ANTI-E2F-3
- Product Name
- ANTI-E2F-3
- Chemical Name
- ANTI-E2F-3
- Synonyms
- ANTI-E2F-3;Anti-KIAA0075;Anti-MGC104598;ANTI-HUMAN E2F-3;Anti-DKFZp686C18211;Anti-E2F transcription factor 3;Anti-E2F3 antibody produced in rabbit;Monoclonal Anti-E2F3 antibody produced in mouse
- CBNumber
- CB2304746
- Formula Weight
- 0
- MOL File
- Mol file
ANTI-E2F-3 Property
- storage temp.
- −20°C
- form
- buffered aqueous solution
- biological source
- rabbit
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- AV38089
- Product name
- Anti-E2F3 antibody produced in rabbit
- Purity
- affinity isolated antibody
- Packaging
- 100μL
- Price
- $524
- Updated
- 2024/03/01
ANTI-E2F-3 Chemical Properties,Usage,Production
Uses
Anti-E2F3 polyclonal antibody is used to tag E2F transcription factor 3 proteins for detection and quantitation by Western blotting and in cells and tissues by immunohistochemical (IHC) techniques. It is used as a probe to study the role of E2F transcription factor 3 in the regulation of cell growth, differentiation and cell death and as an oncogene.
Biological Activity
E2F3 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F2, have an additional cyclin binding domain. E2F3 binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner.
ANTI-E2F-3 Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-E2F-3 Suppliers
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