ChemicalBook > CAS DataBase List > DIETHYL PHOSPHATE

DIETHYL PHOSPHATE

Product Name: DIETHYL PHOSPHATE
CAS No.: 598-02-7
Chemical Name: DIETHYL PHOSPHATE
Synonyms: DIETHYL HYDROGEN PHOSPHATE;IETHYLPHOSPHATE;di-ethylphosphat;DIETHYL PHOSPHATE;ETHYLACIDPHOSPHATE;diethylacidphosphate;O,O-DIETHYLPHOSPHATE;diethylphosphoricacid;Diethyl phosphate,98%;Diethyl acid phosphate
CBNumber: CB7331426
Molecular Formula: C4H11O4P
Formula Weight: 154.1
MOL File: 598-02-7.mol

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DIETHYL PHOSPHATE Property

Melting point:: 6 °C
Boiling point:: 203 °C
Density: 1.29
refractive index: 1.4170
Flash point:: 91 °C
storage temp.: Sealed in dry,2-8°C
solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka: 1.42±0.50(Predicted)
form: Liquid
color: Clear colorless to light yellow-orange
Stability:: Moisture Sensitive
InChI: InChI=1S/C4H11O4P/c1-3-7-9(5,6)8-4-2/h3-4H2,1-2H3,(H,5,6)
InChIKey: UCQFCFPECQILOL-UHFFFAOYSA-N
SMILES: P(O)(OCC)(OCC)=O
EPA Substance Registry System: Phosphoric acid, diethyl ester (598-02-7)

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Safety

Hazard Codes: Xi,T,F
Risk Statements: 36/37/38-39/23/24/25-23/24/25-11
Safety Statements: 37/39-26-36-45-36/37-16-7
RTECS: TC0665000
HS Code: 29199000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H335May cause respiratory irritation

H372Causes damage to organs through prolonged or repeated exposure

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: P359430
Product name: PhosphoricAcidDiethylEster
Packaging: 500mg
Price: $215
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD74763
Product name: Diethyl Phosphate
Packaging: 5G
Price: $250
Updated: 2021/12/16

Matrix Scientific

Product number: 098586
Product name: Diethyl hydrogen phosphate
Purity: 95+%
Packaging: 5g
Price: $345
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD74763
Product name: Diethyl Phosphate
Packaging: 10g
Price: $400
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 72018
Product name: PhosphoricAcidDiethylEster
Packaging: 100mg
Price: $610
Updated: 2021/12/16

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DIETHYL PHOSPHATE Chemical Properties,Usage,Production

Chemical Properties

clear colorless to light yellow-orange liquid

Uses

Phosphoric acid diethyl ester is an organophosphate that is usually found in pesticides and is known to induce changes in male hormone profile by decreasing serum testosterone and inhibin B levels. Phosphoric acid diethyl ester is also known to negatively affect the health of women and newborns living in agricultural communities.

Definition

ChEBI: A dialkyl phosphate having ethyl as the alkyl group.

Synthesis Reference(s)

The Journal of Organic Chemistry, 28, p. 2089, 1963 DOI: 10.1021/jo01043a035
Tetrahedron Letters, 29, p. 619, 1988 DOI: 10.1016/S0040-4039(00)80165-3

in vivo

Diethyl phosphate (oral gavage; 0.08-0.8 mg/kg; 24 weeks) can lead to the disturbance of endocrine hormones and related metabolic indexes in rats^[1].
Diethyl phosphate (oral gavage; 0.08-0.13 mg/kg; 20 weeks) affects the intestinal microbiota, serum hormones and pro-inflammatory cytokines^[2].

Animal Model:	Adult male Wistar rats aged 7-8 weeks old (344.4 ± 21.0 g)^[1]
Dosage:	0.08 or 0.8 mg/kg
Administration:	Oral gavage (i.g.); 24 weeks
Result:	Did not affect the body weight of rats and food intake. Significantly decreased serum levels of TC, TG and LDL-C in rats. Resulted in a decrease in sperm concentration, while the sperm abnormality rate increased, did not affect the sperm morphology in rats. Increased the serum levels of FSH and estradiol, while the serum levels of LH and testosterone decreased. Could cause thyroid-related hormone disorders in the serum of rats, causing symptoms of hyperthyroidism in rats, and could also lead to abnormal expression of thyroid hormone-related genes in the rat liver.

