CATHEPSIN S
- Product Name
- CATHEPSIN S
- CAS No.
- 71965-46-3
- Chemical Name
- CATHEPSIN S
- Synonyms
- CTSS;CASS;MGC3886;FLJ50259;CATHEPSIN S;EC 3.4.22.27;Mini Sample Mouse CTSS;Cathepsin S Active human;CATHEPSIN S, BOVINE SPLEEN;Cathepsin S from Human, recombinant
- CBNumber
- CB2295857
- Formula Weight
- 0
- MOL File
- Mol file
CATHEPSIN S Property
- storage temp.
- -70°C
- form
- aqueous solution
- color
- White to off-white
- biological source
- human
- Specific Activity
- ≥8100pmol/min-μg
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P201Obtain special instructions before use.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313IF exposed or concerned: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- SRP0292
- Product name
- Cathepsin S Active human
- Purity
- recombinant, expressed in FreeStyle? 293-F cells, ≥90% (SDS-PAGE)
- Packaging
- 10μG
- Price
- $673
- Updated
- 2025/07/31
- Product number
- 382559
- Product name
- CTSS
- Packaging
- 96Tests
- Price
- $729
- Updated
- 2021/12/16
- Product number
- 139671
- Product name
- CTSS
- Packaging
- 200ul
- Price
- $442
- Updated
- 2021/12/16
- Product number
- 355064
- Product name
- CTSS
- Packaging
- 48Tests
- Price
- $588
- Updated
- 2021/12/16
- Product number
- 355065
- Product name
- CTSS
- Packaging
- 48Tests
- Price
- $588
- Updated
- 2021/12/16
CATHEPSIN S Chemical Properties,Usage,Production
Uses
Active human cathepsin S is useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Active human cathepsin S has been used in a study to assess the pathogenesis of Alzheimer′s disease. Active human cathepsin S has also been used in a study to investigate the optimization of selectivity of Azepanone-based inhibitors.
General Description
Human cathepsin S (GenBank Accession No. NM_004079.3), CD33 signal peptide(amino acids 1-16) + cathepsin S (amino acids 17-331), with C-terminal HIS tag, MW = 37 kDa, expressed in FreeStyle 293-F cells.
Biological Activity
Cathepsin S, as a lysosomal protease, facilitates the breakdown of unwanted and damaged proteins in the endo-lysosomal pathway. Moreover, it plays specific roles, such as contributing to major histocompatibility complex (MHC) class II antigen presentation by aiding in the degradation of the invariant chain. Dysregulation of cathepsin S has been associated with various pathological conditions, such as cancer, arthritis, and cardiovascular disease. Cathepsin S is useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. It is also used as a biomarker for atherosclerosis, diabetes, adiposity, and atherogenesis. Moreover, it acts as a promising target against brain-penetrating and for the treatment of multiple sclerosis and neuropathic pain.
CATHEPSIN S Preparation Products And Raw materials
Raw materials
Preparation Products
CATHEPSIN S Suppliers
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- 027-65317797 15926423062
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- 21-20338288
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- China
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- 025-58868422
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