2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamide

ChemicalBook > CAS DataBase List > 2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamide

2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamide

Product Name: 2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamide
CAS No.: 1375466-18-4
Chemical Name: 2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamide
Synonyms: ACY-775;ACY-77;CS-2821;ACY-775 (ACY 775;ACY-775; ACY 775; ACY775.;ACY-775,Histone deacetylases,inhibit,Inhibitor,ACY 775,HDAC,ACY775;5-Pyrimidinecarboxamide, 2-[[1-(3-fluorophenyl)cyclohexyl]amino]-N-hydroxy-;2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamide
CBNumber: CB23042717
Molecular Formula: C17H19FN4O2
Formula Weight: 330.36
MOL File: 1375466-18-4.mol

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2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamide Property

Density: 1.342±0.06 g/cm3(Predicted)
storage temp.: 2-8°C(protect from light)
solubility: DMSO:35.33(Max Conc. mg/mL);106.94(Max Conc. mM)
DMF:20.0(Max Conc. mg/mL);60.54(Max Conc. mM)
DMF:PBS (pH 7.2) (1:4):0.2(Max Conc. mg/mL);0.61(Max Conc. mM)
Ethanol:34.5(Max Conc. mg/mL);104.43(Max Conc. mM)
form: A solid
pka: 7.74±0.10(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: A305320
Product name: ACY-775
Packaging: 10mg
Price: $235
Updated: 2021/12/16

Adipogen Life Sciences

Product number: AG-CR1-3903-M005
Product name: ACY-775
Purity: ≥95%(HPLC)
Packaging: 5mg
Price: $490
Updated: 2021/12/16

ChemScene

Product number: CS-7689
Product name: ACY-775
Purity: 99.83%
Packaging: 50mg
Price: $588
Updated: 2021/12/16

ChemScene

Product number: CS-7689
Product name: ACY-775
Purity: 99.83%
Packaging: 2mg
Price: $108
Updated: 2021/12/16

ChemScene

Product number: CS-7689
Product name: ACY-775
Purity: 99.83%
Packaging: 5mg
Price: $144
Updated: 2021/12/16

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2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamide Chemical Properties,Usage,Production

Uses

ACY-775 is a novel histone deacetylase 6-selective (HDAC6) inhibitor with antidepressant and pro-cognitive properties. ACY-775 inhibits HDAC6 with low nanomolar potency and a selectivity of 60- to 1500-fold over class I HDACs.

2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamide Preparation Products And Raw materials

Raw materials

Preparation Products

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1375466-18-4, 2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamideRelated Search:

ACY-775

2-[1-(3-Fluoro-phenyl)-cyclohexylamino]-pyrimidine-5-carboxylic acid hydroxyamide

ACY-775; ACY 775; ACY775.

CS-2821

ACY-775 (ACY 775

ACY-77

5-Pyrimidinecarboxamide, 2-[[1-(3-fluorophenyl)cyclohexyl]amino]-N-hydroxy-

ACY-775,Histone deacetylases,inhibit,Inhibitor,ACY 775,HDAC,ACY775

1375466-18-4