ChemicalBook > CAS DataBase List > 6-HYDROXYDOPAMINE HYDROBROMIDE
6-HYDROXYDOPAMINE HYDROBROMIDE
- Product Name
- 6-HYDROXYDOPAMINE HYDROBROMIDE
- CAS No.
- 636-00-0
- Chemical Name
- 6-HYDROXYDOPAMINE HYDROBROMIDE
- Synonyms
- Oxidopamine HBr;6-HYDROXYDOPAMINE HBR;6-OHDA (hydrobromide);6-Hydroxydopamine hydrbromide;2,4,5-Trihydroxyphenethylamine;6-HYDROXYDOPAMINE HYDROBROMIDE;KEMPTIDE, SYNTHETIC, >97% PURITY;Oxidopamine (6-OHDA) hydrobromide;2,5-DIHYDROXYTYRAMINE HYDROBROMIDE;6-HYDROXYDOPAMINE HYDROBROMIDE 99%
- CBNumber
- CB2288961
- Molecular Formula
- C8H12BrNO3
- Formula Weight
- 250.09
- MOL File
- 636-00-0.mol
More
Less
6-HYDROXYDOPAMINE HYDROBROMIDE Property
- Melting point:
- 216-220 °C(lit.)
- storage temp.
- -20°C
- solubility
- DMSO (Slightly), Methanol (Slightly), Water (Slightly)
- form
- solid
- color
- tan to brown
- BRN
- 3713280
- Stability:
- Hygroscopic, Light Sensitive
- InChIKey
- MLACDGUOKDOLGC-UHFFFAOYSA-N
- CAS DataBase Reference
- 636-00-0(CAS DataBase Reference)
More
Less
More
Less
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
More
Less
N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 162957
- Product name
- 6-Hydroxydopamine hydrobromide
- Purity
- 95%
- Packaging
- 1g
- Price
- $479
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 162957
- Product name
- 6-Hydroxydopamine hydrobromide
- Purity
- 95%
- Packaging
- 5g
- Price
- $1146
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 25330
- Product name
- 6-OHDA (hydrobromide)
- Purity
- ≥95%
- Packaging
- 50mg
- Price
- $37
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 162957
- Product name
- 6-Hydroxydopamine hydrobromide
- Purity
- 95%
- Packaging
- 50mg
- Price
- $41.5
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 162957
- Product name
- 6-Hydroxydopamine hydrobromide
- Purity
- 95%
- Packaging
- 250mg
- Price
- $147
- Updated
- 2024/03/01
More
Less
6-HYDROXYDOPAMINE HYDROBROMIDE Chemical Properties,Usage,Production
Description
6-OHDA is a catecholaminergic neurotoxin that has been used to induce dopaminergic lesions and parkinsonian symptoms as a model of Parkinson''s disease in rodents. It induces locomotor impairment in mice and loss of tyrosine hydroxylase-reactive neurons in mouse brain when administered into the substantia nigra, medial forebrain bundle (MFB), or striatum at doses of 9, 6, and 18 μg, respectively. Intracisternal administration of 6-OHDA (200 μg) decreases dopamine and norepinephrine levels in rat brain. It induces apoptosis in primary rat cortical cells and PC12 rat adrenal cells when used at a concentration of 50 μM. 6-OHDA (75 μM) activates caspase-3, -8, and -9 in a time-dependent manner and increases the level of intracellular reactive oxygen species (ROS) in PC12 cells and induces apoptosis in rat substantia nigra when stereotaxically injected into the right MFB.
Chemical Properties
beige to brown crystalline powder
Uses
6-Hydroxydopamine is a selective catecholaminergic neurotoxin. Studies show that 6-Hydroxydopamine can be used to create an animal model of Parkinson''s disease as it causes almost complete destruction of nigral dopaminergic neurons and their striatal terminals when injected into the substantia nigra of rats. 6-Hydroxydopamine induces apoptosis in PC12 cells.
General Description
Solutions should be freshly prepared and protected from exposure to light.