Animal Model:	Male Wistar rats aged 7 weeks old^[2]
Dosage:	0.08 or 0.13 mg/kg
Administration:	Oral gavage (i.g.); 20 weeks
Result:	Significantly enriched opportunistic pathogens, including Paraprevotella, Parabacteroides, Alloprevotella, and Helicobacter, leading to a decrease in IL-6. Enriched the butyrate-producing genera, Alloprevotella and Intestinimonas, leading to an increase in estradiol and a resulting decrease in total triglycerides (TGs) and low-density lipoprotein cholesterol (LDL-C) in high dose group. Induced increases in peptide tyrosine-tyrosine (PYY) and ghrelin.

DIETHYL PHOSPHATE Preparation Products And Raw materials

Raw materials

Diethyl phosphite

Preparation Products

Diethyl cyanophosphonate

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View Lastest Price from DIETHYL PHOSPHATE manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: DIETHYL PHOSPHATE 598-02-7
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-02-28

BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.

Product: Diethyl Phosphate 598-02-7
Price: US $0.00/g
Min. Order: 1g
Purity: More Than 99%
Supply Ability: 100kg/Month
Release date: 2024-11-15

Shaanxi Dideu Medichem Co. Ltd

Product: Diethylphosphate 598-02-7
Price: US $1.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20000KG
Release date: 2020-01-09

598-02-7, DIETHYL PHOSPHATERelated Search:

Dibenzyl phosphate Potassium di-tert-butyl phosphate DI-TERT-BUTYLPHOSPHATE, TETRABUTYLAMMONIUM SALT Trimethyl phosphate Potassium Phosphate Dibasic Potassium Phosphate Monobasic Ammonium dihydrogen phosphate Sodium phosphate monobasic Potassium phosphate tribasic Manganous dihydrogen phosphate Hydroxyapatite Tri-o-cresyl Phosphate Diphenyl phosphate Triisobutyl phosphate Triphenyl phosphate TRIPROPYL PHOSPHATE Tributyl phosphate TRIALLYL PHOSPHATE

diethylacidphosphate

di-ethylphosphat

diethylphosphoricacid

Ethyl phosphate, (ETO)2(HO)PO

o,o-diethylhydrogenphosphate

Phosphoricacid,diethylester

DIETHYL PHOSPHATE

DIETHYL HYDROGEN PHOSPHATE

ETHYLACIDPHOSPHATE

DIETHYL PHOSPHATE, 100MG, NEAT

Diethyl phosphate, tech., balance phosphoric acid, 75%

Diethyl phosphate (mono- & di-)

O,O-DIETHYLPHOSPHATE

Diethyl hydrogen phosphate solution

IETHYLPHOSPHATE

Diethyl phosphate, tech., 75%

Diethyl acid phosphate

Diethyl phosphoric acid

Phosphoric acid diethyl

Phosphoric acid hydrogen diethyl ester

Diethyl phosphate,98%

Diethyl phosphate,75%,tech., balance phosphoric acid

Diethyl phosphate, 75%, balance phosphoric acid, tech.

Diethyl phosphate (mono &amp

di) @100 μg/mL in Toluene

Diethylphosphate @100 μg/mL in MeOH

Chlorpyrifos Impurity 3 (Diethyl Phosphate)

Diethylhydrogenphosphat

Chlorpyrifos Impurity 5 (Diethyl Phosphate)

iethylhydrogenphosphate

TIANFUCHEM--598-02-7--High purity DIETHYL PHOSPHATE factory price

O,O-Diethyl hydrogenphosphate in methanol

Clopyrithion Impurity 4

Impurity C-3 (diethyl phosphate)

Diethyl phosphate, 10 mM in DMSO

598-02-7

C2H5O2POOH

C4H11O4P

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