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Diethyl fumarate

Product Name
Diethyl fumarate
CAS No.
623-91-6
Chemical Name
Diethyl fumarate
Synonyms
ETHYL FUMARATE;Diethyl fuMara;iethylfumarate;Diethyl fuMarat;DIETHYL FUMARATE;Diethyl fumalate;Anti-Psoriaticum;diethyl furmarate;DiethylFumarate>RARECHEM AL BI 1505
CBNumber
CB6220839
Molecular Formula
C8H12O4
Formula Weight
172.18
MOL File
623-91-6.mol
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Diethyl fumarate Property

Melting point:
1-2 °C (lit.)
Boiling point:
218-219 °C (lit.)
Density 
1.052 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.44(lit.)
Flash point:
197 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
3.1g/l
form 
Liquid
color 
Clear colorless to slightly yellow
Water Solubility 
immiscible
BRN 
775347
Dielectric constant
6.5(23℃)
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents, acids, bases, reducing agents.
InChIKey
IEPRKVQEAMIZSS-AATRIKPKSA-N
LogP
2.200 (est)
CAS DataBase Reference
623-91-6(CAS DataBase Reference)
NIST Chemistry Reference
2-Butenedioic acid (E)-, diethyl ester(623-91-6)
EPA Substance Registry System
Diethyl fumarate (623-91-6)
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Safety

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
23-24/25
RIDADR 
NA 1993 / PGIII
WGK Germany 
3
RTECS 
EM5950000
TSCA 
Yes
HS Code 
29171990
Hazardous Substances Data
623-91-6(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H227Combustible liquid

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P403+P235Store in a well-ventilated place. Keep cool.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D95654
Product name
Diethyl fumarate
Purity
98%
Packaging
5g
Price
$107
Updated
2024/03/01
Sigma-Aldrich
Product number
D95654
Product name
Diethyl fumarate
Purity
98%
Packaging
100g
Price
$131
Updated
2024/03/01
TCI Chemical
Product number
F0068
Product name
Diethyl Fumarate
Purity
>98.0%(GC)
Packaging
25mL
Price
$20
Updated
2024/03/01
TCI Chemical
Product number
F0068
Product name
Diethyl Fumarate
Purity
>98.0%(GC)
Packaging
500mL
Price
$88
Updated
2024/03/01
Alfa Aesar
Product number
A16214
Product name
Diethyl fumarate, 98%
Packaging
100g
Price
$37.3
Updated
2023/06/20
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Diethyl fumarate Chemical Properties,Usage,Production

Chemical Properties

colourless liquid

Uses

It is used as a pesticide or comonomer for the production of polystyrene.

Uses

Diethyl fumarate is unsaturated polyester resins are used in applications, such as reinforced glass fiber for boats, piping, bathtubs, roof panels, etc., and as protective coatings, finishes, and lacquers.

Uses

Diethyl Fumarate is a reagent in the preparation of chiral hydroisoindolines via Diels-Alder cycloaddition which are potent, brain-penetrant, human neurokinin-1 receptor antagonists.

Production Methods

Diethyl fumarate is manufactured via esterification of ethanol with fumaric acid.

Definition

ChEBI: A dieter obtained by the formal condensation of fumaric acid with ethanol.

Synthesis Reference(s)

The Journal of Organic Chemistry, 52, p. 323, 1987 DOI: 10.1021/jo00378a045
Tetrahedron Letters, 28, p. 6649, 1987 DOI: 10.1016/S0040-4039(00)96936-3

Purification Methods

Wash the fumarate with aqueous 5% Na2CO3, then with saturated CaCl2 solution, dry with CaCl2 and distil it. [Beilstein 2 IV 2207.]

Diethyl fumarate Preparation Products And Raw materials

Raw materials

Preparation Products

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Diethyl fumarate Suppliers

Changzhou Xiaobu Fine Chemicals Co., Ltd
Tel
0512-66388446 15851926283
Email
42050065@qq.com
Country
China
ProdList
62
Advantage
58
Wuhan EnTai Technology Development Co,.Ltd
Tel
86-27-82330560
Fax
86-27-82330547
Email
2536851935@qq.com
Country
China
ProdList
348
Advantage
69
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1998
Advantage
65
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Ark Pharm, Inc.
Tel
847-367-3680
Fax
847-367-3681
Email
sales@arkpharminc.com
Country
United States
ProdList
1670
Advantage
56
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057 18501085097
Fax
010-89508210
Email
sales3.gd@hwrkchemical.com
Country
China
ProdList
7583
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
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View Lastest Price from Diethyl fumarate manufacturers

Hebei Saisier Technology Co., LTD
Product
Diethyl fumarate 623-91-6
Price
US $6.00/KG
Min. Order
1KG
Purity
More than 99%
Supply Ability
2000KG/Month
Release date
2024-04-03
Hebei Saisier Technology Co., LTD
Product
Diethyl fumarate 623-91-6
Price
US $6.00/KG
Min. Order
1KG
Purity
More than 99%
Supply Ability
2000KG/Month
Release date
2024-04-10
Henan Fengda Chemical Co., Ltd
Product
Diethyl fumarate 623-91-6
Price
US $8.00-0.80/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-22

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