2-(2-Azidoethoxy)ethanol
- Product Name
- 2-(2-Azidoethoxy)ethanol
- CAS No.
- 139115-90-5
- Chemical Name
- 2-(2-Azidoethoxy)ethanol
- Synonyms
- 2-(2-azidoethoxy)ethan-1-ol;Azido-PEG2;N3-PEG2-OH;Azido - PEG1;Azido-PEG2-OH;Azido-PEG2-Alchol;Azido-PEG2-alcohol;AZIDO-PEG2-HYDROXY;2-(2-Azidoethoxy)ethanol;Azide polyethylene glycol
- CBNumber
- CB03036228
- Molecular Formula
- C4H9N3O2
- Formula Weight
- 131.14
- MOL File
- 139115-90-5.mol
2-(2-Azidoethoxy)ethanol Property
- storage temp.
- Storage temp. 2-8°C
- form
- liquid
- color
- Yellowish
- InChI
- InChI=1S/C4H9N3O2/c5-7-6-1-3-9-4-2-8/h8H,1-4H2
- InChIKey
- CGJFKQFYZOARRV-UHFFFAOYSA-N
- SMILES
- C(OCCO)CN=[N+]=[N-]
- CAS DataBase Reference
- 139115-90-5
Safety
- HS Code
- 2929900090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
N-Bromosuccinimide Price
- Product number
- A3701
- Product name
- 2-(2-Azidoethoxy)ethan-1-ol
- Purity
- min. 95.0 %
- Packaging
- 250MG
- Price
- $153
- Updated
- 2025/07/31
- Product number
- A965635
- Product name
- Azido-PEG2-alcohol
- Packaging
- 50mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- BP-20714
- Product name
- Azido-PEG2-alcohol
- Purity
- 98%
- Packaging
- 100mg
- Price
- $120
- Updated
- 2021/12/16
- Product number
- AMTGC484
- Product name
- Azido-PEG2-alcohol
- Packaging
- 5g
- Price
- $210
- Updated
- 2021/12/16
- Product number
- BP-20714
- Product name
- Azido-PEG2-alcohol
- Purity
- 98%
- Packaging
- 250mg
- Price
- $230
- Updated
- 2021/12/16
2-(2-Azidoethoxy)ethanol Chemical Properties,Usage,Production
Description
Azido-PEG2-alcohol is a PEG linker containing an azide group and a terminal hydroxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
Uses
Azido-PEG2-alcohol can be used for biosensing applications.
Synthesis
Add 50g of diethylene glycol and 34g of triethylamine to 500ml of dichloromethane with stirring, weigh 54g of p-toluenesulfonyl chloride dissolved in 150ml of dichloromethane, and then add it dropwise to the reaction system under the condition of ice-water bath, and after dropping, the reaction will take place at 20?? for 12h. The TLC shows the end of the reaction, and then add 400ml of water to wash, separate the liquid, dry the organic phase with anhydrous sodium sulfate, spin dry and then purify 55g of intermediate A through column chromatography. The organic phase was dried with anhydrous sodium sulfate and spun dry, and then purified by column chromatography to obtain 55g of Intermediate A, yield: 90%. The NMR data were as follows: 1HNMR (400MHz, CDCl3): δ: 7.792 (d, J=8.4Hz, 2H); 7.350 (d, J=8.4Hz, 2H); 4.158 (t, J=4.4Hz, 2H); 3.702~3.567 (m, 6H); 2.818 (s, 1H); 2.435 (s, 3H).
IC 50
PEGs
2-(2-Azidoethoxy)ethanol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-(2-Azidoethoxy)ethanol manufacturers
- Product
- azido-PEG2-OH 139115-90-5
- Price
- US $0.00/g
- Min. Order
- 10g
- Purity
- >98.00%
- Supply Ability
- 10g
- Release date
- 2024-03-23