Chemical Properties Uses Preparation Potential Exposure
ChemicalBook > CAS DataBase List > Tributyl phosphate

Tributyl phosphate

Chemical Properties Uses Preparation Potential Exposure
Product Name
Tributyl phosphate
CAS No.
126-73-8
Chemical Name
Tributyl phosphate
Synonyms
TBP;TRI-N-BUTYL PHOSPHATE;tributyl;ANTIFOAM T;AURORA KA-1641;BUTYL PHOSPHATE;Tributylphosphat;mcs2495;Tributyle;celluphos4
CBNumber
CB4187323
Molecular Formula
C12H27O4P
Formula Weight
266.31
MOL File
126-73-8.mol
More
Less

Tributyl phosphate Property

Melting point:
-79 °C (lit.)
Boiling point:
180-183 °C/22 mmHg (lit.)
Density 
0.979 g/mL at 25 °C (lit.)
vapor density 
9.2 (vs air)
vapor pressure 
27 mm Hg ( 178 °C)
refractive index 
n20/D 1.424(lit.)
Flash point:
380 °F
storage temp. 
Store below +30°C.
solubility 
water: soluble1ml in 165ml water
form 
Liquid
color 
Clear
Odor
Odorless
Water Solubility 
0.6 g/100 mL
Merck 
14,9618
BRN 
1710584
Exposure limits
TLV-TWA 2.18 mg/m3 (0.2 ppm) (ACGIH), 5 mg/m3 (OSHA and NIOSH); IDLH 1300 mg/m3 (120 ppm) (NIOSH).
Dielectric constant
8.2899999999999991
Dielectric constant
6.5(20℃)
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents. May be water sensitive.
LogP
4 at 20℃
CAS DataBase Reference
126-73-8(CAS DataBase Reference)
NIST Chemistry Reference
Tri-n-butylphosphate(126-73-8)
EPA Substance Registry System
Tributyl phosphate (126-73-8)
More
Less

Safety

Hazard Codes 
Xn,F
Risk Statements 
22-38-40-62-48/20-36/37/38-11-20/22
Safety Statements 
36/37-46-45-36/37/39-16-53
RIDADR 
UN 1208 3/PG 2
WGK Germany 
2
RTECS 
TC7700000
Autoignition Temperature
770 °F
TSCA 
Yes
HS Code 
29190010
Hazardous Substances Data
126-73-8(Hazardous Substances Data)
Toxicity
LD50 orally in rats: 3.0 g/kg (Smyth, Carpenter)
IDLA
30 ppm
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H351Suspected of causing cancer

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P308+P313IF exposed or concerned: Get medical advice/attention.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
EHU026741
Product name
Tributyl phosphate
Purity
targeting human RP13-786C16.1
Packaging
20μG
Price
$220
Updated
2024/03/01
Sigma-Aldrich
Product number
EHU026741
Product name
Tributyl phosphate
Purity
targeting human RP13-786C16.1
Packaging
50μG
Price
$391
Updated
2024/03/01
Sigma-Aldrich
Product number
8.18604
Product name
Tributyl phosphate
Purity
for synthesis
Packaging
1L
Price
$53.3
Updated
2024/03/01
Sigma-Aldrich
Product number
8.18604
Product name
Tributyl phosphate
Purity
for synthesis
Packaging
500mL
Price
$58.1
Updated
2024/03/01
Sigma-Aldrich
Product number
8.18604
Product name
Tributyl phosphate
Purity
for synthesis
Packaging
2.5L
Price
$288
Updated
2024/03/01
More
Less

Tributyl phosphate Chemical Properties,Usage,Production

Chemical Properties

Tributyl phosphate (126-73-8);is an odorless colorless to yellow liquid. The solubility of TBP is only 280 mg/L in water at 25°C. It is soluble in diethyl ether, benzene, carbon disulfide. It can be miscible with ethanol. It is stable, but it is incompatible with strong oxidizing agents.

Tributyl phosphate (TBP) is an organophosphorus compound widely used as a solvent in nuclear fuel reprocessing for the extraction of uranium and plutonium from other radionuclides.
The major uses of tributyl phosphate (TBP) in industry are as a flame retardant component of aircraft hydraulic fluid and as a solvent for rare earth extraction and purification. Minor uses of TBP include use as a defoamer additive in cement casings for oil wells, as an anti-air entrainment additive for coatings and floor finishes, as a solvent in nuclear fuel processing, and as a carrier for fluorescent dyes.
The microbial degradation of tributyl phosphate was carried out using Klebsiella pneumoniae S3 isolated from the soil. The solubilization behavior of TBP in aqueous solutions of L64-Pluronics was studied using light and small angle neutron scattering (SANS).

