ChemicalBook > CAS DataBase List > 1-azido-2-[2-(2-methoxyethoxy)ethoxy]ethane

1-azido-2-[2-(2-methoxyethoxy)ethoxy]ethane

Product Name
1-azido-2-[2-(2-methoxyethoxy)ethoxy]ethane
CAS No.
74654-06-1
Chemical Name
1-azido-2-[2-(2-methoxyethoxy)ethoxy]ethane
Synonyms
mPEG3-Azide;azido-mPEG3;N3-PEG3-O-ME;1-Azido-3,6,9-trioxadecane;2-(2-(2-methoxyethoxy)ethoxy)ethyl azide;1-azido-2-[2-(2-methoxyethoxy)ethoxy]ethane;Ethane, 1-(2-azidoethoxy)-2-(2-methoxyethoxy)-;1-Azido-2-(2-(2-methoxyethoxy)ethoxy)ethane - [A73309];mPEG3-N3/Ethane, 1-(2-azidoethoxy)-2-(2-methoxyethoxy)-
CBNumber
CB23059294
Molecular Formula
C7H15N3O3
Formula Weight
189.2123
MOL File
74654-06-1.mol
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1-azido-2-[2-(2-methoxyethoxy)ethoxy]ethane Property

Boiling point:
58 °C(Press: 0.01 Torr)
Density 
1.08 g/mL
refractive index 
n/D 1.4472
storage temp. 
2-8°C
form 
liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
901132
Product name
1-Azido-2-(2-(2-methoxyethoxy)ethoxy)ethane
Packaging
5G
Price
$295
Updated
2025/07/31
TRC
Product number
P999295
Product name
m-PEG3-azide
Packaging
2.5g
Price
$200
Updated
2021/12/16
TRC
Product number
P999295
Product name
m-PEG3-azide
Packaging
250mg
Price
$45
Updated
2021/12/16
Synthonix
Product number
A73309
Product name
1-Azido-2-(2-(2-methoxyethoxy)ethoxy)ethane
Purity
97%
Packaging
1g
Price
$57
Updated
2021/12/16
BroadPharm
Product number
BP-20973
Product name
m-PEG3-azide
Purity
98%
Packaging
250mg
Price
$140
Updated
2021/12/16
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1-azido-2-[2-(2-methoxyethoxy)ethoxy]ethane Chemical Properties,Usage,Production

Description

m-PEG3-azide is a PEG linker containing an azide group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

m-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. m-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

reaction suitability

reaction type: click chemistry

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

1-azido-2-[2-(2-methoxyethoxy)ethoxy]ethane Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 1-azido-2-[2-(2-methoxyethoxy)ethoxy]ethane manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
azido-mPEG3 74654-06-1
Price
US $0.00/g
Min. Order
5g
Purity
>98.00%
Supply Ability
5g
Release date
2024-03-23

74654-06-1, 1-azido-2-[2-(2-methoxyethoxy)ethoxy]ethaneRelated Search:


  • 1-azido-2-[2-(2-methoxyethoxy)ethoxy]ethane
  • mPEG3-Azide
  • N3-PEG3-O-ME
  • 2-(2-(2-methoxyethoxy)ethoxy)ethyl azide
  • azido-mPEG3
  • 1-Azido-3,6,9-trioxadecane
  • Ethane, 1-(2-azidoethoxy)-2-(2-methoxyethoxy)-
  • mPEG3-N3/Ethane, 1-(2-azidoethoxy)-2-(2-methoxyethoxy)-
  • 1-Azido-2-(2-(2-methoxyethoxy)ethoxy)ethane - [A73309]
  • 74654-06-1
  • peg