Azido-PEG7-acid
- Product Name
- Azido-PEG7-acid
- CAS No.
- 361189-66-4
- Chemical Name
- Azido-PEG7-acid
- Synonyms
- N3-PEG6-COOH;Azido-PEG7-acid;Azido-PEG6-Acid;N3-PEG7-CH2CH2COOH;Azido-PEG6-CH2CH2COOH;Azido-PEG6-propionic acid;Azido-PEG6-acid,N3-PEG6-acid;1-azido-3,6,9,12,15,18-hexaoxahenicosan-21-oic acid;3-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid;N3-PEG6-CH2CH2COOH/Propanoic acid, 3-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]-
- CBNumber
- CB13062206
- Molecular Formula
- C15H29N3O8
- Formula Weight
- 379.41
- MOL File
- 361189-66-4.mol
Azido-PEG7-acid Property
- storage temp.
- Storage temp. 2-8°C
- solubility
- Soluble in Water, DMSO, DCM, DMF
- form
- Liquid
- color
- Colorless to light yellow
- InChI
- InChI=1S/C15H29N3O8/c16-18-17-2-4-22-6-8-24-10-12-26-14-13-25-11-9-23-7-5-21-3-1-15(19)20/h1-14H2,(H,19,20)
- InChIKey
- KQYQHDQBMAJDRL-UHFFFAOYSA-N
- SMILES
- C(OCCOCCC(=O)O)COCCOCCOCCOCCN=[N+]=[N-]
Safety
- HS Code
- 2942000090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- BP-25636
- Product name
- Azido-PEG7-acid
- Purity
- 98%
- Packaging
- 100mg
- Price
- $230
- Updated
- 2021/12/16
- Product number
- BP-20612
- Product name
- Azido-PEG6-acid
- Purity
- 98%
- Packaging
- 100mg
- Price
- $240
- Updated
- 2021/12/16
- Product number
- BP-25636
- Product name
- Azido-PEG7-acid
- Purity
- 98%
- Packaging
- 250mg
- Price
- $360
- Updated
- 2021/12/16
- Product number
- POL0002369
- Product name
- AZIDO-PEG6-ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495.19
- Updated
- 2021/12/16
- Product number
- BP-25636
- Product name
- Azido-PEG7-acid
- Purity
- 98%
- Packaging
- 500mg
- Price
- $540
- Updated
- 2021/12/16
Azido-PEG7-acid Chemical Properties,Usage,Production
Description
Azido-PEG6-acid is a aqueous soluble PEG linker containing an azide and a terminal carboxylic acid. The azide (N3) group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Uses
Azido-PEG6-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG6-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azido-PEG7-acid Preparation Products And Raw materials
Raw materials
Preparation Products
Azido-PEG7-acid Suppliers
- Tel
- 13892832556
- 2440688701@qq.com
- Country
- China
- ProdList
- 1994
- Advantage
- 58
- Tel
- 0913-7167565 13852786668
- 605375102@qq.com
- Country
- China
- ProdList
- 212
- Advantage
- 58
- Tel
- 18754046789
- yiming@163.cn
- Country
- China
- ProdList
- 65
- Advantage
- 58
- Tel
- 021-61551611 13296011611
- Fax
- +86 21-50676805
- contact@trustwe.com
- Country
- China
- ProdList
- 9895
- Advantage
- 58
- Tel
- 0431-0431-80514535 19917294565
- et@chemextension.com
- Country
- China
- ProdList
- 3936
- Advantage
- 55
- Tel
- 027-65563561
- Fax
- 86-27-59218822
- sales@borenpharm.com
- Country
- China
- ProdList
- 1245
- Advantage
- 55
- Tel
- 021-68882955 17721395025
- Fax
- 021-68882955
- 2423903095@qq.com
- Country
- China
- ProdList
- 4991
- Advantage
- 58
- Tel
- 0512-56316828
- Fax
- 0512-56316826
- info@amateksci.com
- Country
- China
- ProdList
- 28785
- Advantage
- 58
- Tel
- 571-86101219 18768477782
- Fax
- -
- sales09@leobiochem.com
- Country
- China
- ProdList
- 433
- Advantage
- 58
- Tel
- 021-61469567 13482353728
- Fax
- 021-61161605
- sales@fdc-chemical.com
- Country
- China
- ProdList
- 9717
- Advantage
- 58
View Lastest Price from Azido-PEG7-acid manufacturers
- Product
- 1-azido-3,6,9,12,15,18-hexaoxahenicosan-21-oic acid 361189-66-4
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2025-09-12
- Product
- azido-PEG6-Acid 361189-66-4
- Price
- US $0.00/g
- Min. Order
- 5g
- Purity
- >98.00%
- Supply Ability
- 5g
- Release date
- 2024-03-23