Uses

Tributyl phosphate (TBP,126-73-8) is a trialkyl phosphate that is the tributyl ester of phosphoric acid. TBP is a toxic organophosphorous compound widely used in many industrial applications, including significant usage in nuclear processing. TBP is a solvent and plasticizer for cellulose esters such as nitrocellulose and cellulose acetate. The major uses of TBP in industry are as a component of aircraft hydraulic fluid and as a solvent for extraction and purification of rare earth metals from their ores, such as uranium and plutonium. TBP is used also in mercerizing liquids, where it improves their wetting properties. TBP is also used as a heat exchange medium. TBP is used in some consumer products such as herbicides and water thinned paints and tinting bases.

Preparation

Tributyl phosphate(126-73-8) is manufactured by reaction of phosphoryl chloride with n-butanol.
A 1-liter four-necked flask is fitted with an efficient condenser, an air-tight stirrer, a short-stemmed dropping funnel and a thermometer. Calcium chloride tubes are attached to the top of dropping funnel and the reflux condenser. 137 ml (111 g) of dry n-butyl alcohol, 132.5 ml (130 g) of dry pyridine and 140 ml of dry benzene are placed in the flask, which is stirred and cooled in an ice-salt mixture until the temperature falls to – 5° C. 40.5 ml (76.5 g) of freshly redistilled (b.p. 106-107° C) phosphorus oxychloride are dropwise added from the funnel at such a rate that the temperature does not rise above 10° C. When all phosphorus oxychloride has been added the reaction mixture is gently refluxed for 2 hours and cooled to room temperature. 250 ml of water are added in order to dissolve the pyridine hydrochloride, the benzene layer is separated, washed several times with water until the washings are neutral, and dried over anhydrous sodium or magnesium sulfate. The benzene is removed by evaporation and crude tributyl phosphate is purified by distillation in a vacuum. The fraction boiling at 160-162°/15 mm or 138-140°/6 mm is collected yielding 95 g of pure tributyl phosphate.

Potential Exposure

The industrial application of this chemical is responsible for occupational exposure and environmental pollution. Exposure to TBP can be from ingestion, inhalation, or skin or eye contact. This exposure will most often happen from occupational use of hydraulic fluid. If TBP is released to the environment, it will bind tightly to dust particles in the air. Unbound TBP will break down in air. It will move slowly through soil because it will bind with soil particles. It may volatilize slowly from moist soil and water surfaces. It may build up in aquatic organisms. It will be broken down in water by microbes.

Description

On decomposition, TBP releases COx, toxic fumes of phosphoric acid, phosphorus oxides, and/or phosphine. TBP is incompatible with strong oxidising agents and alkalis. The major uses of TBP in industry are as a component of aircraft hydraulic fluid and as a solvent for rare earth extraction and purification. Minor uses of TBP include use as a defoamer additive in cement casings for oil wells, an anti-air entrainment additive for coatings and floor finishes, as well as a carrier for fluorescent dyes. The major uses of TBP comprise over 80% of the volume produced.

Chemical Properties

Stable, colorless liquid; odorless. Miscible with most solvents and diluents; soluble in water. Combustible.

Physical properties

Clear, colorless to pale yellow, odorless, slightly flammable, oily liquid

Uses

Tributyl phosphate is used as a plasticizer for cellulose esters, vinyl resins, and lacquers; and in making fireretardants, biocides, defoamers, and catalysts.

Uses

Tributyl phosphate is used as an antifoaming agent; plasticizer for cellulose esters, lacquers, plastic, and vinyl resins; component in hydraulic fluids for aircraft control systems.

Uses

Plasticizer for cellulose esters, lacquers, plastics, and vinyl resins.

Production Methods

Prepared by the reaction of phosphorus oxychloride with butyl alcohol.

Definition

ChEBI: A trialkyl phosphate that is the tributyl ester of phosphoric acid.

General Description

Tributyl phosphate is an organophosphorus compound, which is widely used as a flame retardant and plasticizer in a variety of industrial products.

Air & Water Reactions

Water insoluble. Reacts slowly with water under basic conditions.

