ChemicalBook > CAS DataBase List > ETHYL 1H-INDAZOLE-5-CARBOXYLATE

ETHYL 1H-INDAZOLE-5-CARBOXYLATE

Product Name
ETHYL 1H-INDAZOLE-5-CARBOXYLATE
CAS No.
192944-51-7
Chemical Name
ETHYL 1H-INDAZOLE-5-CARBOXYLATE
Synonyms
Ethyl Indazole-5-carboxylate;ETHYL 1H-INDAZOLE-5-CARBOXYLAT;5-(Ethoxycarbonyl)-1H-indazole;EthylIndazole-5-carboxylate>ETHYL 1H-INDAZOLE-5-CARBOXYLATE;Ethyl1H-indazole-5-carboxylate,95%;Indazole-5-carboxylic Acid Ethyl Ester;1H-INDAZOLE-5-CARBOXYLIC ACID ETHYL ESTER;1H-Indazole-5-carboxylicacid,ethylester(9CI)
CBNumber
CB2298449
Molecular Formula
C10H10N2O2
Formula Weight
190.2
MOL File
192944-51-7.mol
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ETHYL 1H-INDAZOLE-5-CARBOXYLATE Property

Melting point:
122-124℃
Boiling point:
353.9±15.0 °C(Predicted)
Density 
1.272±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
form 
powder to crystal
pka
12.81±0.40(Predicted)
color 
White to Yellow to Orange
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Safety

Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
E1067
Product name
Ethyl Indazole-5-carboxylate
Purity
>98.0%(GC)
Packaging
1g
Price
$126
Updated
2025/07/31
TCI Chemical
Product number
E1067
Product name
Ethyl Indazole-5-carboxylate
Purity
>98.0%(GC)
Packaging
5g
Price
$378
Updated
2025/07/31
TRC
Product number
E937060
Product name
Ethyl1H-Indazole-5-carboxylate
Packaging
50mg
Price
$60
Updated
2021/12/16
Apolloscientific
Product number
OR61035
Product name
Ethyl1H-indazole-5-carboxylate
Purity
95%
Packaging
1g
Price
$56
Updated
2021/12/16
SynQuest Laboratories
Product number
4H23-1-55
Product name
Ethyl 1H-indazole-5-carboxylate
Purity
95%
Packaging
1g
Price
$61
Updated
2021/12/16
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ETHYL 1H-INDAZOLE-5-CARBOXYLATE Chemical Properties,Usage,Production

Synthesis

192944-50-6

192944-51-7

Ethyl 1-acetyl-1H-indazole-5-carboxylate was used as a raw material, which was dissolved in a mixed solvent consisting of concentrated hydrochloric acid (15 mL), water (15 mL) and ethanol (30 mL), and the reaction was stirred for 4 hours at room temperature. Upon completion of the reaction, the pH of the reaction mixture was adjusted to slightly basic with 25% ammonia. Subsequently, the alkalized mixture was extracted with chloroform. The organic phases were combined and purified by hexane crystallization. After completion of crystallization, the resulting crystals were collected by filtration and dried to give the final ethyl 5-indazolecarboxylate (6.45 g, 48% yield) as a light brown powder.

References

[1] Journal of Medicinal Chemistry, 2000, vol. 43, # 1, p. 41 - 58
[2] Patent: US2013/79306, 2013, A1. Location in patent: Paragraph 0286

ETHYL 1H-INDAZOLE-5-CARBOXYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

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ETHYL 1H-INDAZOLE-5-CARBOXYLATE Suppliers

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192944-51-7, ETHYL 1H-INDAZOLE-5-CARBOXYLATERelated Search:

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