Biochem/physiol Actions
Neurotoxin that destroys catecholaminergic terminals.
storage
-20°C
6-HYDROXYDOPAMINE HYDROBROMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
6-HYDROXYDOPAMINE HYDROBROMIDE Suppliers
- Tel
- 1351-2466848 13512466848
- Fax
- QQ:94204388
- hbdypharm@163.com
- Country
- China
- ProdList
- 216
- Advantage
- 58
- Tel
- 010-82848833 400-666-7788
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 94657
- Advantage
- 76
- Tel
- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
- 3bsc@sina.com
- Country
- China
- ProdList
- 15839
- Advantage
- 69
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44689
- Advantage
- 61
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- chenyj@titansci.com
- Country
- China
- ProdList
- 14103
- Advantage
- 59
- Tel
- 19951945301
- Fax
- +86-25-83453306
- info@chemlin.com.cn
- Country
- China
- ProdList
- 19185
- Advantage
- 64
- Tel
- 021-50135380
- shchemsky@sina.com
- Country
- China
- ProdList
- 32321
- Advantage
- 50
- Tel
- Fax
- E-Mail Inquiry
- info@syntechem.com
- Country
- China
- ProdList
- 12984
- Advantage
- 57
- Tel
- 400 638 7771
- sales@heowns.com
- Country
- China
- ProdList
- 14435
- Advantage
- 57
- Tel
- 86-21-63210123
- Fax
- 86-21-63290778 86-21-63218885
- sj_scrc@sinopharm.com
- Country
- China
- ProdList
- 9815
- Advantage
- 79
- Tel
- 021-021-021-67601398-809-809-809 15221380277
- Fax
- 021-57711696
- marketing_china@spectrumchemical.com
- Country
- China
- ProdList
- 9658
- Advantage
- 60
- Tel
- 0411-62910999 13889544652
- sales@meilune.com
- Country
- China
- ProdList
- 4727
- Advantage
- 58
- Tel
- 021-61312847 13636370518
- Fax
- 021-55068248
- shyysw007@163.com
- Country
- China
- ProdList
- 4940
- Advantage
- 60
- Tel
- 010-56205725
- Fax
- 010-65763397
- waley188@sohu.com
- Country
- China
- ProdList
- 12335
- Advantage
- 58
- Tel
- +86-21-65211385-8001 36031160
- Fax
- +86-21-65211385-8004
- sales@shruji.com
- Country
- China
- ProdList
- 3224
- Advantage
- 55
- Tel
- +86-21-5821 5861
- Fax
- +86-21-5106 2861
- sales@letopharm.com
- Country
- China
- ProdList
- 70
- Advantage
- 55
- Tel
- 18016401466
- Fax
- QQ: 1375988926
- sales@letopharm.com
- Country
- China
- ProdList
- 213
- Advantage
- 58
- Tel
- 400-0066400 13621662912
- Fax
- 021-55660885
- 422131432@qq.com
- Country
- China
- ProdList
- 9978
- Advantage
- 55
- Tel
- 021-54359730 400-008-9730
- Fax
- 021-54353864
- info@chemxyz.com
- Country
- China
- ProdList
- 3991
- Advantage
- 60
- Tel
- 0512-87182056 18013166090
- Fax
- 0512-87182056
- lingling.qi@yacoo.com.cn
- Country
- China
- ProdList
- 7295
- Advantage
- 60
- Tel
- 021-60345187 13671753212
- Fax
- 021-34702061
- lzz841106@aliyun.com
- Country
- China
- ProdList
- 10274
- Advantage
- 55
- Tel
- 15221275939 15221275939
- Fax
- 021-50706099
- shenlinxing@macklin.cn
- Country
- China
- ProdList
- 16166
- Advantage
- 55
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
- Country
- China
- ProdList
- 51456
- Advantage
- 80
- Tel
- 4000-819-385 010-62329685 13718666987
- Fax
- 010-62340519
- Country
- China
- ProdList
- 1971
- Advantage
- 55
- Tel
- 19542790274 19542790274
- Fax
- QQ1456295541
- 2119559397@qq.com
- Country
- China
- ProdList
- 885
- Advantage
- 50
- Tel
- 0317-5296180 15533709196
- Fax
- 0317-5106596
- sale@enkepharma.com
- Country
- China
- ProdList
- 2007
- Advantage
- 55
- Tel
- 010-50973130 4009686088
- 3193328036@qq.com
- Country
- China
- ProdList
- 29764
- Advantage
- 68
- Tel
- 010-60605840 18892239720