Reactivity Profile

Tributyl phosphate is incompatible with strong oxidizing agents and strong bases. Attacks some forms of plastics and rubber .

Health Hazard

Tributyl phosphate is a neurotoxic compound and an irritant. The toxic effects are characteristic of organic phosphates. It inhibits cholinesterase activity and causes paralysis. Inaddition,itcancausedepressionofthecentralnervoussystem,aswellasirritationofthe skin,eyes,andrespiratorypassage.Inhalation toxicity data in the literature are inconsistent.
The oral toxicity in rats was low; the LD50 value was reported as 1189 mg/kg (NIOSH 1986).
The pure liquid instilled into rabbits’ eyes caused severe irritation but no permanent damage. The irritation effect on the skin is mild.
Tributyl phosphate exhibited teratogenic effects in rats. There is no report on its carcinogenicity..

Fire Hazard

Special Hazards of Combustion Products: Toxic fumes of PO x

Industrial uses

1. As an antifoaming agent.
2. As a plasticizer for cellulose esters, lacquers, plastics, and vinyl resins.
3. As a complexing agent in the extraction of heavy metals, especially for the extraction of metal ions from solutions of reactor products in nuclear fuel reprocessing.
4. As an aircraft hydraulic fluid.
5. As a heat exchange medium and dielectric.
6. As a pigment-grinding agent.

Safety Profile

Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion, inhalation, and subcutaneous routes. Experimental reproductive effects. A skin, eye, and mucous membrane irritant. Combustible when exposed to heat or flame. To fight fire, use CO2, dry chemical, fog, mist. When heated to decomposition it emits toxic fumes of POx.

Carcinogenicity

TBP was not genotoxic in a variety of in vivo and in vitro assays.7 It has been suggested that the carcinogenic effects of TBP are species- and organ specific. The necrotic actions of TBP (or a metabolite) on rat urinary bladder epithelium may induce chronic repair processes that cause the normal epithelium to be transformed into its metaplastic and neoplastic forms.
TBP was not teratogenic when administered to rats and rabbits during gestation; fetotoxic effects (delayed ossification and reduced fetal body weights) occurred in rats at doses that caused severe maternal toxicity. There was no evidence of reproductive toxicity or reproductive organ pathology in twogeneration studies in rats fed TBP in the diet.

Environmental Fate

Biological. Indigenous microbes in Mississippi River water degraded tributyl phosphate to carbon dioxide. After 4 wk, 90.8% of the theoretical carbon dioxide had evolved (Saeger et al., 1979).
Chemical/Physical. Complete hydrolysis yields 1-butanol and phosphoric acid via the intermediates dibutyl phosphate and monobutyl phosphate (Thomas and Macaskie, 1996).

Purification Methods

The main contaminants in commercial samples are organic pyrophosphates, monoand dibutyl phosphates and butanol. It is purified by washing successively with 0.2M HNO3 (three times), 0.2M NaOH (three times) and water (three times), then fractionally distilled under vacuum. [Yoshida J Inorg Nucl Chem 24 1257 1962.] It has also been purified via its uranyl nitrate addition compound, obtained by saturating the crude phosphate with uranyl nitrate. This compound is crystallised three times from n-hexane by cooling to -40o, and then decomposed by washing with Na2CO3 and water. Hexane is removed by steam distillation; the water is then evaporated under reduced pressure, and the residue is distilled under reduced pressure. [Siddall & Dukes J Am Chem Soc 81 790 1959.] Alternatively, wash it with water, then with 1% NaOH or 5% Na2CO3 for several hours, then finally with water. Dry it under reduced pressure and fractionate it carefully under vacuum. It is a stable colourless oil, sparingly soluble in H2O (1mL dissolves in 165mL of H2O), but freely miscible in organic solvents. [Kuivila & Masterton J Am Chem Soc 74 4953 1952, Cox & Westheimer J Am Chem Soc 80 5441 1958, 31P NMR: Van Wazer J Am Chem Soc 78 5715 1956, Fertig et al. J Chem Soc 1488 1957, Beilstein 1 IV 1531.]

Waste Disposal

Tributyl phosphate is dissolved in a combustible solvent and is burned in a chemical incinerator equipped with an afterburner and scrubber.

