ChemicalBook > CAS DataBase List > Axitinib Impurity a

Axitinib Impurity a

Product Name
Axitinib Impurity a
CAS No.
1347304-18-0
Chemical Name
Axitinib Impurity a
Synonyms
Axitinib C;PF03482595);Axitinib M12;Axitinib Sulfoxide;Axitinib Impurity a;Axitinib metabolite M12;Axitinib sulfoxide (AG028458;N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfinyl]benzamide;N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfinyl]benzamide;Benzamide, N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfinyl]-
CBNumber
CB23038983
Molecular Formula
C22H18N4O2S
Formula Weight
402.47
MOL File
1347304-18-0.mol
More
Less

Axitinib Impurity a Property

Melting point:
>225 (dec.)
Boiling point:
720.6±60.0 °C(Predicted)
Density 
1.43±0.1 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
DMSO (Slightly), Methanol (Slightly, Heated)
form 
Solid
pka
11.70±0.40(Predicted)
color 
Light Yellow
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P281Use personal protective equipment as required.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
28042
Product name
Axitinib Sulfoxide
Packaging
1mg
Price
$62
Updated
2024/03/01
Cayman Chemical
Product number
28042
Product name
Axitinib Sulfoxide
Packaging
5mg
Price
$211
Updated
2024/03/01
TRC
Product number
A794885
Product name
AxitinibSulfoxide
Packaging
10mg
Price
$345
Updated
2021/12/16
AK Scientific
Product number
5029EA
Product name
Axitinibsulfoxide
Packaging
1mg
Price
$166
Updated
2021/12/16
More
Less

Axitinib Impurity a Chemical Properties,Usage,Production

Description

Axitinib sulfoxide is a major inactive metabolite of the tyrosine kinase inhibitor axitinib . It is formed from axitinib primarily by the cytochrome P450 (CYP) isoform CYP3A4 with minor contributions from CYP3A5 and CYP2C19.

Uses

Axitinib Sulfoxide is a major metabolite of Axitinib (A794650), a tyrosine kinase inhibitor. Axitinib is used in cancer therapy.

Axitinib Impurity a Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Axitinib Impurity a Suppliers

