ChemicalBook > CAS DataBase List > 2-[2-(2-Azidoethoxy)ethoxy]ethanamine

2-[2-(2-Azidoethoxy)ethoxy]ethanamine

Product Name
2-[2-(2-Azidoethoxy)ethoxy]ethanamine
CAS No.
166388-57-4
Chemical Name
2-[2-(2-Azidoethoxy)ethoxy]ethanamine
Synonyms
N3-PEG2-NH2;Azido-PEG2-NH2;H2N-C2-PEG2-N3;Azide-PEG3-Amine;Azido-PEG2-Amine;N3-PEG2-CH2CH2NH2;Azido-PEG2-C2-amine;Azido-PEG2-CH2CH2NH2;Azido-PEG2-CH2CH2-Amine;Amino-PEG2-azide,NH2-PEG2-N3
CBNumber
CB02484811
Molecular Formula
C6H14N4O2
Formula Weight
174.2
MOL File
166388-57-4.mol
More
Less

2-[2-(2-Azidoethoxy)ethoxy]ethanamine Property

solubility 
Soluble in Water, DMSO, DMF, DCM
form 
Liquid
color 
Colorless to light yellow
CAS DataBase Reference
166388-57-4
More
Less

Safety

HS Code 
2929900090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More
Less

N-Bromosuccinimide Price

TRC
Product number
B407568
Product name
2-[2-(2-Azidoethoxy)ethoxy]ethanamine
Packaging
1g
Price
$185
Updated
2021/12/16
Biosynth Carbosynth
Product number
FP73033
Product name
Azido-PEG2-amine
Packaging
1g
Price
$200
Updated
2021/12/16
BroadPharm
Product number
BP-20692
Product name
Azido-PEG2-amine
Purity
98%
Packaging
5G
Price
$295
Updated
2021/12/16
Biosynth Carbosynth
Product number
FP73033
Product name
Azido-PEG2-amine
Packaging
2g
Price
$300
Updated
2021/12/16
ChemScene
Product number
CS-0114352
Product name
Azido-PEG2-C2-amine
Packaging
5g
Price
$395
Updated
2021/12/16
More
Less

2-[2-(2-Azidoethoxy)ethoxy]ethanamine Chemical Properties,Usage,Production

Description

Azido-PEG2-amine is a bifunctional crosslinker containing an amino and an azide group. The amino group is reactive with carboxylic acids, activated NHS esters,. The azide(N3) group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.

Synthesis

2-[2-(2-Hydroxyethoxy)ethoxy]ethyl chloride (15 g, 88.9 mmol), NaI(4.06 g, 27.1 mmol), and NaN3 (45.3 mg, 697 mmol) were dissolved in distilled water (90 mL), and the solution was stirred for 48 h at 50 °C. The reaction mixture extracted with ethyl acetate for three times. The organic layer was dried over Na2SO4 , and evaporated to collect 2-[2-(2-azidoethoxy)ethoxy]ethanol (14.0 g, 90.1%) as a yellow oil.To the solution 2-[2-(2-azidoethoxy)ethoxy]ethanol (8 g, 45.7 mmol) in THF (22.4 mL), 6 M NaOH(20.8 mL) and TsCl (13.1 g, 68.6 mmol) were added at 0 °C. The reaction mixture was stirred for 1 h at room temperature under nitrogen atmosphere. The solution was then extracted with diethyl ether four times, and the organic layer was washed with 1 M NaOH. After evaporation of the organic layer,2-[2-(2-azidoethoxy)ethoxy]ethyl tosylate (16.8 g, 98.6%) was obtained as a yellow oil.Finally, ammonia solution (28%, 14.8 mL, 365 mol) was added to the 2-[2-(2-azidoethoxy)ethoxy]-ethyl tosylate (8 g, 24.3 mmol) dissolved in THF (95.9 mL), and reaction mixture was stirred for 96 h at 40 °C. After the reaction, distilled water (50 mL) was added to the solution. The mixture was washed with diethyl ether and then extracted with dichloromethane. The organic layer was dried over NaSO4 and evaporated to obtain 2-[2-(2-azidoethoxy)ethoxy]ethanamine (2.49 g, 58.8%) as a yellow oil.

