Mutant IDH1-IN-2

Product Name: Mutant IDH1-IN-2
CAS No.: 1429176-69-1
Chemical Name: Mutant IDH1-IN-2
Synonyms: Mutant IDH1-IN-2;Mutant IDH1 inhibitor 2;AG-881,Mutant IDH1-IN-2;Mutant IDH1-IN-2, 10 mM in DMSO;inhibit,Mutant IDH1 IN 2,Inhibitor,Mutant IDH-1-IN-2,Mutant IDH1IN2,Isocitrate Dehydrogenase (IDH);(S)-3-(2-(((S)-1-(4-((4,4-Difluoropiperidin-1-yl)methyl)phenyl)ethyl)amino)pyrimidin-4-yl)-4-isopropyloxazolidin-2-one;2-Oxazolidinone, 3-[2-[[(1S)-1-[4-[(4,4-difluoro-1-piperidinyl)methyl]phenyl]ethyl]amino]-4-pyrimidinyl]-4-(1-methylethyl)-, (4S)-
CBNumber: CB23048663
Molecular Formula: C24H31F2N5O2
Formula Weight: 459.53
MOL File: 1429176-69-1.mol

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Mutant IDH1-IN-2 Property

Boiling point:: 578.1±60.0 °C(Predicted)
Density: 1.27±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : 50 mg/mL (108.81 mM);Water : < 0.1 mg/mL (insoluble)
pka: 5.07±0.10(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene

Product number: CS-5119
Product name: MutantIDH1-IN-2
Purity: >98.0%
Packaging: 5mg
Price: $300
Updated: 2021/12/16

ChemScene

Product number: CS-5119
Product name: MutantIDH1-IN-2
Purity: >98.0%
Packaging: 10mg
Price: $500
Updated: 2021/12/16

ChemScene

Product number: CS-5119
Product name: MutantIDH1-IN-2
Purity: >98.0%
Packaging: 25mg
Price: $950
Updated: 2021/12/16

ChemScene

Product number: CS-5119
Product name: MutantIDH1-IN-2
Purity: >98.0%
Packaging: 50mg
Price: $1550
Updated: 2021/12/16

Crysdot

Product number: CD31003522
Product name: MutantIDH1-IN-2
Purity: 98+%
Packaging: 5mg
Price: $243
Updated: 2021/12/16

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Mutant IDH1-IN-2 Chemical Properties,Usage,Production

Uses

Mutant IDH1-IN-2 is a inhibitor of mutant Isocitrate dehydrogenase (IDH) proteins, with IC50 of in LS-MS biochemical assay, IC50 of 16.6 nM in Fluorescence biochemical assay. Target: Mutant IDH1 Mutant IDH1-IN-2 has a neomorphic activity and in the treatment of diseases or disorders associated with such mutant IDH proteins including, but not limited to, cell-proliferation disorders, such as cancer. More bioactivity information in Patent WO 2013046136A1 (Example 224).

IC 50

IDH1

References

[1] Huangshu, et al. 3-Pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH and their preparation

Mutant IDH1-IN-2 Preparation Products And Raw materials

Raw materials

Preparation Products

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Mutant IDH1-IN-2 Suppliers

China 27 United States 7 Global 34

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
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MedChemexpress LLC

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Guangzhou QiYun Biotechnology Co., Ltd.

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Musechem

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TargetMol Chemicals Inc.

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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

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Shanghai hongqu biomedical technology co. LTD

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1429176-69-1, Mutant IDH1-IN-2Related Search:

Mutant IDH1-IN-2

AG-881,Mutant IDH1-IN-2

Mutant IDH1 inhibitor 2

2-Oxazolidinone, 3-[2-[[(1S)-1-[4-[(4,4-difluoro-1-piperidinyl)methyl]phenyl]ethyl]amino]-4-pyrimidinyl]-4-(1-methylethyl)-, (4S)-

inhibit,Mutant IDH1 IN 2,Inhibitor,Mutant IDH-1-IN-2,Mutant IDH1IN2,Isocitrate Dehydrogenase (IDH)

Mutant IDH1-IN-2, 10 mM in DMSO

(S)-3-(2-(((S)-1-(4-((4,4-Difluoropiperidin-1-yl)methyl)phenyl)ethyl)amino)pyrimidin-4-yl)-4-isopropyloxazolidin-2-one

1429176-69-1

C24H31F2N5O2