Tributyl phosphate Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Tributyl phosphate Suppliers

-Wuxi Donghu Chemical Factory
Tel
0510-88791905 15861586823
Email
andypuchina@hotmail.com
Country
China
ProdList
1
Advantage
58
Zhangjiagang Xinya Chemical Co., Ltd.
Tel
0512-58980899 13915696858
Email
sales@zjgxinyachem.com
Country
China
ProdList
27
Advantage
58
Jinan Hongli Chemical Industry Co. , Ltd.
Tel
18354135979
Email
970731907@qq.com
Country
China
ProdList
69
Advantage
58
Guangdong wengjiang Chemical Reagent Co., Ltd.
Tel
0751-2886750 13927877953
Fax
0751-2886750
Email
3005811397@qq.com
Country
China
ProdList
13487
Advantage
58
Beijing Leaderherb Bio-Tech. Co., LTD.
Tel
010-51288246
Email
300abc@sina.com
Country
China
ProdList
59
Advantage
58
Biopole Pharmatech Co., Ltd.
Tel
0512-65974739-0 15151475053
Email
mengqi_biopole@163.com
Country
China
ProdList
37
Advantage
58
Qingdao Ruifengyuan Chemical Co., Ltd.
Tel
13375559818 13375559818
Email
cfy69@163.com
Country
China
ProdList
221
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
More
Less

View Lastest Price from Tributyl phosphate manufacturers

Jinan Finer Chemical Co., Ltd
Product
Tributyl phosphate 126-73-8
Price
US $2.00/kg
Min. Order
1kg
Purity
≥99%
Supply Ability
2000mt/year
Release date
2023-03-23
Speranza Chemical Co., Ltd.
Product
Tributyl phosphate,99% 126-73-8
Price
US $20.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200tons/ year
Release date
2020-03-11
Hebei Dangtong Import and export Co LTD
Product
Tributyl phosphate 126-73-8
Price
US $4860.00-4400.00/Tons
Min. Order
1Tons
Purity
99.99%
Supply Ability
200Tons
Release date
2023-04-12

126-73-8, Tributyl phosphateRelated Search:


  • AURORA KA-1641
  • BUTYL PHOSPHATE
  • O,O,O-Tributylphosphate
  • TRIBUTYLPHOSPHATE extrapure
  • Nitrogen-Oxygen free radical piperidycol
  • Phosphoric acid tributyl
  • Tributyl phosphate 5g [126-73-8]
  • Tributyl phosphate 10g [126-73-8]
  • Tributyl phosphate, 99+% 1LT
  • Tributyl phosphate puriss., >=99.0% (GC)
  • Tributylphosph
  • Tributyl phosphate, 99%, analytical grade
  • Tributyl phosphate, Tri-n-butyl phosphate, Butyl phosphate,Phosphoric acid tri-n-butyl ester
  • ANTIFOAM T
  • Butyl phosphate, ((BuO)3PO)
  • Butyl phosphate, tri-
  • Celluphos 4
  • celluphos4
  • Disflamoll TB
  • disflamolltb
  • Kronitex TBP
  • mcs2495
  • Phos-Ad 100
  • phosphatedetributyle
  • Syn-O-Ad 8412
  • Tributilfosfato
  • Tributoxyphosphine oxide
  • tributoxyphosphineoxide
  • tributyl
  • Tributyl ester of phosphoric acid
  • Tributyle
  • Tributyle(phosphate de)
  • tributyle(phosphatede)
  • tributyle(phosphatede)(french)
  • Tributylfosfaat
  • Tributylfosfat
  • Tributylphosphat
  • tri-butylphosphat
  • tributylphosphate(tbp)
  • Tributylphsophate
  • TBP
  • N-BUTYL-O-PHOSPHORIC ACID
  • N-BUTYL PHOSPHATE
  • N-TRIBUTYL PHOSPHATE
  • PHOSPHORIC ACID TRIBUTYL ESTER
  • PHOSPHORIC ACID TRI-N-BUTYL ESTER
  • TRIBUTYL PHOSPHATE
  • TRI-N-BUTYL ORTHOPHOSPHATE
  • TRI-N-BUTYL PHOSPHATE
  • tributylphospate
  • Phosphorsuretri-n-butylester
  • TRIBUTYL PHOSPHATE, 98+%
  • Tributyl Phosphsate
  • TRIBUTYL PHOSPHATE, FOR EXTRACTION ANALY SIS
  • TRIBUTYL PHOSPHATE, 99+%
  • TRIBUTYL PHOSPHATE GC STANDARD
  • TributylPhosphate,Certified
  • linsuansandinhzi