DODECYLPHOSPHORYLCHOLINE-D38
- Product Name
- DODECYLPHOSPHORYLCHOLINE-D38
- CAS No.
- 130890-78-7
- Chemical Name
- DODECYLPHOSPHORYLCHOLINE-D38
- Synonyms
- 12:0 D38 CP;MAPCHO-12-D38;MAPCHO(R)-12-d38;DODECYLPHOSPHOCHOLINE-D38;MAPCHO?-12-d38;D38-Dodecylphosphocholine;n-Dodecylphosphocholine-d38;Dodecylphosphorylcholine-d??;DODECYLPHOSPHORYLCHOLINE-D38;Dodecylphosphocholine (D??, 98%)
- CBNumber
- CB2284842
- Molecular Formula
- C17D38NO4P
- Formula Weight
- 389.7
- MOL File
- 130890-78-7.mol
DODECYLPHOSPHORYLCHOLINE-D38 Property
- Melting point:
- 247-249 °C(lit.)
- storage temp.
- -20°C
- solubility
- DMF: 16 mg/ml; DMSO: 16 mg/ml; Ethanol: 15 mg/ml; PBS (pH 7.2): 25 mg/ml
- form
- A crystalline solid
- color
- White to off-white
- InChIKey
- QBHFVMDLPTZDOI-DHIOKLJKSA-N
- CAS Number Unlabeled
- 29557-51-5
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- 485616
- Product name
- Dodecylphosphorylcholine-d38
- Purity
- 98 atom % D
- Packaging
- 500mg
- Price
- $1250
- Updated
- 2025/07/31
- Product number
- 25996
- Product name
- Dodecylphosphocholine-d38
- Purity
- ≥99% deuterated forms (d1-d38)
- Packaging
- 25mg
- Price
- $90
- Updated
- 2024/03/01
- Product number
- 25996
- Product name
- Dodecylphosphocholine-d38
- Purity
- ≥99% deuterated forms (d1-d38)
- Packaging
- 50mg
- Price
- $172
- Updated
- 2024/03/01
- Product number
- 25996
- Product name
- Dodecylphosphocholine-d38
- Purity
- ≥99% deuterated forms (d1-d38)
- Packaging
- 100mg
- Price
- $306
- Updated
- 2024/03/01
- Product number
- 25996
- Product name
- Dodecylphosphocholine-d38
- Purity
- ≥99% deuterated forms (d1-d38)
- Packaging
- 250mg
- Price
- $494
- Updated
- 2024/03/01
DODECYLPHOSPHORYLCHOLINE-D38 Chemical Properties,Usage,Production
Description
Dodecylphosphocholine-d38 is intended for use as an internal standard for the quantification of dodecylphosphocholine by GC- or LC-MS. Dodecylphosphocholine is a detergent that is commonly used for membrane protein structure determination using NMR. It has also been used to generate membrane mimetic micelles and to characterize pore formation by the influenza M2 transmembrane domain within a synthetic membrane. Dodecylphosphocholine micelles induce amyloid fibril formation by the prion protein (PrP) β-strand (PrP (110-136)). Dodecylphosphocholine has a critical micelle concentration (CMC) of approximately 1.5 mM.
Uses
MAPCHO?-12-d38 has been used in the preparation of drug complexes used as a sample during nuclear magnetic resonance (NMR) spectroscopy.
References
[1] VILIUS KURAUSKAS. How Detergent Impacts Membrane Proteins: Atomic-Level Views of Mitochondrial Carriers in Dodecylphosphocholine.[J]. The Journal of Physical Chemistry Letters, 2018, 9 5: 933-938. DOI: 10.1021/acs.jpclett.8b00269
[2] SARAH D. CADY. Specific Binding of Adamantane Drugs and Direction of Their Polar Amines in the Pore of the Influenza M2 Transmembrane Domain in Lipid Bilayers and Dodecylphosphocholine Micelles Determined by NMR Spectroscopy[J]. Journal of the American Chemical Society, 2011, 133 12: 4274-4284. DOI: 10.1021/ja102581n
[3] S. SAUVé Y A. Dodecylphosphocholine Micelles Induce Amyloid Formation of the PrP(110-136) Peptide via an α-Helical Metastable Conformation[J]. PLoS ONE, 2016, 11 1. DOI: 10.1371/journal.pone.0168021
DODECYLPHOSPHORYLCHOLINE-D38 Preparation Products And Raw materials
Raw materials
Preparation Products
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