ChemicalBook > CAS DataBase List > Amino-PEG4-t-Boc-Hydrazide
Amino-PEG4-t-Boc-Hydrazide
- Product Name
- Amino-PEG4-t-Boc-Hydrazide
- CAS No.
- 1263047-17-1
- Chemical Name
- Amino-PEG4-t-Boc-Hydrazide
- Synonyms
- NH2-PEG4-HZ-Boc;Amino-PEG4-hydrazide-Boc;H2N-PEG4-CH2CH2CONHNHBoc;Amino-PEG4- Boc-Hydrazide;Amino-PEG4-t-Boc-Hydrazide;Amino-PEG4-N-Boc-hydrazide;Amino-dPEG??-t-boc-hydrazide (QBD-10041);2-BOC-Hydrozino 3-amino(peg4)propionamide;tert-Butyl 18-amino-4-oxo-7,10,13,16-tetraoxa-2,3-diazaoctadecan-1-oate;7,10,13,16-Tetraoxa-2,3-diazaoctadecanoic acid, 18-amino-4-oxo-, 1,1-dimethylethyl ester
- CBNumber
- CB23062319
- Molecular Formula
- C16H33N3O7
- Formula Weight
- 379.45
- MOL File
- 1263047-17-1.mol
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Amino-PEG4-t-Boc-Hydrazide Property
- Density
- 1.115±0.06 g/cm3(Predicted)
- pka
- 8.99±0.43(Predicted)
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N-Bromosuccinimide Price
TRC
- Product number
- H289600
- Product name
- H2N-DPEG(4)-NHNH-Boc
- Packaging
- 100mg
- Price
- $350
- Updated
- 2021/12/16
Iris Biotech GmbH
- Product number
- PEG1335
- Product name
- H2N-dPEG(4)-NHNH-Boc
- Packaging
- 100mg
- Price
- $351
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- POL0002284
- Product name
- H2N-DPEG-(4)-NHNH-BOC
- Purity
- 95.00%
- Packaging
- 100MG
- Price
- $472.5
- Updated
- 2021/12/16
Apolloscientific
- Product number
- BIPG1069
- Product name
- Amino-PEG4-t-Boc-Hydrazide
- Packaging
- 100mg
- Price
- $546
- Updated
- 2021/12/16
Iris Biotech GmbH
- Product number
- PEG1335
- Product name
- H2N-dPEG(4)-NHNH-Boc
- Packaging
- 1g
- Price
- $1296
- Updated
- 2021/12/16
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Amino-PEG4-t-Boc-Hydrazide Chemical Properties,Usage,Production
Description
Amino-PEG4-t-Boc-hydrazide is a PEG linker containing an amino group and a Boc-protected hydrazide. The hydrophilic PEG spacer increases solubility in aqueous media. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc can be deprotected under mild acidic conditions to form a reactive hydrazide, which can then be coupled with various carbonyl groups.
Uses
Amino-PEG4-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Amino-PEG4-t-Boc-Hydrazide Preparation Products And Raw materials
Raw materials
Preparation Products
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Amino-PEG4-t-Boc-Hydrazide Suppliers
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
- Tel
- tp@aladdinsci.com
- Country
- United States
- ProdList
- 52923
- Advantage
- 58
- Tel
- --
- Fax
- --
- sales@combi-blocks.com
- Country
- United States
- ProdList
- 6618
- Advantage
- 69