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DIETHYL PHOSPHATE

Product Name
DIETHYL PHOSPHATE
CAS No.
598-02-7
Chemical Name
DIETHYL PHOSPHATE
Synonyms
DIETHYL HYDROGEN PHOSPHATE;IETHYLPHOSPHATE;di-ethylphosphat;DIETHYL PHOSPHATE;ETHYLACIDPHOSPHATE;diethylacidphosphate;O,O-DIETHYLPHOSPHATE;diethylphosphoricacid;Diethyl phosphate,98%;Diethyl acid phosphate
CBNumber
CB7331426
Molecular Formula
C4H11O4P
Formula Weight
154.1
MOL File
598-02-7.mol
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DIETHYL PHOSPHATE Property

Melting point:
6 °C
Boiling point:
203 °C
Density 
1.29
refractive index 
1.4170
Flash point:
91 °C
storage temp. 
Sealed in dry,2-8°C
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka
1.42±0.50(Predicted)
form 
Liquid
color 
Clear colorless to light yellow-orange
Stability:
Moisture Sensitive
InChI
InChI=1S/C4H11O4P/c1-3-7-9(5,6)8-4-2/h3-4H2,1-2H3,(H,5,6)
InChIKey
UCQFCFPECQILOL-UHFFFAOYSA-N
SMILES
P(O)(OCC)(OCC)=O
EPA Substance Registry System
Phosphoric acid, diethyl ester (598-02-7)
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Safety

Hazard Codes 
Xi,T,F
Risk Statements 
36/37/38-39/23/24/25-23/24/25-11
Safety Statements 
37/39-26-36-45-36/37-16-7
RTECS 
TC0665000
HS Code 
29199000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H335May cause respiratory irritation

H372Causes damage to organs through prolonged or repeated exposure

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
P359430
Product name
PhosphoricAcidDiethylEster
Packaging
500mg
Price
$215
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD74763
Product name
Diethyl Phosphate
Packaging
1g
Price
$70
Updated
2021/12/16
AK Scientific
Product number
8907AB
Product name
Diethylhydrogenphosphate
Packaging
1g
Price
$79
Updated
2021/12/16
Matrix Scientific
Product number
098586
Product name
Diethyl hydrogen phosphate
Purity
95+%
Packaging
1g
Price
$105
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD74763
Product name
Diethyl Phosphate
Packaging
2g
Price
$120
Updated
2021/12/16
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DIETHYL PHOSPHATE Chemical Properties,Usage,Production

Chemical Properties

clear colorless to light yellow-orange liquid

Uses

Phosphoric acid diethyl ester is an organophosphate that is usually found in pesticides and is known to induce changes in male hormone profile by decreasing serum testosterone and inhibin B levels. Phosphoric acid diethyl ester is also known to negatively affect the health of women and newborns living in agricultural communities.

Definition

ChEBI: A dialkyl phosphate having ethyl as the alkyl group.

Synthesis Reference(s)

The Journal of Organic Chemistry, 28, p. 2089, 1963 DOI: 10.1021/jo01043a035
Tetrahedron Letters, 29, p. 619, 1988 DOI: 10.1016/S0040-4039(00)80165-3

in vivo

Diethyl phosphate (oral gavage; 0.08-0.8 mg/kg; 24 weeks) can lead to the disturbance of endocrine hormones and related metabolic indexes in rats[1].
Diethyl phosphate (oral gavage; 0.08-0.13 mg/kg; 20 weeks) affects the intestinal microbiota, serum hormones and pro-inflammatory cytokines[2].

Animal Model:Adult male Wistar rats aged 7-8 weeks old (344.4 ± 21.0 g)[1]
Dosage:0.08 or 0.8 mg/kg
Administration:Oral gavage (i.g.); 24 weeks
Result:Did not affect the body weight of rats and food intake.
Significantly decreased serum levels of TC, TG and LDL-C in rats.
Resulted in a decrease in sperm concentration, while the sperm abnormality rate increased, did not affect the sperm morphology in rats.
Increased the serum levels of FSH and estradiol, while the serum levels of LH and testosterone decreased.
Could cause thyroid-related hormone disorders in the serum of rats, causing symptoms of hyperthyroidism in rats, and could also lead to abnormal expression of thyroid hormone-related genes in the rat liver.
Animal Model:Male Wistar rats aged 7 weeks old[2]
Dosage:0.08 or 0.13 mg/kg
Administration:Oral gavage (i.g.); 20 weeks
Result:Significantly enriched opportunistic pathogens, including Paraprevotella, Parabacteroides, Alloprevotella, and Helicobacter, leading to a decrease in IL-6.
Enriched the butyrate-producing genera, Alloprevotella and Intestinimonas, leading to an increase in estradiol and a resulting decrease in total triglycerides (TGs) and low-density lipoprotein cholesterol (LDL-C) in high dose group.
Induced increases in peptide tyrosine-tyrosine (PYY) and ghrelin.