2-[2-(2-Azidoethoxy)ethoxy]ethanamine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2-[2-(2-Azidoethoxy)ethoxy]ethanamine Suppliers

China 96 India 3 South Korea 1 United Kingdom 2 United States 8 Global 110
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
Tel
0431-80514535 19917294565
Email
caoy@chemextension.com
Country
China
ProdList
4753
Advantage
58
PharmaBlock Sciences (Nanjing),Inc.
Tel
025-86918202 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
4986
Advantage
55
Alabiochem Tech.Co., Ltd.
Tel
512-58900862 400-0707518
Fax
0086-512-56765862
Email
sales@alabiochem.com
Country
China
ProdList
967
Advantage
59
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9513
Advantage
66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
Daicel Chiral Technologies (China)CO.,LTD
Tel
021-50460086-9 15921403865
Fax
+86-21-50462321
Email
han_yajun@dctc.daicel.com
Country
China
ProdList
7195
Advantage
65
ChemPep, Inc.
Tel
+1 (888) 615-9178 / (561) 791-8787
Fax
+1 (561) 791-8728
Email
service@chempep.com
Country
United States
ProdList
2138
Advantage
57
Chengdu Pukang Biotechnology Co., Ltd
Tel
028-82550498 19102685862
Fax
086-28-82550468
Email
sales@pu-kang.com
Country
China
ProdList
485
Advantage
58
More
Less

View Lastest Price from 2-[2-(2-Azidoethoxy)ethoxy]ethanamine manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
azido-PEG2-amine 166388-57-4
Price
US $0.00/g
Min. Order
10g
Purity
>98.00%
Supply Ability
10g
Release date
2024-03-23

166388-57-4, 2-[2-(2-Azidoethoxy)ethoxy]ethanamineRelated Search:

2-(2-Azidoethoxy)ethanol Biotin-PEG3-propionic acid HS-PEG4-tBu 5,8,11,14-Tetraoxa-2-azahexadecanoic acid,16-amino-,1,1-dimethyl ester 3,6,9,12-tetraoxatridecylamine PENTAETHYLENE GLYCOL H2N-PEG4-tBu 1H-Thieno[3,4-d]imidazole-4-pentanamide,N-(14-amino-3,6,9,12-tetraoxatetradec-1-yl)hexahydro-2-oxo-,(3aS,4S,6aR)- Decaethylene glycol O-(2-AMINOETHYL)-O-(2-(BOC-AMINO)ETHYL)OCTAETHYLENE GLYCOL 6-Maleimidocaproic acid 2-[2-(2-methoxyethoxy)ethoxy]-ethanethiol 2,5,8,11,14,17,20,23-Octaoxapentacosane-25-thiol HEPTAETHYLENE GLYCOL FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID MPEG7-CH2CH2COOH (R)-N-(3,6,9,12-Tetraoxatridecyl)-alpha-lipoamide Z-15-aMino-4,7,10,13-tetraoxapentadecacanoic acid

  • N3-PEG2-CH2CH2NH2
  • Azido-PEG2-Amine
  • 2-[2-(2-Azidoethoxy)ethoxy]ethanamine
  • N3-PEG2-NH2
  • Azido-PEG2-NH2
  • 2-[2-(2-Azido-ethoxy)-ethoxy]-ethylamine
  • Azido-PEG2-C2-amine
  • Amino-PEG2-azide,NH2-PEG2-N3
  • Azide-PEG3-Amine
  • Ethanamine, 2-[2-(2-azidoethoxy)ethoxy]-
  • N3-PEG2-CH2CH2NH2/Ethanamine, 2-[2-(2-azidoethoxy)ethoxy]-
  • H2N-C2-PEG2-N3
  • Azido-PEG2-CH2CH2NH2
  • Azido-PEG2-CH2CH2-Amine
  • 166388-57-4
  • 1660388-57-4
  • peg