- Fax
- 010-60605840
- psaitong@jm-bio.com
- Country
- China
- ProdList
- 12306
- Advantage
- 58
- Tel
- +86-530-529 6766，+86-15666160102 15666160102
- Fax
- 0530-529 6766
- info@chuangli-chem.com
- Country
- China
- ProdList
- 899
- Advantage
- 55
- Tel
- 13672434928
- Fax
- -
- 3307355104@qq.com
- Country
- China
- ProdList
- 3650
- Advantage
- 58
- Tel
- 025-58851090 13611564524
- Fax
- (6)02557626880
- lwan@aikonchem.com
- Country
- China
- ProdList
- 15951
- Advantage
- 58
- Tel
- 021-61469567 13482353728
- Fax
- 021-61161605
- sales@fdc-chemical.com
- Country
- China
- ProdList
- 15006
- Advantage
- 58
- Tel
- 400-6387771-6037 18920794737
- sales@heowns.com
- Country
- China
- ProdList
- 23083
- Advantage
- 60
- Tel
- 0371-63315541 13323832564
- Fax
- QQ:3001332135
- 3001332135@qq.com
- Country
- China
- ProdList
- 10034
- Advantage
- 58
- Tel
- 010-010-010-62971590 18548936886
- Fax
- 010-62340519
- jack@oka-vip.com
- Country
- China
- ProdList
- 6897
- Advantage
- 58
- Tel
- 13739298932
- 531626407@qq.com
- Country
- China
- ProdList
- 3004
- Advantage
- 58
- Tel
- +86-400-002-6226 +86-13028896684;
- sales@rrkchem.com
- Country
- China
- ProdList
- 57423
- Advantage
- 58
- Tel
- 020-31155029 18902330969
- Fax
- 020-31155029
- sales@tomums.cn
- Country
- China
- ProdList
- 4696
- Advantage
- 58
- Tel
- 18081075745
- chemflowtech@sina.com
- Country
- China
- ProdList
- 1886
- Advantage
- 58
- Tel
- +86-400-0216110 +8615958047586
- Fax
- 0086-21-33275002
- sales@allfluoro.com
- Country
- China
- ProdList
- 11359
- Advantage
- 58
- Tel
- +8617531153977
- allison@yan-xi.com
- Country
- China
- ProdList
- 5855
- Advantage
- 58
- Tel
- +86-29-89586680 +86-15129568250
- 1026@dideu.com
- Country
- China
- ProdList
- 22787
- Advantage
- 58
- Tel
- 15921040873
- 1434142450@qq.com
- Country
- CHINA
- ProdList
- 7649
- Advantage
- 58
- Tel
- 15901914505 15901914505
- Fax
- 021-54389085
- 3187892335@qq.com
- Country
- China
- ProdList
- 9092
- Advantage
- 58
- Tel
- 86-13657291602
- Fax
- 027-59338440
- linda@hubeijusheng.com
- Country
- CHINA
- ProdList
- 22963
- Advantage
- 58
- Tel
- +86-023-6139-8061 +86-86-13650506873
- sales@chemdad.com
- Country
- China
- ProdList
- 39894
- Advantage
- 58
- Tel
- 021-54721350 13524668266
- Fax
- 021-5
- 2881505714@qq.com
- Country
- China
- ProdList
- 7872
- Advantage
- 58
- Tel
- 021-61998208 18217752821
- Fax
- 021-37680378
- sales@klbio.cn
- Country
- China
- ProdList
- 9618
- Advantage
- 58
- Tel
- +86-29-87569262 +86-15003564040
- Fax
- 029-88380327
- 1087@dideu.com
- Country
- China
- ProdList
- 3167
- Advantage
- 58
- Tel
- 88888888888
- hongquchem@qq.com
- Country
- China
- ProdList
- 5132
- Advantage
- 58
More
Less
View Lastest Price from 6-HYDROXYDOPAMINE HYDROBROMIDE manufacturers
Hebei Weibang Biotechnology Co., Ltd
- Product
- 6-HYDROXYDOPAMINE HYDROBROMIDE 636-00-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-28
Career Henan Chemical Co
- Product
- 6-HYDROXYDOPAMINE HYDROBROMIDE 636-00-0
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 95%-99%
- Supply Ability
- 100kg
- Release date
- 2018-12-24
636-00-0, 6-HYDROXYDOPAMINE HYDROBROMIDERelated Search:
Formamidinium Bromide
Pyridinium tribromide
ETHYLAMINE HYDROBROMIDE
KEMPTIDE
Hydrogen bromide
6-HYDROXYDOPAMINE HYDROBROMIDE*W/ASCORBIC ACID
6-HYDROXYDOPAMINE HYDROBROMIDE WITH
2-(2-aminoethyl)phenol
BCMCM-CAGED 8-BR-CAMP, 2,5-HYDRATE
Dopamine
BCMCM-CAGED 8-BR-CGMP, TRIHYDRATE
1,2,4-Benzenetriol
oxidopamine
6-HYDROXYDOPAMINE HYDROBROMIDE