ETHYL 1H-INDAZOLE-5-CARBOXYLATE
- Product Name
- ETHYL 1H-INDAZOLE-5-CARBOXYLATE
- CAS No.
- 192944-51-7
- Chemical Name
- ETHYL 1H-INDAZOLE-5-CARBOXYLATE
- Synonyms
- Ethyl Indazole-5-carboxylate;ETHYL 1H-INDAZOLE-5-CARBOXYLAT;5-(Ethoxycarbonyl)-1H-indazole;EthylIndazole-5-carboxylate>ETHYL 1H-INDAZOLE-5-CARBOXYLATE;Ethyl1H-indazole-5-carboxylate,95%;Indazole-5-carboxylic Acid Ethyl Ester;1H-INDAZOLE-5-CARBOXYLIC ACID ETHYL ESTER;1H-Indazole-5-carboxylicacid,ethylester(9CI)
- CBNumber
- CB2298449
- Molecular Formula
- C10H10N2O2
- Formula Weight
- 190.2
- MOL File
- 192944-51-7.mol
ETHYL 1H-INDAZOLE-5-CARBOXYLATE Property
- Melting point:
- 122-124℃
- Boiling point:
- 353.9±15.0 °C(Predicted)
- Density
- 1.272±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- form
- powder to crystal
- pka
- 12.81±0.40(Predicted)
- color
- White to Yellow to Orange
Safety
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39
- HS Code
- 29339900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- E1067
- Product name
- Ethyl Indazole-5-carboxylate
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $126
- Updated
- 2025/07/31
- Product number
- E1067
- Product name
- Ethyl Indazole-5-carboxylate
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $378
- Updated
- 2025/07/31
- Product number
- E937060
- Product name
- Ethyl1H-Indazole-5-carboxylate
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- OR61035
- Product name
- Ethyl1H-indazole-5-carboxylate
- Purity
- 95%
- Packaging
- 1g
- Price
- $56
- Updated
- 2021/12/16
- Product number
- 4H23-1-55
- Product name
- Ethyl 1H-indazole-5-carboxylate
- Purity
- 95%
- Packaging
- 1g
- Price
- $61
- Updated
- 2021/12/16
ETHYL 1H-INDAZOLE-5-CARBOXYLATE Chemical Properties,Usage,Production
Synthesis
192944-50-6
192944-51-7
Ethyl 1-acetyl-1H-indazole-5-carboxylate was used as a raw material, which was dissolved in a mixed solvent consisting of concentrated hydrochloric acid (15 mL), water (15 mL) and ethanol (30 mL), and the reaction was stirred for 4 hours at room temperature. Upon completion of the reaction, the pH of the reaction mixture was adjusted to slightly basic with 25% ammonia. Subsequently, the alkalized mixture was extracted with chloroform. The organic phases were combined and purified by hexane crystallization. After completion of crystallization, the resulting crystals were collected by filtration and dried to give the final ethyl 5-indazolecarboxylate (6.45 g, 48% yield) as a light brown powder.
References
[1] Journal of Medicinal Chemistry, 2000, vol. 43, # 1, p. 41 - 58
[2] Patent: US2013/79306, 2013, A1. Location in patent: Paragraph 0286
ETHYL 1H-INDAZOLE-5-CARBOXYLATE Preparation Products And Raw materials
Raw materials
Preparation Products
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