ChemicalBook > CAS DataBase List > 2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamide
2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamide
- Product Name
- 2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamide
- CAS No.
- 1375466-18-4
- Chemical Name
- 2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamide
- Synonyms
- ACY-775;ACY-77;CS-2821;ACY-775 (ACY 775;ACY-775; ACY 775; ACY775.;ACY-775,Histone deacetylases,inhibit,Inhibitor,ACY 775,HDAC,ACY775;5-Pyrimidinecarboxamide, 2-[[1-(3-fluorophenyl)cyclohexyl]amino]-N-hydroxy-;2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamide
- CBNumber
- CB23042717
- Molecular Formula
- C17H19FN4O2
- Formula Weight
- 330.36
- MOL File
- 1375466-18-4.mol
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2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamide Property
- Density
- 1.342±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- solubility
- DMSO:35.33(Max Conc. mg/mL);106.94(Max Conc. mM)
DMF:20.0(Max Conc. mg/mL);60.54(Max Conc. mM)
DMF:PBS (pH 7.2) (1:4):0.2(Max Conc. mg/mL);0.61(Max Conc. mM)
Ethanol:34.5(Max Conc. mg/mL);104.43(Max Conc. mM) - form
- A solid
- pka
- 7.74±0.10(Predicted)
- color
- White to off-white
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N-Bromosuccinimide Price
TRC
- Product number
- A305320
- Product name
- ACY-775
- Packaging
- 10mg
- Price
- $235
- Updated
- 2021/12/16
Adipogen Life Sciences
- Product number
- AG-CR1-3903-M005
- Product name
- ACY-775
- Purity
- ≥95%(HPLC)
- Packaging
- 5mg
- Price
- $490
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-7689
- Product name
- ACY-775
- Purity
- 99.83%
- Packaging
- 50mg
- Price
- $588
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-7689
- Product name
- ACY-775
- Purity
- 99.83%
- Packaging
- 2mg
- Price
- $108
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-7689
- Product name
- ACY-775
- Purity
- 99.83%
- Packaging
- 5mg
- Price
- $144
- Updated
- 2021/12/16
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2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamide Chemical Properties,Usage,Production
Uses
ACY-775 is a novel histone deacetylase 6-selective (HDAC6) inhibitor with antidepressant and pro-cognitive properties. ACY-775 inhibits HDAC6 with low nanomolar potency and a selectivity of 60- to 1500-fold over class I HDACs.
2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamide Preparation Products And Raw materials
Raw materials
Preparation Products
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2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamide Suppliers
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