China 48 India 4 United States 7 Global 59
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-83725681-603
Fax
+86 755 28094224
Country
China
ProdList
4505
Advantage
50
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17993
Advantage
56
ATK CHEMICAL COMPANY LIMITED
Tel
3429815786 13301662590
Fax
+86-21-51619052
Email
sales@atkchemical.com
Country
China
ProdList
10004
Advantage
55
Shanghai Chaolan Chemical Technology Center
Tel
QQ:65489617 15618227136
Fax
21-5161 9052
Email
info@SuperLan-chem.com
Country
China
ProdList
9838
Advantage
58
Roark Standards
Tel
0755-83552066 15986688328
Fax
0755-83552066
Email
service@roarkstandards.com
Country
China
ProdList
1443
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131980
Advantage
58
Hubei Yangxin Medical Technology Co., Ltd.
Tel
15374522761
Fax
QQ:2853117752
Email
3003392093@qq.com
Country
China
ProdList
8043
Advantage
55
Aikon International Limited
Tel
025-58851090 13611564524
Fax
(6)02557626880
Email
lwan@aikonchem.com
Country
China
ProdList
15952
Advantage
58
SHANGHAI FDC-CHEMICAL CO.,LTD
Tel
021-61469567 18521078705
Fax
021-61161605
Email
sales@fdc-chemical.com
Country
China
ProdList
19983
Advantage
58
Shanghai Han-Xiang Chemical Co., Ltd.
Tel
15971444841
Fax
18327183813
Email
amber@biochempartner.com
Country
China
ProdList
3063
Advantage
58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6870
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 13028896684
Email
sales@rrkchem.com
Country
China
ProdList
56039
Advantage
58
TOSUN PHARM
Tel
020-61855200 13326451905
Email
2881290884@qq.com
Country
China
ProdList
7539
Advantage
58
Jinan Baizhou Biological Technology Co., Ltd.
Tel
0531-88987162 18615427082
Email
2823799053@qq.com
Country
China
ProdList
497
Advantage
58
ANHUI WITOP BIOTECH CO., LTD
Tel
+8615255079626
Email
eric@witopchemical.com
Country
China
ProdList
23556
Advantage
58
Guangzhou Dreampharm Biotechnology Co., Ltd.
Tel
020-36607679 17825480238
Fax
QQ 3008233717
Email
3008233717@qq.com
Country
China
ProdList
9843
Advantage
12
Jinan blalong chemical co. LTD
Tel
2710913286@.com
Email
1513643261@qq.com
Country
China
ProdList
14253
Advantage
58
Hefei fuya biotechnology co. LTD
Tel
18096409024
Email
sales02@foreversyn.com
Country
China
ProdList
1957
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11289
Advantage
58
PCL - Business, Laboratory Pharmaceutical
Tel
19150123681
Fax
QQ:3008022628
Email
Hu.xinyue@purechemland.com
Country
China
ProdList
3567
Advantage
58
Wuxi Minglu Medicine technology Co.,Ltd.
Tel
0510-88726693
Fax
0510-88726693
Email
3204601684@qq.com
Country
China
ProdList
1896
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
4008210725 4008210725
Email
malulu@leyan.com
Country
China
ProdList
55023
Advantage
58
Shenzhen Hengfeng Wanda Pharmaceutical Technology Co., Ltd
Tel
0755-22677922 18126518403
Fax
518109
Email
2851922760@qq.com
Country
China
ProdList
5043
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44843
Advantage
58
Hubei Ruinuo Pharmaceutical Technology Co., Ltd
Tel
13165688766
Fax
0714-5316360
Email
3008058303@qq.com
Country
China
ProdList
5000
Advantage
58
Guangzhou Juntang Technology Co., Ltd
Tel
020-36607679 13502246435
Email
sales@dmstandards.com
Country
China
ProdList
10951
Advantage
58
Changzhou Furuisi Biotechnology Co., Ltd
Tel
0519-85524369
Email
3477467573@qq.com
Country
China
ProdList
8618
Advantage
58
Heyuan broad spectrum Biotechnology Co., Ltd
Tel
0762-3393039 18023108599
Email
2853058244@qq.com
Country
China
ProdList
982
Advantage
58
Foshan Treasure Biotechnology Co., Ltd
Tel
0757-85921206 18520245316
Email
2329783215@qq.com
Country
China
ProdList
12664
Advantage
58
Molcoo Chemicals Inc.
Tel
18627923403 18627753421
Email
3001006472@qq.com
Country
China
ProdList
8780
Advantage
58
InvivoChem
Tel
13549236410
Email
sales@invivochem.cn
Country
China
ProdList
6749
Advantage
58
Hunan Zengda Biological Technology Co., LTD
Tel
18711085600
Email
1652923704@qq.com
Country
China
ProdList
4583
Advantage
58
Shenzhen Roark Pharma-Tec Co., Ltd.
Tel
13128912434
Email
2880126944@qq.com
Country
China
ProdList
2579
Advantage
58
Cato Research Chemicals Inc.
Tel
020-81960175-877 18933936954
Email
tianwen.zhan@cato-chem.com
Country
China
ProdList
7721
Advantage
58
Shanghai YuZn Pharm. Technology Co.,Ltd.
Tel
15921286451; 15921286451
Email
2010681527@qq.com
Country
China
ProdList
5062
Advantage
58
Shanghai Yiyan Biotechnology Co. , Ltd.
Tel
021-69985186 13611928337
Email
3427709316@qq.com
Country
China
ProdList
7984
Advantage
58
Shenzhen Excellent Biomedical Technology Co., Ltd.
Tel
18318671572
Email
2850803126@qq.com
Country
China
ProdList
4993
Advantage
58
Tan-Mo Technology Co., Ltd.
Tel
19850211281
Email
qiann@gbw-china.com
Country
China
ProdList
1980
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
8740
Advantage
58
Shanghai Zerui Biotechnology Co., Ltd.
Tel
021-54580889 18321124657
Fax
021-54580889
Email
731997554@qq.com
Country
China
ProdList
10614
Advantage
58
Shandong Mopai Biotechnology Co., Ltd
Tel
13053322091 13053322091
Email
admin@mopaikeji.com
Country
China
ProdList
10974
Advantage
58
Hubei De'ao Chemical Research Pharmaceutical Technology Co., Ltd
Tel
18502726233
Email
3641133981@qq.com
Country
China
ProdList
9400
Advantage
58
Nantong Hanfang Biotechnology Co. , Ltd.
Tel
3674309880
Email
hanfangpharma@126.com
Country
China
ProdList
30968
Advantage
58
Hubei Moco Chemical Co., Ltd.
Tel
17386083646
Fax
QQ：3001051413
Email
2853567991@qq.com
Country
China
ProdList
10544
Advantage
58
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.com
Country
China
ProdList
24246
Advantage
58
Zibo Hangyu Biotechnology Development Co., Ltd
Tel
+86-0533-2185556 +8617865335152
Email
Mandy@hangyubiotech.com
Country
China
ProdList
11013
Advantage
58
China National Standard Pharmaceutical Corporation Limited
Tel
+8615391658522
Email
overseasales@yongstandards.com
Country
China
ProdList
11927
Advantage
58
Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@zzsrm.com
Country
CHINA
ProdList
6846
Advantage
58

1347304-18-0, Axitinib Impurity aRelated Search:

Axitinib Axitinib Impurity b BenzaMide, 2-[(3-iodo-1H-indazol-6-yl)thio]-N-Methyl- 3,6-DIIODO (1H)INDAZOLE Axitinib Impurity 3 Axitinib-13C-d3 Axitinib Impurity d Axitinib Impurity 23 Axitinib Impurity 26 Axitinib Impurity 10 Axitinib Impurity 4 Axitinib Impurity 20 Axitinib Impurity 18 Axitinib Impurity 13 2-(1H-indazol-6-ylthio)-N-Methyl- BenzaMide Axitinib Impurity 3 Axitinib Impurity 14 Axitinib Impurity 19

  • Axitinib Impurity a
  • Axitinib Sulfoxide
  • N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfinyl]benzamide
  • N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfinyl]benzamide
  • Axitinib Impurity 5/Axitinib Sulfoxide/N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfinyl]-benzamide
  • Benzamide, N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfinyl]-
  • Axitinib C
  • Axitinib sulfoxide (AG028458
  • PF03482595)
  • Axitinib M12
  • Axitinib metabolite M12
  • (E)-N-Methyl-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)sulfinyl)benzamide (Axitinib Impurity)
  • 1347304-18-0