: 021-50908862
Email: kangmansales@163.com
Country: China
ProdList: 7570
Advantage: 55

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: 02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 15083
Advantage: 58

SHANGHAI FDC-CHEMICAL CO.,LTD

Tel: 021-61469567 13482353728
Fax: 021-61161605
Email: sales@fdc-chemical.com
Country: China
ProdList: 9722
Advantage: 58

Hebei Huaxing Chemical Co., Ltd

Tel: 0319-6931777 13930968617
Fax: +86-319-6931577
Email: 630669494@qq.com
Country: China
ProdList: 1021
Advantage: 58

Cool Pharm, Ltd

Tel: 021-58581007 18019463053
Fax: 021-50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12878
Advantage: 58

ANHUI WITOP BIOTECH CO., LTD

Tel: +8615255079626
Email: eric@witopchemical.com
Country: China
ProdList: 23541
Advantage: 58

Zhejiang J&C Biological Technology Co.,Limited

Tel: +1-2135480471
Email: sales@sarms4muscle.com
Country: China
ProdList: 10473
Advantage: 58

Hubei Jusheng Technology Co.,Ltd.

Tel: 18871490254
Fax: 027-59599243
Email: linda@hubeijusheng.com
Country: CHINA
ProdList: 28172
Advantage: 58

LEADMEDPHARM CO.,LTD

Tel: 13674959855 13674959855
Email: sales@synthontech.com
Country: China
ProdList: 3035
Advantage: 58

Changzhou Yinghao Technology Development Co., Ltd

Tel: 15151934985
Email: sales@yingsapharm.com
Country: China
ProdList: 5181
Advantage: 58

Shanghai Kaiwei Chemical Technology Co., Ltd.

Tel: 021-58461859 15821823057
Email: service@aiviche.com
Country: China
ProdList: 49312
Advantage: 58

career henan chemical co

Tel: +86-0371-86658258 +8613203830695
Fax: 0086-371-86658258
Email: factory@coreychem.com
Country: China
ProdList: 29798
Advantage: 58

Shaanxi Dideu Medichem Co. Ltd

Tel: +86-29-81148696 +86-17392712697
Email: 1022@dideu.com
Country: China
ProdList: 3995
Advantage: 58

Huzhou fuhe Rui biological medicine co., ltd

Tel: 13626726938
Country: China
ProdList: 791
Advantage: 58

Guangzhou Yuheng Pharmaceutical Technology Co., Ltd

Tel: +8613580539051
Email: joe@yuhengpharm.com
Country: CHINA
ProdList: 21142
Advantage: 58

Jiaxing Hengrui Biotechnology Co. LTD

Tel: 0573-0573-82672231 13757365595
Fax: QQ：715584339
Email: regen_chemical1@163.com
Country: China
ProdList: 4839
Advantage: 58

Zhengzhou Convergence Chemical Co. LTD

Tel: 0371-0371-53736046 13393710386
Fax: QQ:2853979814
Email: 2853979814@qq.com
Country: China
ProdList: 9948
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44894
Advantage: 58

Weihai Huaixin Biotechnology Co., Ltd

Tel: 15662379806
Email: 845423637@qq.com
Country: China
ProdList: 1656
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 40000
Advantage: 58

Hefei Ruiluo New Material Technology Co., Ltd.

Tel: 19567218739
Email: 1759672789@qq.com
Country: China
ProdList: 868
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39653
Advantage: 58

Tianjin Xinghan Biotechnology Co., Ltd

Tel: 13230698506 18698089028
Email: 1725517238@qq.com
Country: China
ProdList: 5009
Advantage: 58

Qingzhou dafeng import and export Co. LTD

Tel: 16773308882
Email: 927608786@qq.com
Country: China
ProdList: 3051
Advantage: 58

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 13901585132
Email: 2261760024@qq.com
Country: China
ProdList: 4900
Advantage: 58

Beijing InnoChem Science & Technology Co., Ltd.

Tel: 15652467323
Email: sales@inno-chem.com.cn
Country: China
ProdList: 8293
Advantage: 58

TianJin JinSheng Biomedical Co., Ltd

Tel: 13820634634 18622687818
Email: 405423999@qq.com
Country: China
ProdList: 3298
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 17801761073
Email: Gsiyu@solarbio.com
Country: China
ProdList: 50464
Advantage: 58

PharmaBlock Sciences (Nanjing), Inc.

Tel: 4000255188
Email: marketing@pharmablock.com
Country: China
ProdList: 9126
Advantage: 58

Zhuhai Aobokai Biomedical Technology Co., Ltd.

Tel: 400-0628126 18736790110;
Email: sales-team@aobchem.com.cn
Country: China
ProdList: 50000
Advantage: 58

https://hanhongsci.com/

Tel: 021-54306202 18917919676
Email: info@hanhongsci.com
Country: China
ProdList: 29995
Advantage: 58

Huzhou Chengbo Biotechnology Co., Ltd

Tel: 13626726938
Country: China
ProdList: 3879
Advantage: 58

Nanjing Bic Biotechnology Co., Ltd

Tel: 025-58906079 17352406906
Email: sales@bicbiotech.com
Country: China
ProdList: 5996
Advantage: 58

Liaocheng Lebote Biopharmaceutical Technology Co., Ltd

Tel: 0635-893290 18663513896;
Email: 28698871@qq.com
Country: China
ProdList: 8022
Advantage: 58

Yantai Shengkailun Chemical Technology Co., Ltd.

Tel: 13356901049
Email: mark@sklnchem.cn
Country: China
ProdList: 9995
Advantage: 58

Shaoyuan Technology (Shanghai) Co., Ltd.

Tel: 021-50795510 4000665055
Email: sy-c5@accelachem.com
Country: China
ProdList: 10000
Advantage: 58

Huzhou Qingliu Silicate Biotechnology Co., Ltd

Tel: 13626726938
Email: 15952452933@163.cn
Country: China
ProdList: 4109
Advantage: 58

Less

View Lastest Price from 5-FORMYL-2-METHOXY-4-PICOLINE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 5-Formyl-2-methoxy-4-picoline 123506-66-1
Price: US $0.10/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 1000 tons
Release date: 2019-12-27

Career Henan Chemical Co

Product: 5-FORMYL-2-METHOXY-4-PICOLINE 123506-66-1
Price: US $9.80/KG
Min. Order: 1g
Purity: ≥99%
Supply Ability: 100kg
Release date: 2020-01-12

123506-66-1, 5-FORMYL-2-METHOXY-4-PICOLINERelated Search:

3-Pyridinecarboxaldehyde 2-METHOXY-4-(TRIFLUOROMETHYL)PYRIDINE-5-CARBOXAMIDE 6-[(QUINOLIN-8-YL)OXY]-4-(TRIFLUOROMETHYL)PYRIDINE-3-CARBOXYLIC ACID, METHYL ESTER 5-FORMYL-2-METHOXY-4-PICOLINE 2-CHLORO-6-METHOXY-4-(TRIFLUOROMETHYL)NICOTINAMIDE Nicotinic acid, 6-(3-diethylamino-2-hydroxypropoxy)-2,4-dimethyl-, eth yl ester

5-FORMYL-2-METHOXY-4-PICOLINE

3-Pyridinecarboxaldehyde, 6-methoxy-4-methyl- (9CI)

6-methoxy-4-methylnicotinaldehyde

6-Methoxy-4-methyl-3-pyridinecarboxaldehyde

CML-015

3-Pyridinecarboxaldehyde, 6-methoxy-4-methyl-

2-Fluoro-37-(methylthio)pyridine

123506-66-1

ALDEHYDE

Pyridine