DIETHYL PHOSPHATE Preparation Products And Raw materials

Raw materials

Diethyl phosphite

Preparation Products

Diethyl cyanophosphonate
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DIETHYL PHOSPHATE Suppliers

Belgium 2 China 129 France 1 Germany 5 India 3 Japan 2 Switzerland 2 United Kingdom 6 United States 23 Global 173
Shanghai Brain Biotechnology Co., Ltd.
Tel
13564638271
Fax
021-68948280
Email
shhjiang1977@163.com
Country
China
ProdList
2987
Advantage
55
Nanjing Easichem Co. ltd.
Tel
18061688856
Email
easichem@126.com
Country
China
ProdList
477
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Beijing HwrkChemical Technology Co., Ltd
Tel
18515581800 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
9400
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9310
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
Advantage
64
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9883
Advantage
59
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View Lastest Price from DIETHYL PHOSPHATE manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
DIETHYL PHOSPHATE 598-02-7
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2025-02-28
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
Product
Diethyl Phosphate 598-02-7
Price
US $0.00/g
Min. Order
1g
Purity
More Than 99%
Supply Ability
100kg/Month
Release date
2024-11-15
Shaanxi Dideu Medichem Co. Ltd
Product
Diethylphosphate 598-02-7
Price
US $1.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20000KG
Release date
2020-01-09

598-02-7, DIETHYL PHOSPHATERelated Search:

Dibenzyl phosphate Potassium di-tert-butyl phosphate DI-TERT-BUTYLPHOSPHATE, TETRABUTYLAMMONIUM SALT Trimethyl phosphate Potassium Phosphate Dibasic Potassium Phosphate Monobasic Ammonium dihydrogen phosphate Sodium phosphate monobasic Potassium phosphate tribasic Manganous dihydrogen phosphate Hydroxyapatite Tri-o-cresyl Phosphate Diphenyl phosphate Triisobutyl phosphate Triphenyl phosphate TRIPROPYL PHOSPHATE Tributyl phosphate TRIALLYL PHOSPHATE

  • diethylacidphosphate
  • di-ethylphosphat
  • diethylphosphoricacid
  • Ethyl phosphate, (ETO)2(HO)PO
  • o,o-diethylhydrogenphosphate
  • Phosphoricacid,diethylester
  • DIETHYL PHOSPHATE
  • DIETHYL HYDROGEN PHOSPHATE
  • ETHYLACIDPHOSPHATE
  • DIETHYL PHOSPHATE, 100MG, NEAT
  • Diethyl phosphate, tech., balance phosphoric acid, 75%
  • Diethyl phosphate (mono- & di-)
  • O,O-DIETHYLPHOSPHATE
  • Diethyl hydrogen phosphate solution
  • IETHYLPHOSPHATE
  • Diethyl phosphate, tech., 75%
  • Diethyl acid phosphate
  • Diethyl phosphoric acid
  • Phosphoric acid diethyl
  • Phosphoric acid hydrogen diethyl ester
  • Diethyl phosphate,98%
  • Diethyl phosphate,75%,tech., balance phosphoric acid
  • Diethyl phosphate, 75%, balance phosphoric acid, tech.
  • Diethyl phosphate (mono &amp
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  • Diethylphosphate @100 μg/mL in MeOH
  • Chlorpyrifos Impurity 3 (Diethyl Phosphate)
  • Diethylhydrogenphosphat
  • Chlorpyrifos Impurity 5 (Diethyl Phosphate)
  • iethylhydrogenphosphate
  • TIANFUCHEM--598-02-7--High purity DIETHYL PHOSPHATE factory price
  • O,O-Diethyl hydrogenphosphate in methanol
  • Clopyrithion Impurity 4
  • Impurity C-3 (diethyl phosphate)
  • Diethyl phosphate, 10 mM in DMSO
  • 598-02-7
  • C2H5O2POOH
  • C4H11O4P
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  • Metabolites
  • Pesticides&Metabolites