9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID, 1,15-LACTONE
- Product Name
- 9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID, 1,15-LACTONE
- CAS No.
- 55314-49-3
- Chemical Name
- 9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID, 1,15-LACTONE
- Synonyms
- u47473;13e,15s)-1-alph;pgf2-alpha1,15-lactone;Prostaglandin F2α 1,15-lactone;PROSTAGLANDIN F2ALPHA 1,15-LACTONE;prosta-5,13-dien-1-oicacid,9,11,15-trihydroxy-,lambda-lactone,(5z,9-alpha,1;9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID, 1,15-LACTONE;(1R,3Z,10S,11E,13R,14R,16S)-14,16-dihydroxy-10-pentyl-9-oxabicyclo[11.3.0]hexadeca-3,11-dien-8-one
- CBNumber
- CB2305970
- Molecular Formula
- C20H32O4
- Formula Weight
- 336.47
- MOL File
- 55314-49-3.mol
9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID, 1,15-LACTONE Property
- storage temp.
- Store at -20°C
- solubility
- DMF: >20.4 mg/ml; DMSO: >10 mg/ml; Ethanol: >105 mg/ml; Ethanol:PBS (30:70): 8 mg/ml; PBS (pH 7.2): <50 ug/ml
- form
- A crystalline solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H360May damage fertility or the unborn child
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P308+P313IF exposed or concerned: Get medical advice/attention.
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 16120
- Product name
- Prostaglandin F2α 1,15-lactone
- Purity
- ≥99%
- Packaging
- 1mg
- Price
- $87
- Updated
- 2024/03/01
- Product number
- 16120
- Product name
- Prostaglandin F2α 1,15-lactone
- Purity
- ≥99%
- Packaging
- 5mg
- Price
- $384
- Updated
- 2024/03/01
- Product number
- 16120
- Product name
- Prostaglandin F2α 1,15-lactone
- Purity
- ≥99%
- Packaging
- 10mg
- Price
- $680
- Updated
- 2024/03/01
- Product number
- 1548AH
- Product name
- 9alpha,11alpha,15S-Trihydroxy-prosta-5Z,13E-dien-1-oicacid,1,15-lactone
- Packaging
- 1mg
- Price
- $194
- Updated
- 2021/12/16
9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID, 1,15-LACTONE Chemical Properties,Usage,Production
Description
PGF2α 1,15-
Uses
PGF2α 1,15-lactone (Prostaglandin F2α 1,15-lactone) is a lipid-soluble internal ester of PGF2α. PGF2α 1,15-lactone decreases menstrual cycle lengths in non-pregnant rhesus monkeys. PGF2α 1,15-lactone terminates early pregnancy in the monkey[1].
in vivo
PGF2α 1,15-lactone (5 mg for i.v.; 3 mg for intramuscularly) terminates early pregnancy in the monkey[1].
| Animal Model: | Rhesus monkey (trimester pregnant)[1] |
| Dosage: | 5 mg for i.v.; 3 mg for intramuscularly |
| Administration: | IV on days 30 and 31, 31 and 32, or 33 and 34; Intramuscularly on days 29 and 30, 30 and 31, or 33 and 34 |
| Result: | Aborted between 36 and 48 hr after treatment, Within 10 minutes after treatment there was a significant increase in uterine tone and frequency of contractions. |
References
[1] Spilman CH, et al. Effects of PGF2alpha and PGF2alpha, 1-15 lactone on the corpus luteum and on early pregnancy in the rhesus monkey. Prostaglandins. 1977 Sep;14(3):477-88. DOI:10.1016/0090-6980(77)90262-3
9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID, 1,15-LACTONE Preparation Products And Raw materials
Raw materials
Preparation Products
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