Tralkoxydim Property

Melting point:

106°

Boiling point:

467.02°C (rough estimate)

Density 

1.1213 (rough estimate)

refractive index 

1.5614 (estimate)

Flash point:

>100 °C

storage temp. 

0-6°C

solubility 

soluble in dichloromethane,Toluene,Acetone

pka

4.20±0.25(Predicted)

color 

Light yellow to Yellow to Orange

Merck 

14,9564

BRN 

8577523

LogP

4.460

CAS DataBase Reference

87820-88-0(CAS DataBase Reference)

EPA Substance Registry System

Tralkoxydim (87820-88-0)

Safety

Hazard Codes 

Xn

Risk Statements 

22

RIDADR 

UN 3077 9 / PGIII

WGK Germany 

3

RTECS 

GW7191600

HazardClass 

9

PackingGroup 

III

HS Code 

29280000

Hazardous Substances Data

87820-88-0(Hazardous Substances Data)

Toxicity

LD50 orally in male and female rats, male and female mice, male rabbit (mg/kg): 1324, 934, 1231, 1100, 519; dermally in male and female rats: >2000, >2000 mg/kg (Warner 1987)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H351Suspected of causing cancer

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

Tralkoxydim Chemical Properties,Usage,Production

Physical and Chemical Properties

Appearance: White tasteless crystalline solid
Melting Point: 106℃
Saturated Vapor Pressure: 4×10-7Pa (<0.013×10-3Pa 20℃)
Solubility: 4×10-7Pa (<0.013×10-3Pa 20℃) in dichloromethane at 24℃, 213g/L in methylbenzene at 24℃, 110g/L in ethyl acetate at 24℃, 89g/L in acetone at 24℃, 25g/L in methanol at 24℃, 18g/L in hexane at 24℃.
6mg/L (pH=6.5) and 5mg/L (pH=5.0) in water at 20℃

InChI Code

1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,22H,6-7,10-11H2,1-5H3

Toxicity

P.O. acute toxicity： LD50=1324mg/kg for male rats, LD50=934mg/kg for female rats,  LD50=1321mg/kg for male mice, LD50=1100mg/kg for female mice, LD50>519mg/kg for rabbits.
Non-effect dose for rats in three-month feed test is 12.5mg/kg. LD50=3020mg/kg for mallard, LD50=4430mg/kg for partridge.
Acute percutaneous toxicity: LD50>2000mg/kg for male and female rats.
Acute inhalation toxicity: LC50>3467mg/m3 for male and female rats.
It has mild irritation on eyes and skin. No allergic effect on cavy.
No teratogenesis effect has been observed yet.
LC50>7.2mg/L (96h) for rainbow trout, LC50>8.2mg/L (96h) for Cyprinus carpio var.

Application

Tralkoxydim is a kind of highly selective herbicide with inward absorption and conduction ability. It’s used on a variety of graminaceous weeds in barley and wheat fields. It is rapidly absorbed and transferred throughout all parts of the weeds after foliar spray. The weeds will soon turn pale and wither. The general dosage is 150～350g effective constituent/hm2 . 200～350g effective constituent /hm2 of tralkoxydim applied from early growth period to elongation stage will be effective on the prevention and control of wild oat weeds.

Synthesis

The product of the reaction between 2,4,6-Trimethylbenzaldehyde and acetone react with diethyl malonate to generate an intermediate. The intermediate is transformed into 3-hydroxy-5-（2',4',6'-trimethylphenyl）-cyclohexyl-2-alkenyl-1-ketone after hydrolysis, cyclization and decarboxylation. Then it reacts with propionic anhydride in the presence of sodium methanol. The product reacts with ethoxyamine hydrochloride to generate methoxyphenone.

Uses

Post-emergent herbicide.

Definition

ChEBI: Tralkoxydim is a mixture.

Agricultural Uses

Herbicide: Tralkoxydim is a post-emergent herbicide applied to actively growing weeds in wheat, barley, triticale and cereal rye to control wild oats, green foxtail, yellow foxtail, annual ryegrass and Persian darnel. Registered for use in EU countries. Registered for use in the U.S.

Trade name

ACHIEVE®; ACHIEVE®-40DG; ALPHA GRASP®; ICI-A 604®; PP 604®; SPLENDOR®